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Berenil

2-acetamidoacetic acid;4-[2-(4-carbamimidoylphenyl)iminohydrazinyl]benzenecarboximidamide · also: Azidin · Azidine · Ganaseg · Beronal · Bevenil · Ganasag

FormulaC18H22N8O3
Mol. weight398.427
PubChem CID65060
InChIKeyXJLITJHUQRBWPN-UHFFFAOYSA-N
SMILESCC(=O)NCC(=O)O.C1=CC(=CC=C1C(=N)N)NN=NC2=CC=C(C=C2)C(=N)N
1,145Patents
591Research papers593 indexed in detail
99Patents - last 3 years
22Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Bruker Corp58
2Thermo Fisher Scientific Inc54
3Gilead Sciences Inc46
4Cerus Corp36
5Boston Scientific Corp34
6Pfizer Inc27
7LGC Science Corp SARL18
8GSK PLC13
9New York University12
10State University System of Florida11

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations483
2A61PTherapeutic activity (drug indications)471
3C07DHeterocyclic compounds318
4C12QMeasuring/testing involving enzymes287
5C12NMicroorganisms, enzymes139
6Y02AClimate change adaptation120
7C07HSugars and derivatives108
8G01NInvestigating / analysing materials98
9C07KPeptides77
10C07CAcyclic and carbocyclic compounds71

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Oligonucleotide conjugates19951,032
Covalently linked oligonucleotide minor grove binder conjugates1998Bruker Corp332
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders2001Bruker Corp193
Covalently linked oligonucleotide minor grove binder conjugates2000161
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders2002134

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
201619
201717
201816
201918
202026
20219
202214
20239
20249
20254

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Ikuo IgarashiObihiro University of Agriculture and Veterinary Medicine13
2Mohamed Abdo RizkObihiro University of Agriculture and Veterinary Medicine11
3Stephen NeidleInstitute of Cancer Research10
4Mohammed MammanInternational Centre of Insect Physiology and Ecology6
5Harry P. de KoningUniversity of Glasgow5
6Harrison ChitamboOsaka Prefecture University5
7Getachew TerefeAddis Ababa University5
8Andrew S. PeregrineInternational Centre of Insect Physiology and Ecology5
9S.K. MolooInternational Centre of Insect Physiology and Ecology5
10Shiby KuriakoseUniversity of Manitoba4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition and weight of Berenil?

Berenil has the molecular formula C18H22N8O3 with a molecular weight of 398.427. It is also known by several synonyms including Diminazene Aceturate, Azidin, and Azidine.

Which organizations hold the most patents related to Berenil?

Bruker Corp holds the most patents with 58, followed by Thermo Fisher Scientific Inc with 54 patents, and Gilead Sciences Inc with 46 patents related to Berenil.

What are the main research topics associated with Berenil publications?

Publications on Berenil cover several key topics including Trypanosoma species research and implications, with notable papers on trypanosomiasis outbreaks and pharmacology of diminazene. Research also includes Pulmonary Hypertension Research and Treatments, Nanoparticle-Based Drug Delivery, and Lipid Membrane Structure and Behavior.

Who are the leading authors publishing research on Berenil?

Ikuo Igarashi from Obihiro University of Agriculture and Veterinary Medicine leads with 13 papers, followed by Mohamed Abdo Rizk also from Obihiro University of Agriculture and Veterinary Medicine with 11 papers, and Stephen Neidle from Institute of Cancer Research with 10 papers.

How has patent activity for Berenil changed over recent years?

Patent filings show fluctuation with 55 patents in 2022, 53 in 2023, and 42 in 2024. The last three years (2022-2024) averaged 50 patents per year. Paper publications have been more variable, with 14 papers in 2022, 9 papers in 2023, and 9 papers in 2024, for a three-year average of 11.7 papers annually.

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