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Homovanillyl alcohol

4-(2-hydroxyethyl)-2-methoxyphenol · also: Guaiacyl ethanol · Vanillylmethanol · Homovanillin alcohol · Homovanilline alcohol · 2-(4-Guaiacyl)-ethanol · 4-(2-Hydroxyethyl)guaiacol

FormulaC9H12O3
Mol. weight168.192
PubChem CID16928
InChIKeyXHUBSJRBOQIZNI-UHFFFAOYSA-N
SMILESCOC1=C(C=CC(=C1)CCO)O
672Patents
81Research papers80 indexed in detail
83Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Nestle SA54
2Qiagen NV22
3DSM Firmenich AG21
4Henkel AG and Co KGaA18
5Mitsubishi Gas Chemical Co Inc18
6Rutgers, The State University of New Jersey13
7Agilent Technologies Inc12
8AstraZeneca PLC12
9Advanz Pharma Corp Ltd11
10Pfizer Inc11

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)255
2A61KMedicinal preparations211
3C07CAcyclic and carbocyclic compounds154
4C08GPolymers from non-vinyl bonds (e.g. polyamides, polyesters)102
5A23LFoods and beverages (general)100
6C07DHeterocyclic compounds89
7C08LPolymer compositions (blends)62
8A23VFoods, foodstuffs - indexing scheme51
9C07BGeneral methods of organic chemistry48
10C09DCoatings, paints, varnishes45

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
HOMOVANILLYL ALCOHOL (HVA), HVA ISOMER, METHODS OF MAKING COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND METHODS USING SUCH COMPOUNDS2019Nestle SA21
Homovanillyl alcohol (HVA), HVA isomers, methods of making compositions comprising such compounds, and methods of using such compounds2024Nestle SA0
Method for catalyzing industrial lignin to convert 2, 6-di-tert-butyl-p-cresol and homovanillyl alcohol by molybdenum-loaded carbon nitride20230
HOMOVANILLYL ALCOHOL (HVA), HVA ISOMER, METHODS OF MAKING COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND METHODS USING SUCH COMPOUNDS2023Nestle SA0
HOMOVANILLYL ALCOHOL (HVA), HVA ISOMER, METHODS OF MAKING COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND METHODS USING SUCH COMPOUNDS2020Nestle SA0

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20171
20211
20233

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Giulia CoronaUniversity of Reading4
2Donatella CarusoUniversity of Milan4
3David J. EdwardsUniversity of Pittsburgh4
4Monica DeianaUniversity of Cagliari3
5Alessandra IncaniUniversity of Cagliari3
6David VauzourUniversity of Reading3
7Kurt RackéJohannes Gutenberg University Mainz3
8Ma DessìUniversity of Cagliari3
9Rossana FagnaniUniversity of Milan2
10Angela AtzeriUniversity of Cagliari2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of homovanillyl alcohol?

Homovanillyl alcohol has the molecular formula C9H12O3 with a molecular weight of 168.192. Its canonical IUPAC name is 4-(2-hydroxyethyl)-2-methoxyphenol, and it is also known by numerous synonyms including guaiacyl ethanol, vanillylmethanol, and 4-hydroxy-3-methoxyphenethanol.

Which organizations hold the most patents related to homovanillyl alcohol?

Nestle SA is the leading patent assignee with 54 patents, followed by Qiagen NV with 22 patents and DSM Firmenich AG with 21 patents. Other significant patent holders include Henkel AG and Co KGaA and Mitsubishi Gas Chemical Co Inc, each with 18 patents.

What has been the recent patenting trend for homovanillyl alcohol?

Patent activity has shown a general upward trend, with 48 patents filed in 2023 and 40 in 2022, representing significant increases from earlier years. The last three years (2023-2025) account for 110 patents out of 672 total, with 83 patents filed in the last 3-year period noted in the coverage data.

What are the primary technical areas where homovanillyl alcohol is applied?

The most prevalent CPC subclass is A61P (specific therapeutic activity of chemical compounds), with 255 patents, followed by A61K (preparations for medical, dental, or toilet purposes) with 211 patents. Other significant areas include C07C (acyclic or carbocyclic compounds) with 154 patents and A23L (food; food preparation) with 100 patents, indicating applications spanning pharmaceuticals, chemistry, and food.

What key patents has Nestle SA filed regarding homovanillyl alcohol?

Nestle SA filed multiple patents on homovanillyl alcohol and related compounds, including WO-2019092069-A2 (filed in 2019 with 21 citations), CN-111343993-B (2024), EP-3706759-B1 (2023), and EP-3706759-A2 (2020). These patents cover homovanillyl alcohol isomers, methods of making compositions comprising such compounds, and methods of using such compounds.

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