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Riboflavin 5'-phosphate sodium

sodium;[(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate;dihydrate · also: FMN-Na · Photrexa · Photrexa (TN) · Phosphated riboflavin · Sodium Riboflavin Phosphate · riboflavin sodium phosphate

FormulaC17H24N4NaO11P
Mol. weight514.3595
PubChem CID23687712
InChIKeyLQVGUKOCMOKKJU-QPVGXXQTSA-M
SMILESCC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](COP(=O)(O)[O-])O)O)O.O.O.[Na+]
121Patents
3,116Research papers3,113 indexed in detail
31Patents - last 3 years
89Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Eisai Co Ltd16
2Rohto Pharmaceutical Co Ltd12
3Glaukos Corp7
4Imperial Brands PLC7
5Ajinomoto Co Inc6
6Resonac Holdings Corp6
7Daiichi Sankyo Co Ltd4
8Hisamitsu Pharmaceutical Co Inc4
9Arturus Capital Ltd3
10Chinese University of Hong Kong3

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations54
2A61PTherapeutic activity (drug indications)42
3C07DHeterocyclic compounds24
4A23LFoods and beverages (general)12
5G01NInvestigating / analysing materials12
6A23VFoods, foodstuffs - indexing scheme11
7A61N8
8A61QCosmetics, personal care8
9A01NPreservation of bodies; biocides; pest repellents6
10A24B6

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
MEDICINAL COMPOSITION2006Eisai Co Ltd68
NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1)2005Eisai Co Ltd45
NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (2)2005Eisai Co Ltd42
Tofacitinib citrate pharmaceutical composition201714
Skin color-improving agent and composition for improving skin color2017Resonac Holdings Corp12

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
201651
201762
201862
201965
202047
202145
202252
202330
202444
202515

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Gordon TollinUniversity of Arizona37
2Stephen G. MayhewUniversity College Dublin35
3Vincent MasseyUniversity of Michigan21
4J. Woodland HastingsHarvard University20
5Franz MüllerGraduate School Experimental Plant Sciences18
6Nigel S. ScruttonUniversity of Manchester18
7Changjian FengUniversity of New Mexico17
8David LeysUniversity of Manchester16
9Donald B. McCormickCornell University16
10Marta Martínez‐JúlvezUniversidad de Zaragoza12

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Riboflavin 5'-phosphate sodium?

Riboflavin 5'-phosphate sodium has the molecular formula C17H24N4NaO11P and a molecular weight of 514.3595 g/mol.

Which organizations hold the most patents involving this compound?

Eisai Co Ltd leads with 16 patents, followed by Rohto Pharmaceutical Co Ltd with 12 patents, and Glaukos Corp and Imperial Brands PLC each with 7 patents.

What is the trend in patent filings for this compound in recent years?

Patent activity has increased significantly, with 13 patents filed in 2025, 11 in 2024, and 9 in 2023. The three-year coverage (2022-2024) shows 31 patents out of 121 total patents on record.

Which author has published the most papers on this compound?

Gordon Tollin from the University of Arizona has published the most papers on this compound with 37 publications, followed by Stephen G. Mayhew from University College Dublin with 35 papers.

What are the primary patent classification codes associated with this compound?

The compound is classified primarily under A61K (54 patents), A61P (42 patents), and C07D (24 patents), indicating applications in medicinal and pharmaceutical formulations as well as organic chemistry.

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