Who owns the IP
The organizations most actively patenting around this compound, ranked by referenced patent volume.
| # | Assignee | Patents |
|---|---|---|
| 1 | Genentech Inc | 3,458 |
| 2 | F Hoffmann La Roche AG | 1,521 |
| 3 | The University of Texas System | 738 |
| 4 | Institut National de la Santé et de la Recherche Médicale | 414 |
| 5 | The University of Texas at Austin | 339 |
| 6 | Gilead Sciences Inc | 303 |
| 7 | Merck Sharp & Dohme LLC | 253 |
| 8 | MedImmune Ltd | 239 |
| 9 | Toray Industries Inc | 222 |
| 10 | Mereo Biopharma 5 Inc | 202 |
Explore the full landscape
This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.
Visit CyprisWhere innovation is concentrated
Patent classifications ranked by volume reveal the technical domains with the most active filing.
| # | Code | Area | Patents |
|---|---|---|---|
| 1 | A61P | Therapeutic activity (drug indications) | 19,627 |
| 2 | A61K | Medicinal preparations | 19,242 |
| 3 | C07K | Peptides | 12,994 |
| 4 | C07D | Heterocyclic compounds | 5,127 |
| 5 | C12N | Microorganisms, enzymes | 4,374 |
| 6 | G01N | Investigating / analysing materials | 3,823 |
| 7 | C12Q | Measuring/testing involving enzymes | 1,866 |
| 8 | Y02A | Climate change adaptation | 1,864 |
| 9 | C12Y | Enzyme nomenclature (EC numbers) | 786 |
| 10 | C07F | Organometallic compounds | 657 |
AI mapped opportunity space
This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.
See Cypris in actionMost-cited patents
Patents ranked by forward citations reveal the foundational inventions the field continues to build on.
| Title | Year | Assignee | Cited by |
|---|---|---|---|
| Application of 6-diazo-5-oxo-L-norleucine in preparation of medicine for preventing and treating psoriasis | 2021 | SHENZHEN FUTIAN HOSPITAL FOR RHEUMATIC DISEASES | 3 |
| METHODS FOR BIOANALYSIS OF 6-DIAZO-5-OXO-L-NORLEUCINE (DON) AND OTHER GLUTAMINE ANTAGONISTS | 2016 | Johns Hopkins University | 2 |
| PRODRUGS OF 6-DIAZO-5-OXO-L-NORLEUCINE | 2022 | Institute of Organic Chemistry and Biochemistry | 1 |
| NQO1 activated 6-diazo-5-oxo-L-norleucine prodrug and preparation method and application thereof | 2021 | CHINA PHARMACEUTICAL UNIVERSITY | 1 |
| PHARMACEUTICAL COMPOSITION CONTAINING 6-DIAZO-5-OXO-L-NORLEUCINE FOR TREATMENT OF INFLAMMATORY SKIN DISEASE | 2020 | KIM, MIN JUNG | 1 |
Where research is gaining momentum
Research themes ranked by publication activity show where scientific interest is accelerating around this compound.
| # | Research topic | Papers |
|---|---|---|
| 1 | Biochemical and Molecular Research | 2 |
| 2 | Amino Acid Enzymes and Metabolism | 1 |
| 3 | Cancer therapeutics and mechanisms | 1 |
| 4 | Cancer, Hypoxia, and Metabolism | 1 |
| 5 | Clinical Nutrition and Gastroenterology | 1 |
| 6 | Colorectal Cancer Treatments and Studies | 1 |
| 7 | Corneal Surgery and Treatments | 1 |
| 8 | Enzyme function and inhibition | 1 |
| 9 | Nitric Oxide and Endothelin Effects | 1 |
| 10 | Pancreatic function and diabetes | 1 |
Technology trend analysis
Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.
See Cypris in actionWho's driving the science
The most-published authors working with this compound, alongside their primary affiliations.
| # | Author | Affiliation | Papers |
|---|---|---|---|
| 1 | Barbara S. Slusher | Johns Hopkins University | 17 |
| 2 | David A. Cooney | National Cancer Institute | 6 |
| 3 | D. M. Kochhar | University of Virginia | 5 |
| 4 | Eva Prchalová | Johns Hopkins University | 5 |
| 5 | H Zalkin | Purdue University West Lafayette | 5 |
| 6 | Jesse Alt | Johns Hopkins University | 5 |
| 7 | Bengt Långström | Uppsala University Hospital | 4 |
| 8 | Camilo Rojas | Johns Hopkins University | 4 |
| 9 | Joseph Roberts | University of South Carolina | 4 |
| 10 | Ajit G. Thomas | Johns Hopkins University | 3 |
Research leaders
This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.
See Cypris in actionThe literature that defines it
The most-cited papers anchoring the scientific record for this compound.
| Title | Year | Cited by | Topic |
|---|---|---|---|
| Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation | 2013 | 602 | Protein Kinase Regulation and GTPase Signaling |
| Functional significance of cumulus expansion in the mouse: Roles for the preovulatory synthesis of hyaluronic acid within the cumulus mass | 1993 | 291 | Sperm and Testicular Function |
| Glutamine and Cancer | 1993 | 289 | Cancer, Hypoxia, and Metabolism |
| Lumen formation by epithelial cell lines in response to collagen overlay: a morphogenetic model in culture. | 1982 | 281 | Cancer Cells and Metastasis |
| We're Not “DON” Yet: Optimal Dosing and Prodrug Delivery of<i>6-Diazo-5-oxo-L-norleucine</i> | 2018 | 251 | Cancer-related Molecular Pathways |
Frequently asked questions
Common questions about this compound's patent and research landscape, answered from the underlying data.
What is the molecular formula and weight of 6-diazo-5-oxo-L-norleucine?
Which organizations hold the most patents related to this compound?
What research topics are most prominently associated with 6-diazo-5-oxo-L-norleucine?
Who are the most prolific authors publishing on this compound?
What are the primary patent classification areas for research on this compound?