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Berenil

2-acetamidoacetic acid;4-[2-(4-carbamimidoylphenyl)iminohydrazinyl]benzenecarboximidamide · also: Azidin, Azidine, Ganaseg, Beronal, Bevenil, Ganasag

FormulaC18H22N8O3
Mol. weight398.427
PubChem CID65060
InChIKeyXJLITJHUQRBWPN-UHFFFAOYSA-N
SMILESCC(=O)NCC(=O)O.C1=CC(=CC=C1C(=N)N)NN=NC2=CC=C(C=C2)C(=N)N
1,145Patents
591Research papers
102Patents - last 3 years
22Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Gilead Sciences Inc46
2Life Technologies Corp40
3Cerus Corp36
4BTG International Ltd31
5Epoch Biosciences Inc28
6Anacor Pharmaceuticals LLC19
7Biosearch Technologies Inc18
8Applied Biosystems Inc13
9ELITechGroup MDx LLC13
10Genelabs Technologies Inc13

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations483
2A61PTherapeutic activity (drug indications)471
3C07DHeterocyclic compounds318
4C12QMeasuring/testing involving enzymes287
5C12NMicroorganisms, enzymes139
6Y02AClimate change adaptation120
7C07HSugars and derivatives108
8G01NInvestigating / analysing materials98
9C07KPeptides77
10C07CAcyclic and carbocyclic compounds71

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Trypanosoma species research and implications6
2DNA and Nucleic Acid Chemistry3
3Renin-Angiotensin System Studies2
4Vector-borne infectious diseases2
5Agriculture and Rural Development Research1
6Bacteriophages and microbial interactions1
7Glaucoma and retinal disorders1
8Microbial metabolism and enzyme function1
9Pharmacological Effects and Assays1
10Pulmonary Hypertension Research and Treatments1

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1F. W. JenningsUniversity of Glasgow12
2Anderson J. FerreiraUniversidade Federal de Minas Gerais11
3Aleksandro S. Da SilvaUniversidade do Estado de Santa Catarina9
4Anil Bhanudas GaikwadBirla Institute of Technology and Science, Pilani6
5Erich ZweygarthFreie Universität Berlin6
6Ikuo IgarashiObihiro University of Agriculture and Veterinary Medicine6
7A. S. PeregrineInternational Centre of Insect Physiology and Ecology5
8Akira ArakawaOsaka Prefecture University5
9Andrew S. PeregrineInternational Centre of Insect Physiology and Ecology5
10Burkhard BauerFreie Universität Berlin5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Berenil?

Berenil has the molecular formula C18H22N8O3 and a molecular weight of 398.427. Its canonical chemical name is 2-acetamidoacetic acid;4-[2-(4-carbamimidoylphenyl)iminohydrazinyl]benzenecarboximidamide, with an InChI Key of XJLITJHUQRBWPN-UHFFFAOYSA-N.

What are the primary research topics associated with Berenil in the scientific literature?

The primary research topic is Trypanosoma species research and implications, which accounts for 6 papers. Other topics include DNA and Nucleic Acid Chemistry (3 papers), Renin-Angiotensin System Studies (2 papers), and Vector-borne infectious diseases (2 papers).

Which organizations hold the most patents related to Berenil?

Gilead Sciences Inc leads with 46 patents, followed by Life Technologies Corp with 40 patents, and Cerus Corp with 36 patents. BTG International Ltd holds 31 patents, and Epoch Biosciences Inc holds 28 patents.

What notable research papers have been published about Berenil's properties and applications?

A 1993 paper titled "Pharmacology of diminazene: a review" has 192 citations. A 2002 paper on "Lipid-Drug-Conjugate (LDC) Nanoparticles as Novel Carrier System for the Hydrophilic Antitrypanosomal Drug Diminazenediaceturate" has 173 citations. A 2013 paper titled "Diminazene Attenuates Pulmonary Hypertension and Improves Angiogenic Progenitor Cell Functions in Experimental Models" has 175 citations.

What patent classification categories dominate the Berenil patent landscape?

The leading CPC classification is A61K (covering pharmaceutical preparations) with 483 patents, followed by A61P (specific therapeutic activity of chemical compounds) with 471 patents. C07D (heterocyclic compounds) accounts for 318 patents, and C12Q (measuring or testing processes involving enzymes or microorganisms) covers 287 patents.

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