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Cyclopropan

cyclopropane · also: Zyklopropan, Cyclopropyl, ciclopropano, Trimethylene, Cyclopropnane, cyclopropanum

FormulaC3H6
Mol. weight42.081
PubChem CID6351
InChIKeyLVZWSLJZHVFIQJ-UHFFFAOYSA-N
SMILESC1CC1
125,552Patents
2,034Research papers
8,457Patents - last 3 years
20Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Bayer AG2,966
2Merck Sharp & Dohme LLC2,613
3BASF SE2,168
4Bayer CropScience AG2,087
5Bristol Myers Squibb Co1,977
6Novartis AG1,957
7F Hoffmann La Roche AG1,718
8Boehringer Ingelheim International GmbH1,599
9Bayer Pharma AG1,388
10Janssen Pharmaceutica NV1,327

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C07DHeterocyclic compounds80,382
2A61PTherapeutic activity (drug indications)72,015
3A61KMedicinal preparations47,447
4C07CAcyclic and carbocyclic compounds19,615
5A01NPreservation of bodies; biocides; pest repellents12,689
6C07FOrganometallic compounds8,234
7C07KPeptides5,167
8Y02PClimate change mitigation: production4,258
9C07BGeneral methods of organic chemistry4,081
10C08LPolymer compositions (blends)3,743

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method2002AstraZeneca AB394
Tetrahydronaphthyl and cyclopropyl substituted 1,3-butadienes having retinoid-like activity1994Allergan Inc102
CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR2011Auspex Pharmaceuticals Inc96
1-(BENZO [D] [1,3] DI0X0L-5-YL) -N- (PHENYL) CYCLOPROPANE- CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS FOR THE TREATMENT OF CYSTIC FIBROSIS2007Vertex Pharmaceuticals Inc95
PERFLUORINATED CYCLOPROPYL FUSED 1,3-OXAZIN-2-AMINE COMPOUNDS AS BETA-SECRETASE INHIBITORS AND METHODS OF USE2014Amgen Inc68

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Cyclopropane Reaction Mechanisms5
2Anesthesia and Neurotoxicity Research2
3Anesthesia and Sedative Agents2
4Metal complexes synthesis and properties2
5Microbial Natural Products and Biosynthesis2
6Protein Structure and Dynamics2
7Advanced Chemical Physics Studies1
8Advanced Chemical Sensor Technologies1
9Anesthesia and Pain Management1
10Asymmetric Synthesis and Catalysis1

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Armin de MeijereUniversity of Göttingen12
2Akira MatsudaHokkaido University10
3Satoshi ShutoHokkaido University9
4Ana I. JiménezUniversidad de Zaragoza7
5André B. CharetteUniversité de Montréal7
6Antonio M. EchavarrenInstitut Català d'Investigació Química6
7Michael A. KerrWestern University6
8Min ShiShanghai Institute of Organic Chemistry6
9Agnieszka MrozikUniversity of Silesia in Katowice5
10Alfred Burger5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular structure and basic chemistry of cyclopropane?

Cyclopropane (also known as Cyclopropan, Trimethylene, and other synonyms) has the molecular formula C3H6 with a molecular weight of 42.081. Its InChI Key is LVZWSLJZHVFIQJ-UHFFFAOYSA-N.

Which companies hold the most patents related to cyclopropane?

The leading assignees in cyclopropane-related patents are Bayer AG with 2966 patents, Merck Sharp and Dohme LLC with 2613 patents, and BASF SE with 2168 patents. Other major patent holders include Bayer CropScience AG, Bristol Myers Squibb Co, Novartis AG, F Hoffmann La Roche AG, Boehringer Ingelheim International GmbH, Bayer Pharma AG, and Janssen Pharmaceutica NV.

What are the major patent classification areas for cyclopropane chemistry?

The largest patent classification areas are C07D (80,379 patents), A61P (72,011 patents), and A61K (47,432 patents), followed by C07C, A01N, and C07F. These classifications indicate significant activity in organic chemistry, pharmaceuticals, and agricultural chemistry.

What are the most highly-cited scientific papers on cyclopropane?

Notable papers include 'Heterocycles from cyclopropanes: applications in natural product synthesis' (2009, 887 citations), 'Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes' (2012, 827 citations), and 'Cyclopropanation Strategies in Recent Total Syntheses' (2017, 660 citations). These papers address asymmetric synthesis and catalytic functionalization methods.

Who are the leading academic researchers publishing on cyclopropane?

Key researchers include Armin de Meijere from University of Göttingen with 12 papers, Akira Matsuda and Satoshi Shuto from Hokkaido University with 10 and 9 papers respectively, Ana I. Jiménez from Universidad de Zaragoza and André B. Charette from Université de Montréal each with 7 papers, and Antonio M. Echavarren, Michael A. Kerr, and Min Shi each with 6 papers.

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