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Girard-T reagent

(2-hydrazinyl-2-oxoethyl)-trimethylazanium chloride · also: girard-t, Girard T reagent, Girard reagent T, Giralt's reagent T, Girard's reagent T, Ammonium, chloride, hydrazide

FormulaC5H14ClN3O
Mol. weight167.637
PubChem CID67156
InChIKeyYSULOORXQBDPCU-UHFFFAOYSA-N
SMILESC[N+](C)(C)CC(=O)NN.[Cl-]
1,252Patents
42Research papers
85Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Procter and Gamble Co62
2Meiji Seika Kaisha Ltd28
3Notable Labs Ltd28
4Sanofi Aventis France27
5Bristol Myers Co24
6BASF SE23
7Shionogi and Co Ltd23
8Astellas Pharma Inc19
9Fujisawa Pharmaceutical Co Ltd19
10Sigma-Aldrich Co LLC16

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C07DHeterocyclic compounds438
2A61PTherapeutic activity (drug indications)292
3C07CAcyclic and carbocyclic compounds182
4A61KMedicinal preparations179
5G01NInvestigating / analysing materials144
6Y02PClimate change mitigation: production138
7C07J127
8C07FOrganometallic compounds87
9D21H77
10C08FPolymers from C=C unsaturated bonds74

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Use of girard t reagent in quantitative aliphatic n-aldehyde determinations1965GADDIS ADAM M1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Chengjian WangNorthwest University3
2Linjuan HuangNorthwest University3
3Mohsen M. MostafaMansoura University3
4Peter J. CrickSwansea University3
5William J. GriffithsSwansea University3
6Yuqin WangSwansea University3
7Zhongfu WangNorthwest University3
8Argyro G. FragkakiNational Centre of Scientific Research "Demokritos"2
9Bryn FlindersMaastricht University2
10David W. JohnsonWomen's and Children's Hospital2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition and molecular formula of Girard-T reagent?

Girard-T reagent has the molecular formula C5H14ClN3O with a molecular weight of 167.637. Its canonical name is (2-hydrazinyl-2-oxoethyl)-trimethylazanium chloride, reflecting its structure as a trimethylammonium salt with a hydrazide functional group.

Which organizations hold the most patents involving Girard-T reagent?

The top patent holders are Procter and Gamble Co with 62 patents, followed by Meiji Seika Kaisha Ltd and Notable Labs Ltd each with 28 patents, and Sanofi Aventis France with 27 patents.

What analytical applications are documented for Girard-T reagent in recent research?

Girard-T reagent has been applied in mass spectrometry-based analytical methods, including derivatization for LC−MS/MS detection of DNA repair markers, MALDI-TOF-MS imaging analysis of steroids and glycans, and detection of drug metabolites in biological tissues. Applications span DNA repair mechanisms, mass spectrometry techniques, glycosylation research, and pharmacogenetics.

How has patent activity involving Girard-T reagent trended in recent years?

Patent activity has shown growth in recent years, with 85 patents filed in the last 3 years. Notable activity occurred in 2022 with 42 patents and 2024 with 38 patents, indicating sustained research and development interest in applications of this compound.

What patent technology classes are most associated with Girard-T reagent patents?

The most prevalent patent classifications are C07D (organic chemistry compounds) with 438 patents, A61P (pharmaceutical applications) with 292 patents, C07C (acyclic compounds) with 182 patents, and A61K (pharmaceutical preparations) with 179 patents, indicating concentration in pharmaceutical chemistry and drug development areas.

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