Who owns the IP
The organizations most actively patenting around this compound, ranked by referenced patent volume.
| # | Assignee | Patents |
|---|---|---|
| 1 | Chinese Academy of Sciences | 10 |
| 2 | Chinese Academy of Medical Sciences & Peking Union Medical College | 3 |
| 3 | Xel Pharmaceuticals Inc | 3 |
| 4 | Zhejiang University | 3 |
| 5 | Institute of Chinese Materia Medica of China Academy of Chinese Medical Sciences | 2 |
| 6 | Zhejiang Chinese Medical University | 2 |
| 7 | China Traditional Chinese Medicine Holdings Co Ltd | 1 |
| 8 | Jiyang College of Zhejiang A&F University | 1 |
| 9 | Shimadzu Corp | 1 |
Explore the full landscape
This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.
Visit CyprisWhere innovation is concentrated
Patent classifications ranked by volume reveal the technical domains with the most active filing.
| # | Code | Area | Patents |
|---|---|---|---|
| 1 | A61K | Medicinal preparations | 68 |
| 2 | A61P | Therapeutic activity (drug indications) | 54 |
| 3 | C07D | Heterocyclic compounds | 32 |
| 4 | G01N | Investigating / analysing materials | 10 |
| 5 | Y02A | Climate change adaptation | 6 |
| 6 | A61Q | Cosmetics, personal care | 4 |
| 7 | A23L | Foods and beverages (general) | 3 |
| 8 | A23V | Foods, foodstuffs - indexing scheme | 3 |
| 9 | C07B | General methods of organic chemistry | 3 |
| 10 | C07C | Acyclic and carbocyclic compounds | 3 |
AI mapped opportunity space
This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.
See Cypris in actionRepresentative patents
The filings that best characterise the patent activity around this compound, most-referenced first.
| Title | Year | Assignee | Cited by |
|---|---|---|---|
| Corydalis B long-acting preparation and its preparing method | 2005 | 5 | |
| Application of the tetrahydropalmatine in anti-toxicity of cisplatin medicine is prepared | 2017 | Zhejiang University | 4 |
| Levo-tetrahydropalmatine transdermal drug delivery preparation | 2011 | 4 | |
| Application of tetrahydropalmatine enantiomers in preparation of P-glycoprotein inhibitor | 2011 | Zhejiang University | 4 |
| A kind of extracting method of tetrahydropalmatine | 2019 | 2 |
How research activity has moved
Papers published per year for this compound, over the last decade of indexed records.
| Year | Papers |
|---|---|
| 2016 | 19 |
| 2017 | 10 |
| 2018 | 10 |
| 2019 | 8 |
| 2020 | 12 |
| 2021 | 20 |
| 2022 | 5 |
| 2023 | 9 |
| 2024 | 6 |
| 2025 | 5 |
Who's driving the science
The most-published authors working with this compound, alongside their primary affiliations.
| # | Author | Affiliation | Papers |
|---|---|---|---|
| 1 | Yifeng Chai | Second Military Medical University | 8 |
| 2 | Huidi Jiang | Zhejiang University | 7 |
| 3 | Zhanying Hong | Second Military Medical University | 7 |
| 4 | Guo-Zhang Jin | Shanghai Institute of Materia Medica | 7 |
| 5 | Shi‐Jiang Li | Medical College of Wisconsin | 6 |
| 6 | Xueping Yin | Second Military Medical University | 5 |
| 7 | Hongliang Su | Shanxi Medical University | 5 |
| 8 | H. Bun | Aix-Marseille Université | 4 |
| 9 | Sok‐Siya Bun | Aix-Marseille Université | 4 |
| 10 | Évelyne Ollivier | Aix-Marseille Université | 4 |
Research leaders
This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.
See Cypris in actionThe literature that defines it
The most-cited papers anchoring the scientific record for this compound.
| Title | Year | Cited by | Topic |
|---|---|---|---|
| Protective effect of tetrahydropalmatine against d-galactose induced memory impairment in rat | 2015 | 121 | Antioxidants, Aging, Portulaca oleracea |
| Determination of dl-tetrahydropalmatine in Corydalis yanhusuo by l-tetrahydropalmatine imprinted monolithic column coupling with reversed-phase high performance liquid chromatography | 2006 | 118 | Analytical chemistry methods development |
| The Clinical Spectrum of Jin Bu Huan Toxicity | 1996 | 108 | Complementary and Alternative Medicine Studies |
| L -Tetrahydropalamatine: A Potential New Medication for the Treatment of Cocaine Addiction | 2012 | 102 | Neurotransmitter Receptor Influence on Behavior |
| Comprehensive two-dimensional HepG2/cell membrane chromatography/monolithic column/time-of-flight mass spectrometry system for screening anti-tumor components from herbal medicines | 2012 | 99 | Mass Spectrometry Techniques and Applications |
Frequently asked questions
Common questions about this compound's patent and research landscape, answered from the underlying data.
What is the molecular formula and weight of D-Tetrahydropalmatine?
Which organizations hold the most patents for D-Tetrahydropalmatine?
What are the main research topics covered in high-impact papers on D-Tetrahydropalmatine?
How has research output on D-Tetrahydropalmatine changed in recent years?
What are the primary patent classification areas for D-Tetrahydropalmatine inventions?