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Riboflavin 5'-phosphate sodium

sodium;[(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate;dihydrate · also: FMN-Na, Photrexa, Photrexa (TN), Phosphated riboflavin, Sodium Riboflavin Phosphate, riboflavin sodium phosphate

FormulaC17H24N4NaO11P
Mol. weight514.3595
PubChem CID23687712
InChIKeyLQVGUKOCMOKKJU-QPVGXXQTSA-M
SMILESCC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](COP(=O)(O)[O-])O)O)O.O.O.[Na+]
121Patents
3,116Research papers
32Patents - last 3 years
89Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Eisai R&D Management Co Ltd13
2Rohto Pharmaceutical Co Ltd12
3Avedro Inc7
4Imperial Tobacco Ltd7
5Ajinomoto Co Inc6
6Resonac Holdings Corp6
7Daiichi Sankyo Healthcare Co Ltd4
8Eisai Co Ltd4
9Hisamitsu Pharmaceutical Co Inc4
10Chelsea Technologies Ltd3

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations54
2A61PTherapeutic activity (drug indications)42
3C07DHeterocyclic compounds24
4A23LFoods and beverages (general)12
5G01NInvestigating / analysing materials12
6A23VFoods, foodstuffs - indexing scheme11
7A61N8
8A61QCosmetics, personal care8
9A01NPreservation of bodies; biocides; pest repellents6
10A24B6

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Photosynthetic Processes and Mechanisms11
2bioluminescence and chemiluminescence research11
3Amino Acid Enzymes and Metabolism8
4Enzyme Structure and Function6
5Pharmacogenetics and Drug Metabolism6
6Metabolism and Genetic Disorders4
7Nitric Oxide and Endothelin Effects4
8Polyamine Metabolism and Applications4
9Light effects on plants3
10Molecular Sensors and Ion Detection3

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Gordon TollinUniversity of Arizona37
2Stephen G. MayhewUniversity College Dublin35
3Adelbert BacherTechnical University of Munich25
4Vincent MasseyUniversity of Michigan21
5J. Woodland HastingsHarvard University20
6Nigel S. ScruttonUniversity of Manchester18
7Changjian FengUniversity of New Mexico17
8Donald B. McCormickCornell University16
9Franz MüllerGraduate School Experimental Plant Sciences14
10Andrew W. MunroUniversity of Strathclyde12

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Riboflavin 5'-phosphate sodium?

Riboflavin 5'-phosphate sodium has the molecular formula C17H24N4NaO11P and a molecular weight of 514.3595 g/mol. It is also known by several alternative names including FMN-Na, Photrexa, and Flavin mononucleotide dihydrate.

Which organizations hold the most patents for Riboflavin 5'-phosphate sodium?

Eisai R&D Management Co Ltd holds the most patents with 13, followed by Rohto Pharmaceutical Co Ltd with 12 patents. Avedro Inc and Imperial Tobacco Ltd each hold 7 patents. Other significant patent holders include Ajinomoto Co Inc and Resonac Holdings Corp, each with 6 patents.

What research topics are most frequently associated with Riboflavin 5'-phosphate sodium in the literature?

Photosynthetic Processes and Mechanisms and bioluminescence and chemiluminescence research are the most prominent topics, each appearing in 11 papers. Amino Acid Enzymes and Metabolism appears in 8 papers, followed by Enzyme Structure and Function and Pharmacogenetics and Drug Metabolism, each with 6 papers.

What is the patent classification distribution for Riboflavin 5'-phosphate sodium?

The primary patent classifications are A61K with 54 patents and A61P with 42 patents, indicating pharmaceutical preparations and medical uses. C07D follows with 24 patents, relating to organic chemistry. A23L and G01N each have 12 patents, covering food applications and analytical methods respectively.

How has patent and paper activity for Riboflavin 5'-phosphate sodium changed in recent years?

Patent activity has increased significantly, with 11 patents filed in 2024 and 13 in 2025, compared to just 1-5 patents annually from 2016 to 2021. Paper publication has remained relatively steady, ranging from 30 to 65 papers per year between 2016 and 2024, with 44 papers published in 2024.

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