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Cholestan-3-ol

(8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol · also: Dihydrocholestenol · 3-hydroxy-cholestane · 5 alpha Cholestan 3 alpha ol

FormulaC27H48O
Mol. weight388.68
PubChem CID10992748
InChIKeyQYIXCDOBOSTCEI-BPAAZKTESA-N
SMILESC[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CCC(C4)O)C)C
6,481Patents
622Research papers618 indexed in detail
1,321Patents - last 3 years
19Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1BioNTech SE158
2Merck and Co Inc118
3Kao Corp104
4NOF Corp101
5Lipocine Inc94
6Lion Corp92
7Kimberly Clark Corp88
8Harvard University76
9Fujifilm Holdings Corp72
10Precision Biosciences Inc70

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations4,663
2A61PTherapeutic activity (drug indications)3,122
3C12NMicroorganisms, enzymes1,823
4A61QCosmetics, personal care1,039
5C07KPeptides783
6C07DHeterocyclic compounds574
7C07CAcyclic and carbocyclic compounds508
8C07J377
9G01NInvestigating / analysing materials329
10C12YEnzyme nomenclature (EC numbers)290

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions20011,763
IMPROVED AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS2010Arbutus Biopharma Corp682
Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents2002986
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions2005Lipocine Inc833
Solid carriers for improved delivery of hydrophobic active ingredients in pharmaceutical compositions2003Lipocine Inc906

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20169
20179
201812
201915
20209
20217
20229
20237
202410
20252

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Helena GyllingUniversity of Eastern Finland16
2Tore MidtvedtKarolinska Institutet15
3Maarit HallikainenUniversity of Eastern Finland8
4Aad VerripsCanisius-Wilhelmina Ziekenhuis8
5Tatu A. MiettinenUniversity of Helsinki8
6Elisabeth NorinKarolinska Institutet7
7Eran LeitersdorfHadassah Medical Center6
8Sarah SheferUniversity Hospital, Newark6
9Helena GyllingUniversity of Eastern Finland6
10Gian Nicola GallusUniversity of Siena5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Cholestan-3-ol?

Cholestan-3-ol has the molecular formula C27H48O with a molecular weight of 388.68 g/mol.

How much patent activity involves Cholestan-3-ol, and what is the recent trend?

There are 6,481 total patents covering Cholestan-3-ol. Patent filings have increased significantly in recent years, with 626 patents in 2024 and 568 in 2023, compared to 155 in 2016. Over the last 3 years, 1,321 patents have been filed.

Which assignees hold the most patents related to Cholestan-3-ol?

The leading patent holders are BioNTech SE with 158 patents, Merck and Co Inc with 118 patents, Kao Corp with 104 patents, and NOF Corp with 101 patents.

What are the primary patent classification areas for Cholestan-3-ol inventions?

The largest patent classifications are A61K (4,663 patents, covering pharmaceutical compositions), A61P (3,122 patents, covering therapeutic uses), and C12N (1,823 patents, covering biotechnology methods). These account for the majority of Cholestan-3-ol-related patent activity.

What research topics are covered in academic papers about Cholestan-3-ol?

Academic papers on Cholestan-3-ol cover topics including gut microbiota and health, as in a 2020 paper on cholesterol metabolism by uncultured human gut bacteria, lipoproteins and cardiovascular health, and its role as a predictor of recurrent coronary events in Scandinavian populations.

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