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Gallium Ga-68 gozetotide

2-[[5-[3-[[6-[[(5S)-5-carboxy-5-[[(1S)-1,3-dicarboxypropyl]carbamoylamino]pentyl]amino]-6-oxohexyl]amino]-3-oxopropyl]-2-oxidophenyl]methyl-[2-[[5-(2-carboxyethyl)-2-oxidophenyl]methyl-(carboxylatomethyl)amino]ethyl]amino]acetate;gallium-68(3+);hydron · also: GaPSMA, Ga PSMA, Prostamedix, (68)Ga-PSMA, 68Ga-Psma-11, Ga-68 PSMA-11

FormulaC44H59GaN6O17
Mol. weight1013.704
PubChem CID154572876
InChIKeyAEBYHKKMCWUMKX-LNTZDJBBSA-K
SMILES[H+].C1=CC(=C(C=C1CCC(=O)NCCCCCC(=O)NCCCC[C@@H](C(=O)O)NC(=O)N[C@@H](CCC(=O)O)C(=O)O)CN(CCN(CC2=C(C=CC(=C2)CCC(=O)O)[O-])CC(=O)[O-])CC(=O)[O-])[O-].[68Ga+3]
240Patents
1,122Research papers
162Patents - last 3 years
217Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Progenics Pharmaceuticals Inc19
2Cornell University16
3German Cancer Research Center10
4Novartis AG9
5Johns Hopkins University8
6Albert Ludwigs Universität Freiburg7
7University of California, San Diego7
8Curium US LLC6
9Amgen Inc5
10The University of Texas System4

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations194
2A61PTherapeutic activity (drug indications)138
3C07DHeterocyclic compounds66
4C07BGeneral methods of organic chemistry61
5C07KPeptides44
6G06T40
7A61B33
8C07FOrganometallic compounds31
9G16HDigital health, healthcare informatics29
10C07CAcyclic and carbocyclic compounds26

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Prostate Cancer Treatment and Research9
2Glioma Diagnosis and Treatment1
3Radiopharmaceutical Chemistry and Applications1
4Renal cell carcinoma treatment1
5Sarcoidosis and Beryllium Toxicity Research1
6Thyroid Cancer Diagnosis and Treatment1

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Matthias EiberTechnical University of Munich41
2Ali Afshar‐OromiehUniversity Hospital Heidelberg29
3Jérémie CalaisUniversity of California, Los Angeles26
4Wolfgang P. FendlerEssen University Hospital23
5Benedikt KranzbühlerUniversity of Zurich10
6Boris HadaschikEssen University Hospital19
7Louise EmmettSt Vincent's Hospital Sydney18
8Francesco CeciUniversity of Bologna16
9Uwe HaberkornHeidelberg University15
10Andrea FarolfiUniversity of Bologna14

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Gallium Ga-68 gozetotide?

Gallium Ga-68 gozetotide has the molecular formula C44H59GaN6O17 with a molecular weight of 1013.704. Its systematic name is 2-[[5-[3-[[6-[[(5S)-5-carboxy-5-[[(1S)-1,3-dicarboxypropyl]carbamoylamino]pentyl]amino]-6-oxohexyl]amino]-3-oxopropyl]-2-oxidophenyl]methyl-[2-[[5-(2-carboxyethyl)-2-oxidophenyl]methyl-(carboxylatomethyl)amino]ethyl]amino]acetate;gallium-68(3+);hydron, with InChI Key AEBYHKKMCWUMKX-LNTZDJBBSA-K.

Which organizations hold the most patents related to Gallium Ga-68 gozetotide?

The leading patent assignees are Progenics Pharmaceuticals Inc with 19 patents, Cornell University with 16 patents, and German Cancer Research Center with 10 patents. Other significant assignees include Novartis AG with 9 patents and Johns Hopkins University with 8 patents.

What are the primary clinical applications documented in the literature?

The research literature predominantly focuses on prostate cancer diagnosis and treatment. Notable studies include work on diagnostic accuracy for pelvic nodal metastasis detection, comparative efficacy analyses, and multiparametric imaging approaches. Research has also documented applications in detecting nonprostatic diseases and biochemical recurrence after radical prostatectomy.

Who are the leading researchers publishing on this compound?

The most prolific authors include Matthias Eiber from Technical University of Munich with 41 papers, Ali Afshar-Oromieh from University Hospital Heidelberg with 29 papers, and Jérémie Calais from University of California, Los Angeles with 26 papers. Other prominent researchers include Wolfgang P. Fendler and Boris Hadaschik from Essen University Hospital.

What is the current research activity trend for this compound?

Patent activity has shown growth, with 162 patents filed in the last 3 years out of 240 total patents. Publications peaked between 2018 and 2020 with 130-162 papers annually, with 217 papers published in the last 3 years out of 1122 total. The primary patent classification is A61K (medicinal chemistry) with 194 patents, followed by A61P (pharmaceutical preparations) with 138 patents.

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