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GaPSMA

2-[[5-[3-[[6-[[(5S)-5-carboxy-5-[[(1S)-1,3-dicarboxypropyl]carbamoylamino]pentyl]amino]-6-oxohexyl]amino]-3-oxopropyl]-2-oxidophenyl]methyl-[2-[[5-(2-carboxyethyl)-2-oxidophenyl]methyl-(carboxylatomethyl)amino]ethyl]amino]acetate;gallium-68(3+);hydron · also: Ga PSMA, Prostamedix

FormulaC44H59GaN6O17
Mol. weight1013.704
PubChem CID154572876
InChIKeyAEBYHKKMCWUMKX-LNTZDJBBSA-K
SMILES[H+].C1=CC(=C(C=C1CCC(=O)NCCCCCC(=O)NCCCC[C@@H](C(=O)O)NC(=O)N[C@@H](CCC(=O)O)C(=O)O)CN(CCN(CC2=C(C=CC(=C2)CCC(=O)O)[O-])CC(=O)[O-])CC(=O)[O-])[O-].[68Ga+3]
240Patents
1,122Research papers
167Patents - last 3 years
217Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Progenics Pharmaceuticals Inc19
2Cornell University16
3Deutsches Krebsforschungszentrum DKFZ10
4Novartis AG9
5Johns Hopkins University8
6Albert Ludwigs Universitaet Freiburg7
7University of California San Diego UCSD7
8Curium US LLC6
9Amgen Inc5
10The University of Texas System4

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations194
2A61PTherapeutic activity (drug indications)138
3C07DHeterocyclic compounds66
4C07BGeneral methods of organic chemistry61
5C07KPeptides44
6G06T40
7A61B33
8C07FOrganometallic compounds31
9G16HDigital health, healthcare informatics29
10C07CAcyclic and carbocyclic compounds26

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Prostate Cancer Treatment and Research7
2Glioma Diagnosis and Treatment1
3Renal cell carcinoma treatment1
4Sarcoidosis and Beryllium Toxicity Research1
5Thyroid Cancer Diagnosis and Treatment1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Matthias EiberTechnical University of Munich41
2Ali Afshar‐OromiehUniversity Hospital Heidelberg29
3Jérémie CalaisUniversity of California, Los Angeles26
4Wolfgang P. FendlerEssen University Hospital23
5Benedikt KranzbühlerUniversity of Zurich10
6Boris HadaschikEssen University Hospital19
7Louise EmmettSt Vincent's Hospital Sydney18
8Francesco CeciUniversity of Bologna16
9Uwe HaberkornHeidelberg University15
10Andrea FarolfiUniversity of Bologna14

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of GaPSMA?

GaPSMA has the molecular formula C44H59GaN6O17 with a molecular weight of 1013.704. The compound is a gallium-68 complex with a prostate-specific membrane antigen targeting ligand, also known by the synonym Prostamedix.

Which organizations hold the most patents related to GaPSMA?

Progenics Pharmaceuticals Inc leads with 19 patents, followed by Cornell University with 16 patents and Deutsches Krebsforschungszentrum DKFZ with 10 patents. Novartis AG holds 9 patents, and Johns Hopkins University holds 8 patents in this area.

Who are the most prolific researchers publishing on GaPSMA?

Matthias Eiber from Technical University of Munich is the leading author with 37 papers, followed by Ali Afshar‐Oromieh from University Hospital Heidelberg with 29 papers. Jérémie Calais from University of California, Los Angeles has published 24 papers, and Wolfgang P. Fendler from Essen University Hospital has 21 papers on this compound.

What patent classifications are most common for GaPSMA-related intellectual property?

The dominant patent classifications are A61K (194 patents) covering pharmaceutical preparations, followed by A61P (138 patents) for therapeutic applications. Chemical synthesis classifications C07D (66 patents) and C07B (61 patents) are also frequently represented, along with biomedical imaging classification G06T (40 patents).

How has research activity on GaPSMA evolved in recent years?

Patent activity has shown steady growth, with 48 patents in 2022, 53 in 2023, and 55 in 2024, reaching 72 in 2025. Academic publication peaked in 2019 with 160 papers, then declined to 75 papers in 2023 before recovering to 107 papers in 2024. The most highly cited paper on this compound has 418 citations.

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