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1,2,4-Thiadiazole

1,2,4-thiadiazole

FormulaC2H2N2S
Mol. weight86.112
PubChem CID6451464
InChIKeyYGTAZGSLCXNBQL-UHFFFAOYSA-N
SMILESC1=NSC=N1
50,189Patents
22Research papers
3,278Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Merck Patent GmbH3,916
2BASF SE2,635
3Takeda Pharmaceutical Co Ltd2,038
4Merck Sharp & Dohme LLC1,967
5Bristol Myers Squibb Co1,616
6Bayer CropScience AG1,018
7Fujifilm Holdings Corp785
8Incyte Corp748
9Astellas Pharma Inc737
10AstraZeneca AB729

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C07DHeterocyclic compounds34,979
2A61PTherapeutic activity (drug indications)27,631
3A61KMedicinal preparations18,145
4C07CAcyclic and carbocyclic compounds6,371
5A01NPreservation of bodies; biocides; pest repellents5,723
6C09KMaterials for misc. applications5,568
7H10KOrganic semiconductors / OLEDs4,827
8C07FOrganometallic compounds4,710
9Y02EClimate change mitigation: energy4,185
10Y02PClimate change mitigation: production1,800

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Polymer of 1,2,4-thiadiazole and lubricants containing it as an additive1978Arkema Inc69
Novel disulfides derived from 1,2,4-thiadiazole1975Lubrizol Corp54
1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF2007BARBEY, SABINE44
3,5-Di-tertiary-butyl-4-hydroxyphenyl-1,3,4-thiadiazoles, and oxadiazoles and 3,5-di-tertiary-butyl-4-hydroxiphenyl- 1,2,4-thiadiazoles, -oxadiazoles as antiinflammatory agents1990Warner Lambert Co LLC33
1,2,4-oxadiazole and 1,2,4-thiadiazole derivatives of fenamates as antiinflammatory agents1992Warner Lambert Co LLC31

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Peroxisome Proliferator-Activated Receptors1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Aihua WangJohnson & Johnson (United States)2
2Alan C. GibbsJohnson & Johnson (United States)2
3Ana CastroInstituto de Química Médica2
4Arantxa EncinasInstituto de Química Médica2
5Carmen GilInstituto de Química Médica2
6Ellen Sieber-McMasterJohnson & Johnson (United States)2
7Gee‐Hong KuoJohnson & Johnson (United States)2
8HU Zhi-yongJohnson & Johnson (United States)2
9Hamish RossJohnson & Johnson (United States)2
10Jolanta WodzinskaApotex (Canada)2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of 1,2,4-thiadiazole?

1,2,4-thiadiazole has the molecular formula C2H2N2S with a molecular weight of 86.112 g/mol. Its InChI Key is YGTAZGSLCXNBQL-UHFFFAOYSA-N.

Which organizations hold the most patents related to 1,2,4-thiadiazole?

The leading patent assignees are Merck Patent GmbH with 3,916 patents, BASF SE with 2,635 patents, Takeda Pharmaceutical Co Ltd with 2,038 patents, Merck Sharp & Dohme LLC with 1,967 patents, and Bristol Myers Squibb Co with 1,616 patents.

What are the primary research areas for 1,2,4-thiadiazole based on patent classification?

The largest patent classification areas are organic chemistry compounds (C07D with 34,979 patents), pharmaceutical uses (A61P with 27,631 patents), and medicinal preparations (A61K with 18,145 patents).

What biological applications of 1,2,4-thiadiazole have been documented in literature?

Published research describes 1,2,4-thiadiazole applications including synthesis and therapeutic use, function as a cathepsin B inhibitor, use as an irreversible inhibitor of transglutaminase, and incorporation in thrombopoietin receptor agonists for platelet disorder treatment.

How has patent activity for 1,2,4-thiadiazole evolved recently?

Over the last three years, 3,278 patents related to 1,2,4-thiadiazole have been filed. Annual patent activity from 2020 to 2023 remained between 2,171 and 2,435 patents per year, with a decline to 1,728 in 2024.

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