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Azure A

(7-aminophenothiazin-3-ylidene)-dimethylazanium chloride · also: Azur A, Azuresin, Sinitest, Diagnex Blue, giemsa-stain, Giemsa stain

FormulaC14H14ClN3S
Mol. weight291.797
PubChem CID13735
InChIKeyNALREUIWICQLPS-UHFFFAOYSA-N
SMILESC[N+](=C1C=CC2=NC3=C(C=C(C=C3)N)SC2=C1)C.[Cl-]
6,965Patents
119Research papers
922Patents - last 3 years
6Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
110X Genomics Inc155
2LG Chem Ltd90
3Covestro Deutschland AG75
4Kimberly Clark Worldwide Inc69
5SmithKline Beecham Corp52
6F Hoffmann La Roche AG51
7Labrador Diagnostics LLC48
8Arkray Inc46
9Massachusetts Institute of Technology46
10Procter and Gamble Co41

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations2,929
2A61PTherapeutic activity (drug indications)2,736
3G01NInvestigating / analysing materials1,813
4C12NMicroorganisms, enzymes1,081
5C07KPeptides1,056
6C12QMeasuring/testing involving enzymes873
7C07DHeterocyclic compounds614
8Y02AClimate change adaptation612
9A61LSterilising / disinfecting materials462
10Y10SCross-reference (legacy)252

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
GRAPHIC DIAGNOSIS PROBE FOR DISEASE ACCEPTING ACCUMULATING AMYLOID BY AZURE A ANALOG COMPOUND AND COMPOSITION FOR GRAPHIC DIAGNOSIS CONTAINING THE SAME2000BF KENKYUSHO:KK14
A kind of method of quick carry out Rui Shi Giemsa stainings2018SUZHOU FENGTAI MEDICAL SUPPLIES TRADING CO., LTD.8
Method for purifying electronic mediator azure C2022Genclonn Biotech (Hangzhou) Co.,Ltd.1
Method for detecting quality of Rui-Giemsa staining solution and method for improving quality of Rui-Giemsa staining solution2023HENAN CELNOVTEBIO BIOTECHNOLOGY. Inc.0
Method for purifying electronic mediator azure C2022Genclonn Biotech (Hangzhou) Co.,Ltd.0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Electrochemical sensors and biosensors1
2Food Quality and Safety Studies1
3Quinazolinone synthesis and applications1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Guangwen CaoNanjing University4
2Qingcai Jiao4
3Victor C. YangUniversity of Michigan4
4Encarnación LorenzoUniversidad Autónoma de Madrid3
5F. ParienteUniversidad Autónoma de Madrid3
6Gopinatha Suresh KumarIndian Institute of Chemical Biology3
7Robert A. DrongowskiUniversity of Michigan3
8Tania García‐MendiolaUniversidad Autónoma de Madrid3
9C. Gómez-AnquelaUniversidad Autónoma de Madrid2
10C.-L. C. TengUniversity of Michigan2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition of Azure A?

Azure A has the molecular formula C14H14ClN3S with a molecular weight of 291.797. Its canonical name is (7-aminophenothiazin-3-ylidene)-dimethylazanium chloride, and it is also known by many synonyms including Azuresin, Diagnex Blue, and N,N-Dimethylthionine.

Which organizations hold the most patents related to Azure A?

10X Genomics Inc holds the most patents with 155, followed by LG Chem Ltd with 90 patents and Covestro Deutschland AG with 75 patents. Other significant patent holders include Kimberly Clark Worldwide Inc with 69 patents and SmithKline Beecham Corp with 52 patents.

How many patents and papers have been filed or published on Azure A in recent years?

The compound has substantial coverage with 6,965 total patents and 119 papers in the database. In the last three years, there were 922 new patents and 6 new papers, demonstrating continued research interest. Patent filings peaked in 2024 with 403 patents, while 2025 shows 301 patents to date.

What are the main research topics associated with Azure A?

Research on Azure A spans multiple domains, with the top patent classification being A61K (pharmaceutical preparations) with 2,929 patents, followed by A61P (medicinal preparations) with 2,736 patents and G01N (investigating or analyzing materials) with 1,813 patents. Key research topics include electrochemical sensors and biosensors, food quality and safety studies, and quinazolinone synthesis and applications.

What notable scientific publications reference Azure A and related compounds?

Published research includes work on photocatalytic degradation of Azure dyes using nano TiO2 with 138 citations, a metachromatic dye method for identifying skeletal muscle fiber types with 116 citations, and potentiation of photoinactivation of bacteria using phenothiazinium dyes with 85 citations. These papers span applications from materials science to microbiology and medical diagnostics.

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