Who owns the IP
The organizations most actively patenting around this compound, ranked by referenced patent volume.
| # | Assignee | Patents |
|---|---|---|
| 1 | Procter and Gamble Co | 307 |
| 2 | Henkel AG and Co KGaA | 278 |
| 3 | Kao Corp | 227 |
| 4 | Beiersdorf AG | 209 |
| 5 | L'Oréal SA | 157 |
| 6 | Suntory Holdings Ltd | 146 |
| 7 | Coca-Cola Co | 114 |
| 8 | Societe des Produits Nestle SA | 114 |
| 9 | General Foods Corp | 111 |
| 10 | Nestec SA | 86 |
Explore the full landscape
This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.
Visit CyprisWhere innovation is concentrated
Patent classifications ranked by volume reveal the technical domains with the most active filing.
| # | Code | Area | Patents |
|---|---|---|---|
| 1 | A61K | Medicinal preparations | 11,265 |
| 2 | A61P | Therapeutic activity (drug indications) | 7,124 |
| 3 | A23L | Foods and beverages (general) | 4,030 |
| 4 | A61Q | Cosmetics, personal care | 3,575 |
| 5 | A23F | Coffee, tea; their substitutes | 3,114 |
| 6 | A23V | Foods, foodstuffs - indexing scheme | 2,702 |
| 7 | C07D | Heterocyclic compounds | 1,759 |
| 8 | G01N | Investigating / analysing materials | 1,274 |
| 9 | A23G | Cocoa, chocolate, confectionery | 960 |
| 10 | C12N | Microorganisms, enzymes | 873 |
AI mapped opportunity space
This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.
See Cypris in actionMost-cited patents
Patents ranked by forward citations reveal the foundational inventions the field continues to build on.
| Title | Year | Assignee | Cited by |
|---|---|---|---|
| High-affinity nucleic acid ligands that discriminate between theophylline and caffeine | 1996 | Gilead Sciences Inc | 496 |
| Reversal of general anesthesia by administration of methylphenidate, amphetamine, modafinil, amantadine, and/or caffeine | 2019 | General Hospital Corp | 353 |
| Method for oral spray administration of caffeine | 1995 | SPECTOR; JOHN E. | 127 |
| Herbal caffeine replacement composition and food products incorporating same | 2002 | ZHOU JAMES H. | 72 |
| Composition comprising caffeine chromium and fructose for weight control and use thereof | 1996 | ALLEN; ANN DE WEES T. | 72 |
Where research is gaining momentum
Research themes ranked by publication activity show where scientific interest is accelerating around this compound.
| # | Research topic | Papers |
|---|---|---|
| 1 | Coffee research and impacts | 112 |
| 2 | Ion channel regulation and function | 64 |
| 3 | Neuroscience and Neuropharmacology Research | 31 |
| 4 | Adenosine and Purinergic Signaling | 27 |
| 5 | Migraine and Headache Studies | 24 |
| 6 | Cardiac electrophysiology and arrhythmias | 22 |
| 7 | Pharmacogenetics and Drug Metabolism | 19 |
| 8 | Muscle metabolism and nutrition | 18 |
| 9 | Advancements in Transdermal Drug Delivery | 17 |
| 10 | Analytical Chemistry and Chromatography | 15 |
Technology trend analysis
Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.
See Cypris in actionWho's driving the science
The most-published authors working with this compound, alongside their primary affiliations.
| # | Author | Affiliation | Papers |
|---|---|---|---|
| 1 | Juan Del Coso | Universidad Rey Juan Carlos | 61 |
| 2 | Bertil B. Fredholm | Karolinska Institutet | 50 |
| 3 | David Eisner | University of Liverpool | 26 |
| 4 | Christa E. Müller | University of Bonn | 25 |
| 5 | Donald M. Bers | Loyola University Chicago | 25 |
| 6 | Humbert De Smedt | KU Leuven | 12 |
| 7 | Andrew Smith | Cardiff University | 20 |
| 8 | Hui Wang | Wuhan University | 19 |
| 9 | Hiroyuki Tsuchiya | Kanazawa University | 16 |
| 10 | Jiang‐Fan Chen | Boston University | 15 |
Research leaders
This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.
See Cypris in actionThe literature that defines it
The most-cited papers anchoring the scientific record for this compound.
| Title | Year | Cited by | Topic |
|---|---|---|---|
| Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration | 2007 | 8515 | Meta-analysis and systematic reviews |
| Participation of p53 protein in the cellular response to DNA damage. | 1991 | 3801 | Cancer-related Molecular Pathways |
| Risk Factors for Hip Fracture in White Women | 1995 | 3590 | Bone health and osteoporosis research |
| Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use | 1999 | 2621 | Neuroscience and Neuropharmacology Research |
| Social Jetlag: Misalignment of Biological and Social Time | 2006 | 2606 | Sleep and related disorders |
Frequently asked questions
Common questions about this compound's patent and research landscape, answered from the underlying data.
What is the molecular formula and structure of caffeine?
Which organizations hold the most patents related to caffeine?
What are the leading research topics associated with caffeine studies?
Who are the most prolific authors publishing research on caffeine?
What patent classification codes are most common for caffeine-related patents?