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Protoporphyrin disodium

disodium;3-[18-(2-carboxylatoethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate · also: Dojin PM, Palepron, Protoporphyrin sodium, Disodium protoporphyrin, Protoporphyrin IX disodium, Protoporphyrin sodium salt

FormulaC34H32N4Na2O4
Mol. weight606.6335
PubChem CID71484
InChIKeyGPRXGEKBQVXWAQ-UHFFFAOYSA-L
SMILESCC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C=C)C)C(=C4CCC(=O)[O-])C)C(=C3C)CCC(=O)[O-])C=C.[Na+].[Na+]
385Patents
2,259Research papers
43Patents - last 3 years
134Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Ono Pharmaceutical Co Ltd67
2Fate Therapeutics Inc13
3Fuji Chemical Industries Co Ltd12
4Sankyo Co Ltd10
5Sanofi Pasteur Inc9
6Sanofi Vaccines US Inc9
7Asahi Kasei Pharma Corp7
8Sanofi Pasteur SA7
9SBI Pharmaceuticals Co Ltd6
10Sanwa Kagaku Kenkyusho Co Ltd6

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)184
2A61KMedicinal preparations175
3C07DHeterocyclic compounds109
4G01NInvestigating / analysing materials52
5C12NMicroorganisms, enzymes44
6Y02AClimate change adaptation37
7C12PFermentation, enzyme processes17
8Y10TCross-reference (technical subjects)17
9Y10SCross-reference (legacy)16
10C07HSugars and derivatives15

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Process for preparing protoporphyrin disodium salt2003SHANGHAI JINCHI BIOLOGICAL PRODUCTS CO., LTD.3
PRODUCTION OF PROTOPORPHYRIN DISODIUM SALT1988SSP Co Ltd2
A kind of preparation method of protoporphyrin disodium2018HUAZHONG AGRICULTURAL UNIVERSITY0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Photodynamic Therapy Research Studies31
2Nanoplatforms for cancer theranostics7
3Heme Oxygenase-1 and Carbon Monoxide6
4Porphyrin Metabolism and Disorders6
5Porphyrin and Phthalocyanine Chemistry3
6Hemoglobin structure and function2
7Advanced Fluorescence Microscopy Techniques1
8Click Chemistry and Applications1
9DNA Repair Mechanisms1
10Dermatologic Treatments and Research1

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Johan MoanNorwegian Cancer Society50
2Tayyaba HasanMassachusetts General Hospital24
3Asta JuzenieneNorwegian Cancer Society19
4Hans Christian WulfBispebjerg Hospital19
5Alexander J. MacRobertUniversity College London17
6Pan WangShaanxi Normal University16
7Petras JuzenasNorwegian Cancer Society16
8Brian W. PogueDartmouth College15
9Norbert LangeÉcole Polytechnique Fédérale de Lausanne15
10Qian PengOslo University Hospital14

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Protoporphyrin disodium?

Protoporphyrin disodium has the molecular formula C34H32N4Na2O4 with a molecular weight of 606.6335. It is also known by the systematic name disodium;3-[18-(2-carboxylatoethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate.

Which organizations hold the most patents for Protoporphyrin disodium?

Ono Pharmaceutical Co Ltd leads with 67 patents, followed by Fate Therapeutics Inc with 13 patents and Fuji Chemical Industries Co Ltd with 12 patents. Other significant patent holders include Sankyo Co Ltd with 10 patents and Sanofi Pasteur Inc with 9 patents.

What are the main research topics associated with Protoporphyrin disodium?

Photodynamic Therapy Research Studies is the dominant topic with 31 papers, followed by Nanoplatforms for cancer theranostics with 7 papers and Porphyrin Metabolism and Disorders with 6 papers. Other research areas include Heme Oxygenase-1 and Carbon Monoxide, and Porphyrin and Phthalocyanine Chemistry.

Who are the most prolific authors publishing on Protoporphyrin disodium?

Johan Moan from the Norwegian Cancer Society leads with 50 papers, followed by Tayyaba Hasan from Massachusetts General Hospital with 24 papers. Other active researchers include Asta Juzeniene and Hans Christian Wulf, each with 19 papers, and Alexander J. MacRobert from University College London with 17 papers.

What is the coverage of Protoporphyrin disodium in the scientific and patent literature?

The compound is covered by 385 total patents with 43 patents filed in the last 3 years. The scientific literature includes 2,259 papers from journal matching, with 134 papers published in the last 3 years, demonstrating sustained research activity in recent periods.

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