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Bixin

(2E,4E,6E,8E,10E,12E,14E,16Z,18E)-20-methoxy-4,8,13,17-tetramethyl-20-oxoicosa-2,4,6,8,10,12,14,16,18-nonaenoic acid · also: a-Bixin · Isobixin · cis-Bixin · alpha-Bixin · Stable bixin · Annatto (E 160b)

FormulaC25H30O4
Mol. weight394.511
PubChem CID5281226
InChIKeyRAFGELQLHMBRHD-SLEZCNMESA-N
SMILESC/C(=C\C=C\C=C(/C)\C=C\C=C(\C)/C=C/C(=O)OC)/C=C/C=C(\C)/C=C/C(=O)O
4,033Patents
120Research papers
243Patents - last 3 years
13Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Mondelez International Inc347
2BASF SE294
3Mars Inc110
4DSM Firmenich AG93
5Fujifilm Holdings Corp86
6Nissan Chemical Corp61
7Nippon Fine Chemical Co Ltd59
8Colgate Palmolive Co51
9Maxingvest AG48
10Amyris Inc47

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations1,803
2A23LFoods and beverages (general)1,098
3A61QCosmetics, personal care980
4A61PTherapeutic activity (drug indications)939
5A23VFoods, foodstuffs - indexing scheme704
6A23GCocoa, chocolate, confectionery598
7A23KAnimal feeds446
8A23P336
9C09B221
10C07CAcyclic and carbocyclic compounds202

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Bixin colorant compositions2000Icahn Enterprises LP37
BIXIN DERIVATIVE AND CYTOPROTECTIVE AGENT20126
Carotenoid dye esp. lycopene prepn. - by esterifying bixin, reducing ester and reacting alcohol with ketone esp. methyl heptenone19776
Process to convert bixin to a food color and the resulting product19574
Novel esters of bixins and norbixins and process for the manufacture thereof1956Roche Holding AG3

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20166
20177
20188
20199
20206
20217
20226
20236
20245
20252

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Siva RamamoorthyVellore Institute of Technology University7
2Shasha TaoSoochow University6
3C. George Priya DossVellore Institute of Technology University5
4Lusânia Maria Greggi AntunesUniversidade de São Paulo5
5Alessandro de Oliveira RiosUniversidade Federal do Rio Grande do Sul5
6Renata Rivera‐MadridSecretaría de Investigación, Innovación y Educación Superior4
7Teruo KawadaKyoto University3
8Nobuyuki TakahashiKyoto University3
9Wagner Campos OtoniUniversidade Federal de Viçosa3
10Tatiana EmanuelliUniversidade Federal de Santa Maria3

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and structure of bixin?

Bixin has the molecular formula C25H30O4 with a molecular weight of 394.511. Its canonical IUPAC name is (2E,4E,6E,8E,10E,12E,14E,16Z,18E)-20-methoxy-4,8,13,17-tetramethyl-20-oxoicosa-2,4,6,8,10,12,14,16,18-nonaenoic acid. It is also known as annatto (E 160b) and contains a characteristic 9-cis double bond configuration.

Which companies hold the most patents related to bixin?

The leading patent assignees for bixin are Mondelez International Inc with 347 patents, BASF SE with 294 patents, and Mars Inc with 110 patents. Other significant patent holders include DSM Firmenich AG with 93 patents and Fujifilm Holdings Corp with 86 patents.

What are the major patent classification categories for bixin?

Bixin patents are primarily classified under A61K (medicinal preparations) with 1803 patents, followed by A23L (food technology) with 1098 patents and A61Q (specific active therapeutic agents) with 980 patents. Additional significant classifications include A61P (pharmaceutical preparations) with 939 patents and A23V (edible oils and fats) with 704 patents.

What research topics are covered in major bixin papers?

Key research areas include the biosynthesis of bixin as a food and cosmetic pigment, its interaction with cyclodextrins and protein systems in food applications, and its antioxidant and cytoprotective properties. Notable papers address photosynthetic processes and mechanisms, curcumin interactions, oxidative stress and genomics, and proteins in food systems.

Who are the most prolific academic authors publishing on bixin?

Leading authors include Siva Ramamoorthy from Vellore Institute of Technology University with 7 papers, Shasha Tao from Soochow University with 6 papers, and C. George Priya Doss also from Vellore Institute of Technology University with 5 papers. Other active researchers include Lusânia Maria Greggi Antunes from Universidade de São Paulo and Alessandro de Oliveira Rios from Universidade Federal do Rio Grande do Sul, each with 5 papers.

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