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Arildone

4-[6-(2-chloro-4-methoxyphenoxy)hexyl]heptane-3,5-dione · also: Arildona · Arildonum · Arildone (USAN) · 4-(6-(2-Chloro-4-methoxyphenoxy)hexyl)-3,5-heptanedione · 4-(6-(2-Chloro-4-methoxy)phenoxy)hexyl-3,5-heptanedione

FormulaC20H29ClO4
Mol. weight368.898
PubChem CID41782
InChIKeyDIXRMZGIJNJUGL-UHFFFAOYSA-N
SMILESCCC(=O)C(CCCCCCOC1=C(C=C(C=C1)OC)Cl)C(=O)CC
1,293Patents
28Research papers
66Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Pfizer Inc107
2Mass General Brigham Inc52
3National Research Council of Science and Technology46
4The University of Texas System46
5Massachusetts Institute of Technology39
6Alnylam Pharmaceuticals Inc30
7Novartis AG28
8Aquestive Therapeutics Inc25
9Harvard University25
10Gilead Sciences Inc23

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations1,019
2A61PTherapeutic activity (drug indications)1,001
3Y02AClimate change adaptation341
4C12NMicroorganisms, enzymes333
5C07DHeterocyclic compounds315
6C07KPeptides186
7C07HSugars and derivatives103
8C07CAcyclic and carbocyclic compounds78
9A61MDevices for introducing media into the body49
10B82YNanotechnology42

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssignee
Analogs of arildone1994Merck and Co Inc
Analogs of arildone1992Merck and Co Inc

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Francis PancicSterling Research Group (United States)4
2Jerome EdelsonSterling Research Group (United States)3
3Lawrence A. CaliguiriAlbany Medical Center Hospital2
4John A. BossoUniversity of Utah2
5Ethel S. Zalay2
6James J. McSharryAlbany Medical Center Hospital2
7A.S. TymsSt. Mary’s Hospital2
8Albert BoeyéVrije Universiteit Brussel2
9R. VrijsenVrije Universiteit Brussel2
10David P. BenzigerSterling Research Group (United States)2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Arildone?

Arildone has the molecular formula C20H29ClO4 and a molecular weight of 368.898 g/mol. Its canonical chemical name is 4-[6-(2-chloro-4-methoxyphenoxy)hexyl]heptane-3,5-dione.

Which organizations hold the most patents related to Arildone?

Pfizer Inc leads with 107 patents, followed by Mass General Brigham Inc with 52 patents, National Research Council of Science and Technology with 46 patents, and The University of Texas System with 46 patents. Massachusetts Institute of Technology holds 39 patents related to Arildone.

What was the trend in Arildone patent filings over the past decade?

Patent filings peaked in 2016 with 63 patents and remained relatively consistent through the 2010s and early 2020s, ranging between 45 and 60 annually. However, filings dropped significantly in 2024 (25 patents) and 2025 (26 patents), with only 7 patents recorded in 2026.

What research topics are most associated with Arildone in published literature?

Published research on Arildone focuses primarily on antiviral applications. Key topics include virus-based gene therapy research, viral gastroenteritis research and epidemiology, respiratory viral infections research, HIV research and treatment, and RNA research and splicing. Notable studies examined arildone's antiviral activity against poliovirus and its effect on viral uncoating and modification.

Which CPC subclasses dominate the patent landscape for Arildone-related inventions?

The most frequently cited CPC subclasses are A61K (medicinal preparations) with 1019 patents and A61P (pharmaceutical preparations) with 1001 patents, indicating a strong focus on drug development. These are followed by Y02A (technologies for mitigation of or adaptation to climate change) with 341 patents and C12N (biotechnology) with 333 patents.

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