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Arbidol

ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate;hydrochloride · also: umifenovir, Arbidol HCl, Umifenovir HCl, Arbidolhydrochloride, Arbidol Hydrochloride, Umifenovir hydrochloride

FormulaC22H26BrClN2O3S
Mol. weight513.875
PubChem CID9958103
InChIKeyOMZHXQXQJGCSKN-UHFFFAOYSA-N
SMILESCCOC(=O)C1=C(N(C2=CC(=C(C(=C21)CN(C)C)O)Br)C)CSC3=CC=CC=C3.Cl
3,965Patents
233Research papers
895Patents - last 3 years
16Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Emory University224
2Gilead Sciences Inc92
3Arcus Biosciences Inc82
4Assembly Biosciences Inc64
5University of California San Diego UCSD63
6ModernaTx Inc61
7Vitaeris Inc59
8Personalis Inc43
9Vertex Pharmaceuticals Inc43
10Shanghai Institute of Materia Medica of CAS37

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations3,107
2A61PTherapeutic activity (drug indications)2,914
3C07KPeptides976
4Y02AClimate change adaptation883
5C12NMicroorganisms, enzymes757
6C07DHeterocyclic compounds737
7G01NInvestigating / analysing materials407
8C07HSugars and derivatives291
9C12QMeasuring/testing involving enzymes241
10C12YEnzyme nomenclature (EC numbers)172

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Intravenous administration preparation of arbidol and salt thereof and preparation method2006Hubei Huaheng Pharmaceutical Co.,Ltd.15
A kind of preparation method of arbidol HCl2016Shandong Luo Xin Pharmaceutical Group Plc13
Preparation method of arbidol hydrochloride2012HUBEI HUALONG BIOLOGICAL PHARMACEUTICAL CO., LTD.12
Preparation method and quality control method of arbidol hydrochloride tablet2011WANG CHANGRUI12
Arbidol dry suspension and preparation method thereof2011NORTHEAST PHARMACEUTICAL (SHENYANG) TECHNOLOGY DEVELOPMENT CO., LTD.11

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Influenza Virus Research Studies2
2Mosquito-borne diseases and control2

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Burtseva EiD.I. Ivanovsky Institute of Virology Russian Academy of Medical Sciences9
2Eve‐Isabelle PécheurUniversité Claude Bernard Lyon 19
3Irina A. LenevaResearch Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences9
4Stephen J. PolyakUniversity of Washington7
5E. P. SelkovaGabrichevsky Institute of Epidemiology and Microbiology5
6Hairong XiongWuhan University4
7Leneva IaFederal State University of Education4
8Shuster Am4
9A. N. SlepushkinMay Institute3
10Antonella PedutoUniversity of Salerno3

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Arbidol?

Arbidol has the molecular formula C22H26BrClN2O3S and a molecular weight of 513.875 g/mol. Its IUPAC name is ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate hydrochloride.

How many patents and papers cover Arbidol in the literature?

The Arbidol literature includes 3,965 patents in total, with 926 patents filed in the last 3 years. There are 233 papers identified through journal searches, with 16 papers published in the last 3 years.

Which institutions are leading patent holders for Arbidol-related research?

Emory University holds the most Arbidol-related patents with 224 patents, followed by Gilead Sciences Inc with 92 patents, Arcus Biosciences Inc with 82 patents, and Assembly Biosciences Inc with 64 patents. Shanghai Institute of Materia Medica of CAS is among the top assignees with 37 patents.

What are the most frequently cited research papers on Arbidol?

The most cited papers on Arbidol include studies on COVID-19 clinical applications: one comparing Arbidol combined with lopinavir/ritonavir versus lopinavir/ritonavir alone (526 citations), another on clinical characteristics of coronavirus patients receiving combined Chinese and Western medicine treatment (577 citations), and a paper on Arbidol monotherapy versus lopinavir/ritonavir for COVID-19 (435 citations). An earlier comprehensive review titled 'Arbidol as a broad-spectrum antiviral: An update' has 492 citations.

How has patent activity for Arbidol changed over recent years?

Patent filings for Arbidol have increased significantly, with 248 patents in 2020, rising to 473 in 2021, 467 in 2022, and reaching a peak of 590 in 2023. Paper publication activity surged in 2020 with 63 papers, then remained at lower levels through subsequent years.

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