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Brahol

(1R,2S,4S,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol · also: Pinitol, D-Pinitol, Quebrachit, Pinitol TMS, Quebrachitol, L-Quebrachitol

FormulaC7H14O6
Mol. weight194.183
PubChem CID151108
InChIKeyDSCFFEYYQKSRSV-MBXCVVGISA-N
SMILESCOC1[C@@H]([C@H](C([C@@H]([C@H]1O)O)O)O)O
874Patents
27Research papers
159Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Nektar Therapeutics202
2Boston Scientific Scimed Inc69
3Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung eV41
4Yokohama Rubber Co Ltd26
5Nektar Therapeutics AL Corp24
6Fujifilm Corp18
7Goodrich Corp16
8Deutsches Krebsforschungszentrum DKFZ11
9Rutgers, The State University of New Jersey11
10Bridgestone Corp10

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations449
2A61PTherapeutic activity (drug indications)311
3C08LPolymer compositions (blends)224
4C08GPolymers from non-vinyl bonds (e.g. polyamides, polyesters)220
5C07CAcyclic and carbocyclic compounds146
6C07DHeterocyclic compounds84
7C07KPeptides74
8C08KPolymer compositions (additives)70
9A61LSterilising / disinfecting materials65
10C08JWorking-up of plastics61

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
A kind of quebrachite extraction process2019Si Ailing2
A kind of Chromatographic purification method of quebrachite2019Hainan Zhongoak Technology Co., Ltd.1
A kind of absorption type quebrachite extraction process2019Si Ailing0
A kind of store method of quebrachite2019Hainan Zhongoak Technology Co., Ltd.0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Carbohydrate Chemistry and Synthesis1
2Plant nutrient uptake and metabolism1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Telma L. G. LemosUniversidade Federal do Ceará3
2Emily C. MoodyUniversity of Minnesota1
3Huicong WangSouth China Agricultural University2
4Jianguo LiSouth China Agricultural University2
5K. R. VijayakumarAnnamalai University2
6Luciana Lucas MachadoUniversidade Federal do Ceará2
7V. S. N. RaoUniversidade Federal do Ceará2
8Xu‐Ming HuangSouth China Agricultural University2
9Zichen WuSouth China Agricultural University2
10A. Berenice Aguilar‐GuadarramaUniversidad Autónoma del Estado de Morelos1

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Brahol?

Brahol, also known as Pinitol or Quebrachitol, has the molecular formula C7H14O6 and a molecular weight of 194.183 g/mol. Its IUPAC name is (1R,2S,4S,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol.

Which organizations hold the most patents related to Brahol?

Nektar Therapeutics leads with 202 patents related to Brahol, followed by Boston Scientific Scimed Inc with 69 patents and Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV with 41 patents.

What research topics are associated with Brahol publications?

Published research on Brahol covers topics including Carbohydrate Chemistry and Synthesis, Wnt/β-catenin signaling in development and cancer, Phytochemicals and Antioxidant Activities, and Antimicrobial Resistance in Staphylococcus.

What are some key biological activities demonstrated by Brahol in recent studies?

Recent studies show that l-Quebrachitol promotes the proliferation, differentiation, and mineralization of MC3T3-E1 cells through the BMP-2/Runx2/MAPK/Wnt/β-catenin signaling pathway, and Quebrachitol inhibits biofilm formation and virulence production against methicillin-resistant Staphylococcus aureus.

How has patent activity for Brahol evolved in recent years?

Patent activity for Brahol has shown significant growth, with 52 patents filed in 2022 and 67 in 2024. The last three years (2022–2024) account for 170 of the 874 total patents, representing increased research and development interest in this compound.

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