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Deoxycholic Acid

(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid · also: 3alpha · Degalol · Kybella · Pyrochol · Droxolan · Septochol

FormulaC24H40O4
Mol. weight392.58
PubChem CID222528
InChIKeyKXGVEGMKQFWNSR-LLQZFEROSA-N
SMILESC[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
90,391Patents
8,536Research papers8,542 indexed in detail
6,080Patents - last 3 years
145Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Alnylam Pharmaceuticals Inc1,334
2Novartis AG1,154
3Fujifilm Holdings Corp1,152
4Samsung Biologics Co Ltd979
5Roche Holding AG960
6University of California909
7Ionis Pharmaceuticals Inc856
8Merck and Co Inc837
9GSK PLC802
10Takeda Pharmaceutical Co Ltd634

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations54,974
2A61PTherapeutic activity (drug indications)49,146
3C07KPeptides24,680
4C12NMicroorganisms, enzymes23,909
5G01NInvestigating / analysing materials14,058
6C07DHeterocyclic compounds8,654
7C12QMeasuring/testing involving enzymes8,486
8Y02AClimate change adaptation6,042
9Y10SCross-reference (legacy)3,990
10C12YEnzyme nomenclature (EC numbers)3,716

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Process for preparing 3alpha(beta)-7alpha(beta)-dihydroxy-6alpha(beta)-alkyl-5beta-cholanic acid2008Alfasigma SpA63
3alpha, 9alpha-epoxy steroids of the androstane and pregnane series1962Pfizer Inc31
Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits2014AbbVie Inc29
Formulations of deoxycholic acid and salts thereof2013AbbVie Inc25
Formulations of deoxycholic acid and salts thereof2012AbbVie Inc25

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
201696
2017123
201897
2019107
202086
202174
202261
202354
202459
202532

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Youngro ByunSeoul National University36
2Alan F. HofmannUniversity of California San Diego27
3Junichi GotoTohoku University15
4Harris BernsteinUniversity of Arizona14
5Carol BernsteinUniversity of Arizona12
6Aldo RodaUniversity of Bologna10
7R. H. DowlingGuy's Hospital10
8Hyun Tae MoonGS Caltex (South Korea)9
9U. LeuschnerGoethe University Frankfurt9
10Thomas A. MillerVirginia Commonwealth University Medical Center8

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

TitleYearCited byTopic
Assay of proteins in the presence of interfering materials19763207Mass Spectrometry Techniques and Applications
Solubilization of membranes by detergents19752943Lipid Membrane Structure and Behavior
Identification of a Nuclear Receptor for Bile Acids19992703Drug Transport and Resistance Mechanisms
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome20132216Gut microbiota and health
lincRNAs act in the circuitry controlling pluripotency and differentiation20111908MicroRNA in disease regulation

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Deoxycholic Acid?

Deoxycholic Acid has the molecular formula C24H40O4 and a molecular weight of 392.58.

Which organizations have the most patents related to Deoxycholic Acid?

The top patent assignees in the Deoxycholic Acid space are Alnylam Pharmaceuticals Inc with 1334 patents, Novartis AG with 1154 patents, and Fujifilm Holdings Corp with 1152 patents.

Who are the most prolific researchers publishing on Deoxycholic Acid?

Youngro Byun from Seoul National University is the most prolific author with 36 papers, followed by Alan F. Hofmann from University of California San Diego with 27 papers, and Junichi Goto from Tohoku University with 15 papers.

What are the primary patent classification areas for Deoxycholic Acid inventions?

The most common CPC subclasses associated with Deoxycholic Acid patents are A61K (54974 patents), A61P (49146 patents), and C07K (24680 patents), indicating focus on pharmaceutical preparations, medicinal uses, and protein chemistry.

How has research publication activity on Deoxycholic Acid changed over recent years?

Publication activity on Deoxycholic Acid has declined overall in recent years, with 96 papers in 2016 decreasing to 59 papers in 2024, and 32 papers recorded in 2025 so far.

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