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L-Quebrachitol

(1R,2S,4S,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol · also: Brahol · Quebrachit · Quebrachitol · (-)-Quebrachitol · L-(-)-2-O-Methylinositol · 2-O-Methyl-chiro-inositol

FormulaC7H14O6
Mol. weight194.183
PubChem CID151108
InChIKeyDSCFFEYYQKSRSV-MBXCVVGISA-N
SMILESCOC1[C@@H]([C@H](C([C@@H]([C@H]1O)O)O)O)O
874Patents
27Research papers
148Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Nektar Therapeutics226
2Boston Scientific Corp69
3Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung eV41
4Yokohama Rubber Co Ltd26
5Fujifilm Holdings Corp18
6RTX Corp16
7German Cancer Research Center11
8Rutgers, The State University of New Jersey11
9Bridgestone Corp10
10Cornell University10

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations449
2A61PTherapeutic activity (drug indications)311
3C08LPolymer compositions (blends)224
4C08GPolymers from non-vinyl bonds (e.g. polyamides, polyesters)220
5C07CAcyclic and carbocyclic compounds146
6C07DHeterocyclic compounds84
7C07KPeptides74
8C08KPolymer compositions (additives)70
9A61LSterilising / disinfecting materials65
10C08JWorking-up of plastics61

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Method for extracting quebrachitol from sapindaceae plant lychee and longan201113
Method for extracting quebrachitol from natural rubber whey201211
Method for recovering quebrachitol from rubber latex serum1930Lanxess AG9
Method for extracting quebrachitol from natural latex20127
L-QUEBRACHITOL COSMETIC1990Yokohama Rubber Co Ltd7

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20161
20171
20181
20191
20202
20221

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Telma L. G. LemosUniversidade Federal do Ceará3
2K. R. VijayakumarAnnamalai University2
3Zichen WuSouth China Agricultural University2
4Xu‐Ming HuangSouth China Agricultural University2
5Luciana Lucas MachadoUniversidade Federal do Ceará2
6V. S. N. RaoUniversidade Federal do Ceará2
7Huicong WangSouth China Agricultural University2
8Florian Roquet1
9Khozirah ShaariUniversiti Putra Malaysia1
10Jun FanEmory University1

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of L-Quebrachitol?

L-Quebrachitol has the molecular formula C7H14O6 and a molecular weight of 194.183 g/mol. Its canonical name is (1R,2S,4S,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol.

Which organizations hold the most patents related to L-Quebrachitol?

Nektar Therapeutics leads with 226 patents, followed by Boston Scientific Corp with 69 patents, and Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung eV with 41 patents related to L-Quebrachitol.

What patent classes dominate L-Quebrachitol patent filings?

Pharmaceutical and biomedical applications dominate, with CPC subclass A61K (medicines and medical preparations) accounting for 449 patents, followed by A61P (specific therapeutic activity of chemical compounds) with 311 patents. Polymer-related classes C08L and C08G account for 224 and 220 patents respectively.

What biological activities of L-Quebrachitol have been reported in recent scientific literature?

Recent papers report that L-quebrachitol promotes proliferation, differentiation, and mineralization of osteoblast cells via the BMP-2/Runx2/MAPK/Wnt/β-catenin signaling pathway, and inhibits biofilm formation and virulence production in methicillin-resistant Staphylococcus aureus. It has also been identified as a natural product occurring in plants such as Allophylus edulis and litchi.

What is the patent trend for L-Quebrachitol over the last decade?

Patent filings for L-Quebrachitol have grown significantly, with 21 patents in 2016 rising to 67 in 2024. The total patent portfolio includes 874 patents, with 148 filed in the last three years. Paper publications remain limited, with 27 papers identified and 0 papers in the last three years.

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