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Guanidine thiocyanate

(diaminomethylideneamino) thiocyanate · also: guanidine monothiocyanate

FormulaC2H4N4S
Mol. weight116.142
PubChem CID547739
InChIKeyFZPKSSRLAIBRQA-UHFFFAOYSA-N
SMILESC(#N)SN=C(N)N
11,316Patents
237Research papers236 indexed in detail
831Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1BASF SE466
2Roche Holding AG324
3Abbott Laboratories215
4Kirin Holdings Co Ltd183
5Dana Farber Cancer Institute Inc150
6Takeda Pharmaceutical Co Ltd145
7Qiagen NV141
8Fujifilm Holdings Corp123
9Johnson and Johnson122
10Bristol Myers Squibb Co121

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C12NMicroorganisms, enzymes4,986
2C07KPeptides3,958
3C12QMeasuring/testing involving enzymes3,856
4A61KMedicinal preparations3,100
5G01NInvestigating / analysing materials2,303
6A61PTherapeutic activity (drug indications)2,289
7B01L696
8Y02AClimate change adaptation570
9C12YEnzyme nomenclature (EC numbers)529
10C12PFermentation, enzyme processes500

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Extraction of DNA by boiling cells in an alkaline phenol/guanidine thiocyanate solution1999Mayo Clinic Inc41
Hybridization buffer containing guanidine thiocyanate2018Abbott Laboratories6
Preparation method of guanidine thiocyanate20211
Quick drying device for guanidine thiocyanate20250
Dewatering device is used in guanidine thiocyanate preparation20220

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Alasdair J. EdgarKing's College London4
2Brigitte Berger‐BächiUniversity of Zurich4
3Susan L. UprichardUniversity of Illinois Chicago3
4Franca BianchiUniversity of Bologna2
5Supaporn WacharapluesadeeChulalongkorn University2
6Lucia LimidoFondazione IRCCS Istituto Neurologico Carlo Besta2
7Fabrizio TagliaviniFondazione IRCCS Istituto Neurologico Carlo Besta2
8Vincenzo LionettiScuola Superiore Sant'Anna2
9Charles BevinsUniversity of California, Davis2
10Alfredo FuscoUniversity of Naples Federico II2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of guanidine thiocyanate?

Guanidine thiocyanate has the molecular formula C2H4N4S and a molecular weight of 116.142 g/mol. It is also known by the canonical name (diaminomethylideneamino) thiocyanate.

Which organizations hold the most patents related to guanidine thiocyanate?

The leading patent assignees for guanidine thiocyanate are BASF SE with 466 patents, Roche Holding AG with 324 patents, Abbott Laboratories with 215 patents, Kirin Holdings Co Ltd with 183 patents, and Dana Farber Cancer Institute Inc with 150 patents.

What are the primary technical applications of guanidine thiocyanate based on patent classification?

The largest patent classifications for guanidine thiocyanate applications are C12N (Biochemistry and Biotechnology) with 4986 patents, C07K (Organic Chemistry - amino acids and peptides) with 3958 patents, and C12Q (Biochemical measuring and analyzing) with 3856 patents. These reflect its use in molecular biology, nucleic acid extraction, and diagnostic applications.

What is a notable scientific publication about guanidine thiocyanate?

A highly cited publication is 'The single-step method of RNA isolation by acid guanidinium thiocyanate–phenol–chloroform extraction: twenty-something years on' from 2006, which has received 2110 citations and covers molecular biology techniques and applications.

How has patent activity for guanidine thiocyanate changed in recent years?

Patent activity has shown fluctuation, with 356 patents filed in 2016, increasing to a peak of 438 patents in 2023, then declining to 399 in 2024 and 272 in 2025. Over the last three years (2023-2025), a total of 831 patents were filed.

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