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girard-t

(2-hydrazinyl-2-oxoethyl)-trimethylazanium chloride · also: girardtreagent, Girard T reagent, Girard reagent T, Girards Reagent T, Betaine hydrazide hydrochloride, Trimethylaminoacetohydrazide chloride

FormulaC5H14ClN3O
Mol. weight167.637
PubChem CID67156
InChIKeyYSULOORXQBDPCU-UHFFFAOYSA-N
SMILESC[N+](C)(C)CC(=O)NN.[Cl-]
1,252Patents
42Research papers
89Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Procter and Gamble Co62
2Meiji Seika Kaisha Ltd28
3Notable Labs Ltd28
4Sanofi Aventis France27
5Bristol Myers Co24
6BASF SE23
7Shionogi and Co Ltd23
8Fujisawa Pharmaceutical Co Ltd19
9Sigma-Aldrich Co LLC16
10Abbott Laboratories15

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C07DHeterocyclic compounds438
2A61PTherapeutic activity (drug indications)292
3C07CAcyclic and carbocyclic compounds182
4A61KMedicinal preparations179
5G01NInvestigating / analysing materials144
6Y02PClimate change mitigation: production138
7C07J127
8C07FOrganometallic compounds87
9D21H77
10C08FPolymers from C=C unsaturated bonds74

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Use of girard t reagent in quantitative aliphatic n-aldehyde determinations1965GADDIS ADAM M1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Chengjian WangNorthwest University3
2Linjuan HuangNorthwest University3
3Mohsen M. MostafaMansoura University3
4Peter J. CrickSwansea University3
5William J. GriffithsSwansea University3
6Yuqin WangSwansea University3
7Zhongfu WangNorthwest University3
8Argyro G. FragkakiNational Centre of Scientific Research "Demokritos"2
9Bryn FlindersMaastricht University2
10David W. JohnsonWomen's and Children's Hospital2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition and molecular weight of Girard T reagent?

Girard T reagent has the canonical name (2-hydrazinyl-2-oxoethyl)-trimethylazanium chloride with the molecular formula C5H14ClN3O and a molecular weight of 167.637 g/mol.

Which companies hold the most patents involving Girard T reagent?

The top patent assignees are Procter and Gamble Co with 62 patents, followed by Meiji Seika Kaisha Ltd and Notable Labs Ltd each with 28 patents, Sanofi Aventis France with 27 patents, and Bristol Myers Co with 24 patents.

What are the primary research applications of Girard T reagent based on recent scientific literature?

Recent papers demonstrate use of Girard T reagent in mass spectrometry-based applications including DNA damage analysis (Detection of 5-Formyl-2'-deoxyuridine in cellular DNA), detection of pharmaceutical compounds in biological tissues (Triamcinolone Acetonide in cartilage), glycomics analysis (on-target derivatization of reducing glycans), and imaging mass spectrometry of steroid hormones (testosterone visualization in mouse testis).

What is the patent activity trend for Girard T reagent over recent years?

Patent activity has increased substantially, with 90 patents filed in the last 3 years. Annual filings show growth from 22 patents in 2016 to a peak of 42 in 2022, with 28 patents filed in 2025 to date.

Which patent classification areas are most associated with Girard T reagent technology?

The most prevalent CPC subclasses are C07D (heterocyclic compounds) with 438 patents, A61P (medical use classification) with 292 patents, C07C (acyclic or carbocyclic compounds) with 182 patents, A61K (pharmaceutical preparations) with 179 patents, and G01N (measuring and testing) with 144 patents.

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