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Azosulfime

1,2,4-thiadiazole

FormulaC2H2N2S
Mol. weight86.112
PubChem CID6451464
InChIKeyYGTAZGSLCXNBQL-UHFFFAOYSA-N
SMILESC1=NSC=N1
50,189Patents
22Research papers
3,549Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Merck Patent GmbH3,916
2BASF SE2,635
3Takeda Pharmaceutical Co Ltd2,038
4Merck Sharp and Dohme LLC1,967
5Bristol Myers Squibb Co1,616
6Bayer CropScience AG1,020
7Fujifilm Holdings Corp788
8Incyte Corp748
9AstraZeneca AB729
10Organon Pharma UK Ltd525

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C07DHeterocyclic compounds34,973
2A61PTherapeutic activity (drug indications)27,627
3A61KMedicinal preparations18,136
4C07CAcyclic and carbocyclic compounds6,371
5A01NPreservation of bodies; biocides; pest repellents5,723
6C09KMaterials for misc. applications5,566
7H10KOrganic semiconductors / OLEDs4,826
8C07FOrganometallic compounds4,705
9Y02EClimate change mitigation: energy4,183
10Y02PClimate change mitigation: production1,800

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Aihua WangJohnson & Johnson (United States)2
2Alan C. GibbsJohnson & Johnson (United States)2
3Ellen Sieber-McMasterJohnson & Johnson (United States)2
4Gee‐Hong KuoJohnson & Johnson (United States)2
5HU Zhi-yongJohnson & Johnson (United States)2
6Hamish RossJohnson & Johnson (United States)2
7Jolanta WodzinskaApotex (Canada)2
8Keith T. DemarestJohnson & Johnson (United States)2
9Lan ShenJohnson & Johnson (United States)2
10Lubing ZhouJohnson & Johnson (United States)2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Azosulfime?

Azosulfime has the molecular formula C2H2N2S with a molecular weight of 86.112. It is also known by its canonical name 1,2,4-thiadiazole and has the InChI Key YGTAZGSLCXNBQL-UHFFFAOYSA-N.

Which organizations hold the most patents related to Azosulfime?

The leading patent assignees in this field are Merck Patent GmbH with 3916 patents, BASF SE with 2635 patents, and Takeda Pharmaceutical Co Ltd with 2038 patents. Other major holders include Merck Sharp and Dohme LLC, Bristol Myers Squibb Co, and Bayer CropScience AG.

What research topics are associated with Azosulfime in the patent literature?

Patent classification codes show that Azosulfime research is predominantly concentrated in heterocyclic organic compounds (C07D with 34,973 patents), pharmaceutical preparations and therapies (A61P with 27,627 patents), and medicinal chemistry (A61K with 18,136 patents). Agricultural applications (A01N) also represent a significant area with 5,723 patents.

What are the main research applications documented in academic literature?

Academic papers document several applications of 1,2,4-thiadiazole compounds. These include use as a cathepsin B inhibitor, synthesis as irreversible inhibitors of transglutaminase, and investigation in thrombopoietin receptor agonists for platelet disorder treatments. Additional research covers electrochemical sensors and structural analysis of organo-sulfur-nitrogen rings.

How has patent activity in this field changed in recent years?

Patent filings related to Azosulfime have remained relatively consistent, with annual patent counts ranging from approximately 2,171 to 2,435 patents between 2016 and 2023. In the last three years, there were 3,549 total patents filed. However, 2024 and 2025 show a significant decline to 1,728 and 501 patents respectively, likely reflecting incomplete data for those years.

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