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Protoporphyrin disodium

disodium;3-[18-(2-carboxylatoethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate · also: Dojin PM · Palepron · Protoporphyrin sodium · Disodium protoporphyrin · Protoporphyrin IX disodium · Protoporphyrin sodium salt

FormulaC34H32N4Na2O4
Mol. weight606.6335
PubChem CID71484
InChIKeyGPRXGEKBQVXWAQ-UHFFFAOYSA-L
SMILESCC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C=C)C)C(=C4CCC(=O)[O-])C)C(=C3C)CCC(=O)[O-])C=C.[Na+].[Na+]
385Patents
2,259Research papers2,262 indexed in detail
41Patents - last 3 years
134Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Ono Pharmaceutical Co Ltd67
2Fate Therapeutics Inc13
3Fuji Chemical Industries Co Ltd12
4Daiichi Sankyo Co Ltd10
5Sanofi SA9
6Chinese Academy of Sciences8
7Asahi Kasei Corp7
8SBI Holdings Inc6
9Suzuken Co Ltd6
10Commissariat à l'Énergie Atomique et Aux Énergies Alternatives5

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)184
2A61KMedicinal preparations175
3C07DHeterocyclic compounds109
4G01NInvestigating / analysing materials52
5C12NMicroorganisms, enzymes44
6Y02AClimate change adaptation37
7C12PFermentation, enzyme processes17
8Y10TCross-reference (technical subjects)17
9Y10SCross-reference (legacy)16
10C07HSugars and derivatives15

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Process for preparing protoporphyrin disodium salt20033
PRODUCTION OF PROTOPORPHYRIN DISODIUM SALT1988Sanofi SA2
A kind of preparation method of protoporphyrin disodium20180

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
201697
201777
201883
201994
202065
202160
202221
202319
202477
202538

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Johan MoanNorwegian Cancer Society38
2Tayyaba HasanMassachusetts General Hospital24
3Hans Christian WulfBispebjerg Hospital19
4Vladimir IaniNorwegian Cancer Society18
5Petras JuzenasNorwegian Cancer Society16
6Norbert LangeÉcole Polytechnique Fédérale de Lausanne15
7Asta JuzenieneNorwegian Cancer Society14
8Qian PengOslo University Hospital14
9Brian W. PogueDartmouth College14
10Georges WagnièresÉcole Polytechnique Fédérale de Lausanne12

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Protoporphyrin disodium?

Protoporphyrin disodium has the molecular formula C34H32N4Na2O4 with a molecular weight of 606.6335. Its canonical chemical name is disodium;3-[18-(2-carboxylatoethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate.

Which organizations hold the most patents related to Protoporphyrin disodium?

Ono Pharmaceutical Co Ltd leads with 67 patents, followed by Fate Therapeutics Inc with 13 patents and Fuji Chemical Industries Co Ltd with 12 patents. Other significant patent holders include Daiichi Sankyo Co Ltd with 10 patents and Sanofi SA with 9 patents.

What are the dominant patent classifications for Protoporphyrin disodium?

The most common patent classifications are A61P (184 patents), covering pharmaceutical preparations, and A61K (175 patents), covering medicinal preparations. These are followed by C07D (109 patents) for heterocyclic compounds and G01N (52 patents) for investigating or analyzing materials.

Who are the most prolific authors publishing on Protoporphyrin disodium?

Johan Moan from Norwegian Cancer Society has authored the most papers with 38 publications, followed by Tayyaba Hasan from Massachusetts General Hospital with 24 papers. Other leading authors include Hans Christian Wulf from Bispebjerg Hospital (19 papers), Vladimir Iani from Norwegian Cancer Society (18 papers), and Petras Juzenas from Norwegian Cancer Society (16 papers).

What is the research publication trend for Protoporphyrin disodium in recent years?

Paper publication shows significant activity in 2024 with 77 papers, while 2025 has 38 papers to date. Patent activity has increased notably, with 25 patents filed in 2024 and 14 in 2025, compared to the 2022-2023 average of roughly 12-13 patents per year. Overall coverage includes 2,262 papers and 385 total patents.

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