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2-Chloronicotinic acid

2-chloropyridine-3-carboxylic acid · also: chloronicotinic acid · 2-Chloronicotinicacid · 2-choronicotinic acid · 2chloronicotinic acid · 2-chloro nicotinic acid · 2-Chloro-nicotinic acid

FormulaC6H4ClNO2
Mol. weight157.553
PubChem CID76258
InChIKeyIBRSSZOHCGUTHI-UHFFFAOYSA-N
SMILESC1=CC(=C(N=C1)Cl)C(=O)O
3,964Patents
21Research papers
236Patents - last 3 years
1Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Pfizer Inc228
2Roche Holding AG175
3Amgen Inc87
4C.H. Boehringer Sohn AG and Co KG70
5Abbott Laboratories64
6Takeda Pharmaceutical Co Ltd61
7Merck and Co Inc60
8Eli Lilly and Co45
9AstraZeneca PLC40
10Astellas Pharma Inc36

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C07DHeterocyclic compounds3,258
2A61PTherapeutic activity (drug indications)2,548
3A61KMedicinal preparations1,264
4C07CAcyclic and carbocyclic compounds484
5A01NPreservation of bodies; biocides; pest repellents262
6Y02AClimate change adaptation158
7C07FOrganometallic compounds153
8C07BGeneral methods of organic chemistry109
9Y02PClimate change mitigation: production98
10C07KPeptides88

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Preparation method of 2-chloronicotinic acid2008Zhejiang Medicine Co Ltd23
PREPARATION OF 2-CHLORONICOTINIC ACID198410
Nitrilase mutant and application thereof in catalytic synthesis of 2-chloronicotinic acid2020Zhejiang University of Technology9
Process for the production of pure white 2-chloronicotinic acid1979Lonza Group AG8
Synthesis method of 2-chloronicotinic acid and derivative thereof2013Zhejiang University of Technology7

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20201
20221
20231

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Larry A. SklarUniversity of New Mexico3
2Matthew SaundersUniversity of New Mexico3
3Steven W. GravesLos Alamos National Laboratory3
4Muhammad Naeem KhanIslamia University of Bahawalpur3
5Muhammad Nadeem ArshadGovernment College University, Lahore3
6Islam Ullah KhanGovernment College University, Lahore3
7Misbahul Ain KhanIslamia University of Bahawalpur3
8Bruce S. EdwardsUniversity of New Mexico3
9Anton SimeonovNational Center for Advancing Translational Sciences2
10Muhammad Nawaz TahirUniversity of Sargodha2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and molecular weight of 2-chloronicotinic acid?

2-Chloronicotinic acid has the molecular formula C6H4ClNO2 and a molecular weight of 157.553 g/mol.

Which companies have filed the most patents related to 2-chloronicotinic acid?

The leading patent assignees for 2-chloronicotinic acid are Pfizer Inc with 228 patents, Roche Holding AG with 175 patents, and Amgen Inc with 87 patents.

What are the key patent application areas for 2-chloronicotinic acid based on CPC classification?

The primary patent application areas are heterocyclic compound chemistry (C07D with 3258 patents), pharmaceutical preparations and medical uses (A61P with 2548 patents), and medicinal compounds (A61K with 1264 patents).

What was the trend in patent filings for 2-chloronicotinic acid over recent years?

Patent filings peaked in 2022 with 151 patents, followed by 2023 with 119 patents and 2024 with 115 patents. In the last 3 years (2022-2024), a total of 236 patents were filed.

Are there known synthesis methods for 2-chloronicotinic acid documented in patent literature?

Yes, multiple synthesis methods are patented. Notable examples include a preparation method by Zhejiang Medicine Co Ltd, a nitrilase mutant application for catalytic synthesis by Zhejiang University of Technology, and a process for producing pure white 2-chloronicotinic acid by Lonza Group AG from 1979.

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