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Degalol

(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid · also: Kybella, Droxolan, Pyrochol, Septochol, Cholorebic, Cholerebic

FormulaC24H40O4
Mol. weight392.58
PubChem CID222528
InChIKeyKXGVEGMKQFWNSR-LLQZFEROSA-N
SMILESC[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
90,391Patents
8,536Research papers
6,785Patents - last 3 years
145Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Alnylam Pharmaceuticals Inc1,334
2Human Genome Sciences Inc966
3Ionis Pharmaceuticals Inc838
4Fujifilm Corp831
5GlaxoSmithKline Biologicals SA791
6University of California San Diego UCSD767
7Novartis AG647
8Takeda Pharmaceutical Co Ltd578
9Novo Nordisk AS466
10Procter and Gamble Co459

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations54,955
2A61PTherapeutic activity (drug indications)49,129
3C07KPeptides24,677
4C12NMicroorganisms, enzymes23,899
5G01NInvestigating / analysing materials14,053
6C07DHeterocyclic compounds8,654
7C12QMeasuring/testing involving enzymes8,485
8Y02AClimate change adaptation6,041
9Y10SCross-reference (legacy)3,988
10C12YEnzyme nomenclature (EC numbers)3,707

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
A kind of Septochol base-oxidation Curdlan polysaccharide nanoparticle and preparation method2016JIANGSU UNIVERSITY0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Drug Transport and Resistance Mechanisms29
2HIV Research and Treatment5
3Antifungal resistance and susceptibility4
4Bacteriophages and microbial interactions4
5Gallbladder and Bile Duct Disorders4
6Lipid Membrane Structure and Behavior4
7Monoclonal and Polyclonal Antibodies Research4
8Prion Diseases and Protein Misfolding4
9Enzyme Catalysis and Immobilization3
10Gastrointestinal motility and disorders3

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Youngro ByunSeoul National University34
2Alan F. HofmannUniversity of California San Diego31
3Junichi GotoTohoku University15
4Harris BernsteinUniversity of Arizona14
5A. StiehlHeidelberg University12
6Carol BernsteinUniversity of Arizona12
7Claire M. PayneUniversity of Arizona10
8Aldo RodaUniversity of Bologna10
9R. H. DowlingGuy's Hospital10
10Hyun Tae MoonGS Caltex (South Korea)9

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

TitleYearCited byTopic
Assay of proteins in the presence of interfering materials19763205Mass Spectrometry Techniques and Applications
Solubilization of membranes by detergents19752935Lipid Membrane Structure and Behavior
Identification of a Nuclear Receptor for Bile Acids19992674Drug Transport and Resistance Mechanisms
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome20132185Gut microbiota and health
lincRNAs act in the circuitry controlling pluripotency and differentiation20111897MicroRNA in disease regulation

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Degalol?

Degalol has the molecular formula C24H40O4 with a molecular weight of 392.58 g/mol. Its canonical IUPAC name is (4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid.

What are common synonyms for Degalol?

Degalol is known by many synonyms including Kybella, Droxolan, Pyrochol, Septochol, deoxycholate, deoxycholic acid, and sodium deoxycholate, among others. The compound is also referred to as Ursodeoxycholic Acid EP Impurity E.

Which research topics are most associated with Degalol in the literature?

The most prominent research topics associated with Degalol include Drug Transport and Resistance Mechanisms (29 papers), Gallbladder and Bile Duct Disorders (4 papers), and Lipid Membrane Structure and Behavior (4 papers). Additional topics include gastrointestinal motility and disorders, and enzyme catalysis and immobilization.

What are the leading research institutions and organizations studying Degalol?

Leading academic contributors include researchers at Seoul National University, University of California San Diego, Tohoku University, University of Arizona, and Heidelberg University. The most prolific individual authors on Degalol-related topics are Youngro Byun from Seoul National University (34 papers) and Alan F. Hofmann from University of California San Diego (31 papers).

How is Degalol patent activity distributed across technology classifications?

Patent activity related to Degalol is concentrated in pharmaceutical and biotechnology classifications. The leading CPC subclasses are A61K (Preparations for medical purposes, 54,955 patents), A61P (Drugs for specific diseases, 49,129 patents), and C07K (Peptides and proteins, 24,677 patents). Overall, 90,391 patents reference Degalol across all technologies.

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