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FH535

2,5-dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide · also: N-(2-Methyl-4-nitrophenyl)-2,5-dichlorobenzenesulfonamide · 2,5-dichloro-N-(2-methyl-4-nitrophenyl)-benzenesulfonamide · 2,5-dichloro-N-(2-methyl-4-nitro-phenyl)benzenesulfonamide · 2,5-dichloro-N-(2-methyl-4-nitrophenyl)benzene-1-sulfonamide

FormulaC13H10Cl2N2O4S
Mol. weight361.193
PubChem CID3463933
InChIKeyAXNUEXXEQGQWPA-UHFFFAOYSA-N
SMILESCC1=C(C=CC(=C1)[N+](=O)[O-])NS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl
298Patents
51Research papers
155Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Fujifilm Holdings Corp28
2Government of the United States of America19
3Leland Stanford Junior University18
4Cincinnati Children's Hospital Medical Center14
5Kyoto University8
6RIKEN8
7Centre National de la Recherche Scientifique6
8Genus PLC6
9Sumitomo Chemical Co Ltd6
10Mass General Brigham Inc5

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C12NMicroorganisms, enzymes209
2A61KMedicinal preparations163
3A61PTherapeutic activity (drug indications)129
4G01NInvestigating / analysing materials65
5C07KPeptides43
6A61LSterilising / disinfecting materials29
7C12QMeasuring/testing involving enzymes24
8Y02AClimate change adaptation17
9C08LPolymer compositions (blends)12
10A01K9

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssignee
Application of FH535 as medicine for promoting differentiation of ADSCs into liver cells2024

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20165
20175
20185
20195
20203
20212
20221
20242
20251

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Roberto GedalyUniversity of Kentucky6
2Brett T. SpearUniversity of Kentucky5
3Jieyun JiangUniversity of Kentucky3
4David S. WattUniversity of Kentucky3
5Vitaliy M. SviripaUniversity of Kentucky2
6Stefano GianniIstituto Pasteur2
7Fei‐Ran GongSoochow University2
8Alexis GrandeUniversity of Modena and Reggio Emilia2
9Roberto GaluppoUniversity of Kentucky2
10Chunsheng KangTianjin Medical University General Hospital2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of FH535?

FH535 has the molecular formula C13H10Cl2N2O4S and a molecular weight of 361.193.

Which organizations hold the most patents related to FH535?

The leading patent assignees for FH535 are Fujifilm Holdings Corp with 28 patents, Government of the United States of America with 19 patents, and Leland Stanford Junior University with 18 patents.

What research areas are most commonly associated with FH535 patents?

FH535-related patents are predominantly classified under C12N (209 patents), A61K (163 patents), and A61P (129 patents), indicating focus on biotechnology, pharmaceutical compounds, and therapeutic applications.

How has publication and patent activity for FH535 changed in recent years?

Patent activity for FH535 has grown significantly, with 80 patents filed in 2024 and 45 in 2025. Paper publication has declined, with only 3 papers in the last three years compared to 5 papers annually in earlier periods (2016–2019).

What is the primary research focus of leading FH535 authors?

Roberto Gedaly from University of Kentucky is the most prolific author with 6 papers on FH535, followed by Brett T. Spear from University of Kentucky with 5 papers. Research topics include Wnt/β-catenin signaling pathway inhibition and its effects on cancer stem cells and hepatocellular carcinoma.

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