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Cholestan-3-ol

(8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol · also: Dihydrocholesterol, Dihydrocholestenol, 3-hydroxy-cholestane, 5 alpha Cholestan 3 alpha ol

FormulaC27H48O
Mol. weight388.68
PubChem CID10992748
InChIKeyQYIXCDOBOSTCEI-BPAAZKTESA-N
SMILESC[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CCC(C4)O)C)C
6,481Patents
622Research papers
1,382Patents - last 3 years
19Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1BioNTech SE158
2Merck Sharp & Dohme LLC111
3Kao Corp101
4Lipocine Inc92
5NOF Corp90
6Kimberly Clark Worldwide Inc86
7Lion Corp85
8Harvard University76
9Fujifilm Corp72
10Elan Pharmaceuticals LLC65

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations4,656
2A61PTherapeutic activity (drug indications)3,118
3C12NMicroorganisms, enzymes1,818
4A61QCosmetics, personal care1,039
5C07KPeptides775
6C07DHeterocyclic compounds574
7C07CAcyclic and carbocyclic compounds508
8C07J377
9G01NInvestigating / analysing materials329
10C12YEnzyme nomenclature (EC numbers)282

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Preparation method of dihydrocholesterol and cholestanone2009ANHUI CHEN-BRIGHT BIOENGINEERING CO., LTD.3
Method for preparing dihydrocholesterol and cholestanone2011ANHUI CHEN-BRIGHT BIOENGINEERING CO., LTD.1
USE OF DIHYDROCHOLESTEROL2017Nestec SA0
USE OF DIHYDROCHOLESTEROL2016Nestec SA0
Method for preparing dihydrocholesterol and cholestanone2013ANHUI CHEN-BRIGHT BIOENGINEERING CO., LTD.0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Cholesterol and Lipid Metabolism9
2Lipoproteins and Cardiovascular Health3
3Analytical Chemistry and Chromatography1
4Analytical Methods in Pharmaceuticals1
5Diet, Metabolism, and Disease1
6Drug Transport and Resistance Mechanisms1
7Groundwater and Isotope Geochemistry1
8Helicobacter pylori-related gastroenterology studies1
9Microbial infections and disease research1
10Microplastics and Plastic Pollution1

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Helena GyllingUniversity of Eastern Finland18
2Antonio FedericoUniversity of Siena12
3Ingemar BjörkhemKarolinska Institutet12
4Tatu A. MiettinenUniversity of Helsinki9
5Gerald SalenUnited States Department of Veterans Affairs9
6Aad VerripsCanisius-Wilhelmina Ziekenhuis8
7Dieter LütjohannUniversity Hospital Bonn8
8Andrea E. DeBarberOregon Health & Science University7
9Andrea MignarriUniversity of Siena6
10Elisabeth NorinKarolinska Institutet6

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition and molecular identity of Cholestan-3-ol?

Cholestan-3-ol has the molecular formula C27H48O with a molecular weight of 388.68 g/mol. Its canonical IUPAC name is (8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol, and it is also known by the synonyms Dihydrocholesterol and 3-hydroxy-cholestane. The InChI Key is QYIXCDOBOSTCEI-BPAAZKTESA-N.

How extensive is the patent and research coverage for Cholestan-3-ol?

Cholestan-3-ol has substantial coverage in both patent and scientific literature. The aggregate includes 6,481 total patents and 622 papers related to this compound. In the last three years, there have been 1,382 patents and 19 papers published or filed. The patent landscape shows significant growth, with 626 patents in 2024 alone.

Which organizations hold the most patents involving Cholestan-3-ol?

The leading patent assignees for Cholestan-3-ol are BioNTech SE with 158 patents, Merck Sharp & Dohme LLC with 111 patents, Kao Corp with 101 patents, Lipocine Inc with 92 patents, and NOF Corp with 90 patents. Other significant patent holders include Kimberly Clark Worldwide Inc, Lion Corp, Harvard University, Fujifilm Corp, and Elan Pharmaceuticals LLC.

Who are the leading academic researchers publishing on Cholestan-3-ol?

The most prolific authors in the scientific literature on Cholestan-3-ol include Helena Gylling from University of Eastern Finland with 18 papers, Antonio Federico and Ingemar Björkhem each with 12 papers, Tatu A. Miettinen and Gerald Salen each with 9 papers, and Aad Verrips and Dieter Lütjohann each with 8 papers. Their work spans institutions including the University of Siena, Karolinska Institutet, University of Helsinki, and others.

What are the primary technological and research domains associated with Cholestan-3-ol?

Cholestan-3-ol patents are concentrated in pharmaceutical and biotech fields, with A61K (Medicinal preparations) leading at 4,656 patents, followed by A61P (Specific therapeutic activity) at 3,118 patents, and C12N (Microorganisms or enzymes) at 1,818 patents. Scientific research on this compound focuses primarily on Cholesterol and Lipid Metabolism, followed by Lipoproteins and Cardiovascular Health.

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