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Girard-T reagent

(2-hydrazinyl-2-oxoethyl)-trimethylazanium chloride · also: girard-t · Girard reagent T · Girard T reagent · Giralt's reagent T · Girard's reagent T · l-(-)-malicaciddiethylester

FormulaC5H14ClN3O
Mol. weight167.637
PubChem CID67156
InChIKeyYSULOORXQBDPCU-UHFFFAOYSA-N
SMILESC[N+](C)(C)CC(=O)NN.[Cl-]
1,252Patents
42Research papers41 indexed in detail
80Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Procter and Gamble Co62
2Sanofi SA42
3Bristol Myers Squibb Co39
4Pfizer Inc31
5Meiji Holdings Co Ltd28
6Notable Labs Ltd28
7GSK PLC25
8BASF SE23
9Shionogi and Co Ltd23
10Roche Holding AG22

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C07DHeterocyclic compounds438
2A61PTherapeutic activity (drug indications)292
3C07CAcyclic and carbocyclic compounds182
4A61KMedicinal preparations179
5G01NInvestigating / analysing materials144
6Y02PClimate change mitigation: production140
7C07J127
8C07FOrganometallic compounds87
9D21H77
10C08FPolymers from C=C unsaturated bonds74

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Use of girard t reagent in quantitative aliphatic n-aldehyde determinations19651

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20162
20174
20182
20194
20201
20212
20221
20233

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Yuqin WangSwansea University3
2William J. GriffithsSwansea University3
3Linjuan HuangNorthwest University3
4Zhongfu WangNorthwest University3
5Mohsen M. MostafaMansoura University3
6Peter J. CrickSwansea University3
7Chengjian WangNorthwest University3
8Shuichi ShimmaThe University of Osaka2
9Yiannis S. AngelisNational Centre of Scientific Research "Demokritos"2
10Shoujiro OgawaTokyo University of Science2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition and molecular weight of Girard-T reagent?

Girard-T reagent has the molecular formula C5H14ClN3O with a molecular weight of 167.637. Its canonical chemical name is (2-hydrazinyl-2-oxoethyl)-trimethylazanium chloride, and it is also known by several alternative names including trimethylaminoacetohydrazide chloride and betaine hydrazide hydrochloride.

Which organizations hold the most patents involving Girard-T reagent?

The leading patent assignees for Girard-T reagent are Procter and Gamble Co with 62 patents, Sanofi SA with 42 patents, and Bristol Myers Squibb Co with 39 patents. Other significant assignees include Pfizer Inc (31 patents), Meiji Holdings Co Ltd (28 patents), and Notable Labs Ltd (28 patents).

What are the main research topics associated with Girard-T reagent in recent academic literature?

Recent papers using Girard-T reagent focus on mass spectrometry techniques and applications, including derivatization strategies for sensitive detection and imaging mass spectrometry. Specific research areas include DNA repair mechanisms, glycosylation and glycoproteins research, and pharmacogenetics and drug metabolism studies.

Who are the most prolific academic authors publishing on Girard-T reagent applications?

The most active authors publishing on Girard-T reagent include Yuqin Wang, William J. Griffiths, and Peter J. Crick from Swansea University, each with 3 publications. Additionally, Linjuan Huang, Zhongfu Wang, and Chengjian Wang from Northwest University, as well as Mohsen M. Mostafa from Mansoura University, have each published 3 papers on the topic.

What patent technology areas dominate intellectual property filings involving Girard-T reagent?

The leading patent classification codes for Girard-T reagent applications are C07D (organic chemistry compounds) with 438 patents, A61P (pharmaceutical preparations) with 292 patents, and C07C (acyclic organic compounds) with 182 patents. Other significant areas include A61K (medicinal preparations) with 179 patents and G01N (measuring and testing) with 144 patents.

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