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Homovanillyl alcohol

4-(2-hydroxyethyl)-2-methoxyphenol · also: Guaiacyl ethanol, Vanillylmethanol, Homovanillin alcohol, Homovanilline alcohol, 2-(4-Guaiacyl)-ethanol, 4-(2-Hydroxyethyl)guaiacol

FormulaC9H12O3
Mol. weight168.192
PubChem CID16928
InChIKeyXHUBSJRBOQIZNI-UHFFFAOYSA-N
SMILESCOC1=C(C=CC(=C1)CCO)O
672Patents
81Research papers
89Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Societe des Produits Nestle SA54
2Nestle SA30
3Qiagen Genomics Inc22
4Mitsubishi Gas Chemical Co Inc18
5Rutgers, The State University of New Jersey13
6Agilent Technologies Inc12
7AstraZeneca AB12
8Henkel AG and Co KGaA11
9Xerox Corp10
10Indena SpA9

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)255
2A61KMedicinal preparations211
3C07CAcyclic and carbocyclic compounds154
4C08GPolymers from non-vinyl bonds (e.g. polyamides, polyesters)102
5A23LFoods and beverages (general)100
6C07DHeterocyclic compounds89
7C08LPolymer compositions (blends)62
8A23VFoods, foodstuffs - indexing scheme51
9C07BGeneral methods of organic chemistry48
10C09DCoatings, paints, varnishes45

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
HOMOVANILLYL ALCOHOL (HVA), HVA ISOMER, METHODS OF MAKING COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND METHODS USING SUCH COMPOUNDS2019Nestec SA21
Homovanillyl alcohol (HVA), HVA isomers, methods of making compositions comprising such compounds, and methods of using such compounds2024Societe des Produits Nestle SA0
Method for catalyzing industrial lignin to convert 2, 6-di-tert-butyl-p-cresol and homovanillyl alcohol by molybdenum-loaded carbon nitride2023Huaiyin Normal University0
HOMOVANILLYL ALCOHOL (HVA), HVA ISOMER, METHODS OF MAKING COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND METHODS USING SUCH COMPOUNDS2023Societe des Produits Nestle SA0
HOMOVANILLYL ALCOHOL (HVA), HVA ISOMER, METHODS OF MAKING COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND METHODS USING SUCH COMPOUNDS2020Societe des Produits Nestle SA0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Cholinesterase and Neurodegenerative Diseases1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1David J. EdwardsUniversity of Pittsburgh4
2Donatella CarusoUniversity of Milan4
3Giulia CoronaUniversity of Reading4
4Alessandra IncaniUniversity of Cagliari3
5David VauzourUniversity of Reading3
6Kurt RackéJohannes Gutenberg University Mainz3
7Ma DessìUniversity of Cagliari3
8Monica DeianaUniversity of Cagliari3
9Aalt BastMaastricht University2
10Alexander L. BeckmanAlfred I. duPont Hospital for Children2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of homovanillyl alcohol?

Homovanillyl alcohol has the molecular formula C9H12O3 and a molecular weight of 168.192. It is also known by its IUPAC name 4-(2-hydroxyethyl)-2-methoxyphenol.

Which organizations hold the most patents involving homovanillyl alcohol?

Societe des Produits Nestle SA holds the most patents involving homovanillyl alcohol with 54 patents, followed by Nestle SA with 30 patents. Other significant patent holders include Qiagen Genomics Inc with 22 patents and Mitsubishi Gas Chemical Co Inc with 18 patents.

What are the primary patent classification areas for homovanillyl alcohol?

The primary CPC subclasses for homovanillyl alcohol patents are Pharmaceutical Preparations (A61P) with 255 patents, Medicinal Preparations (A61K) with 211 patents, and Organic Chemistry compounds (C07C) with 154 patents. Other significant areas include macromolecular chemistry (C08G) with 102 patents and food preparations (A23L) with 100 patents.

What were the recent patent filing trends for homovanillyl alcohol?

Patent activity involving homovanillyl alcohol has been increasing in recent years. In 2023, there were 48 patents filed, followed by 32 in 2024. Over the last 3 years (2023-2025), a total of 89 patents have been filed involving this compound.

What key patents have been issued for homovanillyl alcohol and its compositions?

Notable patents include WO-2019092069-A2 titled 'HOMOVANILLYL ALCOHOL (HVA), HVA ISOMER, METHODS OF MAKING COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND METHODS USING SUCH COMPOUNDS' issued in 2019, and CN-111343993-B issued in 2024, both assigned to Societe des Produits Nestle SA. EP-3706759-B1, also assigned to Societe des Produits Nestle SA, was issued in 2023.

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