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Repinotan hydrochloride

2-[4-[[(2R)-3,4-dihydro-2H-chromen-2-yl]methylamino]butyl]-1,1-dioxo-1,2-benzothiazol-3-one;hydrochloride · also: Branosyn, Bay-x-3702, Bay x 3702, Repinotan HCl, RepinotanHydrochloride, Repinotan (hydrochloride)

FormulaC21H25ClN2O4S
Mol. weight436.951
PubChem CID198756
InChIKeyIGKYREHZJIHPML-UNTBIKODSA-N
SMILESC1CC2=CC=CC=C2O[C@H]1CNCCCCN3C(=O)C4=CC=CC=C4S3(=O)=O.Cl
125Patents
36Research papers
2Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Ascendis Pharma AS23
2Bayer AG22
3H Lundbeck AS20
4Alcon Inc15
5Otsuka Pharmaceutical Co Ltd9
6Ono Pharmaceutical Co Ltd4
7Novartis AG2
8GlaxoSmithKline Intellectual Property No 2 Ltd1

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations103
2A61PTherapeutic activity (drug indications)102
3C07DHeterocyclic compounds57
4Y02PClimate change mitigation: production24
5Y10TCross-reference (technical subjects)23
6G01NInvestigating / analysing materials17
7C08JWorking-up of plastics7
8C07KPeptides6
9A61MDevices for introducing media into the body1
10C12QMeasuring/testing involving enzymes1

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Francesc ArtigasInstitut d'Investigacions Biomèdiques de Barcelona6
2Josef KrieglsteinPhilipps University of Marburg5
3Christine SchaperPhilipps University of Marburg4
4Frank MaulerBayer (Germany)4
5Georg WensingBayer (Germany)3
6Irina SemkovaPhilipps University of Marburg3
7Lorenzo Díaz-MataixInstitut d'Investigacions Biomèdiques de Barcelona3
8Michael BöettcherBayer (Germany)3
9Pau CeladaConsorci Institut D'Investigacions Biomediques August Pi I Sunyer3
10Albert AdellInstitut d'Investigacions Biomèdiques de Barcelona2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Repinotan hydrochloride?

Repinotan hydrochloride has the molecular formula C21H25ClN2O4S and a molecular weight of 436.951 g/mol.

Which organizations hold the most patents for Repinotan hydrochloride?

The leading patent holders are Ascendis Pharma AS with 23 patents, Bayer AG with 22 patents, and H Lundbeck AS with 20 patents.

What are the main research focuses in published papers on this compound?

Key research topics include the compound's role as a selective 5-HT1A receptor agonist, with studies examining postsynaptic receptor influence on behavior, neuroprotection in traumatic brain injury, G protein-coupled receptor signaling through MAPK pathways, and potential benefits in Parkinson's disease models.

Who are the most prolific authors publishing on Repinotan hydrochloride research?

The leading authors are Francesc Artigas from Institut d'Investigacions Biomèdiques de Barcelona with 6 papers, Josef Krieglstein from Philipps University of Marburg with 5 papers, and Christine Schaper also from Philipps University of Marburg with 4 papers.

What is the distribution of patent filings across intellectual property classifications?

The majority of patents fall under pharmaceutical and chemical classifications: A61K (pharmaceutical preparations) with 103 patents, A61P (therapeutic applications) with 102 patents, and C07D (heterocyclic compounds) with 57 patents. Additional coverage includes Y02P (environmental technology), Y10T (technical subjects), and G01N (analytical methods).

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