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Arbidol

ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate;hydrochloride · also: Arbidol HCl · C22H26BrClN2O3S · Arbidol Hydrochloride · Arbidol (hydrochloride) · Umifenovir hydrochloride · Arbidol HCl (Umifenovir)

FormulaC22H26BrClN2O3S
Mol. weight513.875
PubChem CID9958103
InChIKeyOMZHXQXQJGCSKN-UHFFFAOYSA-N
SMILESCCOC(=O)C1=C(N(C2=CC(=C(C(=C21)CN(C)C)O)Br)C)CSC3=CC=CC=C3.Cl
3,965Patents
233Research papers231 indexed in detail
810Patents - last 3 years
16Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Emory University224
2Moderna Inc95
3Gilead Sciences Inc92
4Arcus Biosciences Inc82
5Assembly Biosciences Inc64
6University of California63
7CSL Ltd59
8H Lundbeck AS51
9Arbutus Biopharma Corp46
10Personalis Inc43

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations3,107
2A61PTherapeutic activity (drug indications)2,917
3C07KPeptides977
4Y02AClimate change adaptation884
5C12NMicroorganisms, enzymes757
6C07DHeterocyclic compounds737
7G01NInvestigating / analysing materials409
8C07HSugars and derivatives291
9C12QMeasuring/testing involving enzymes241
10C12YEnzyme nomenclature (EC numbers)172

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Intravenous administration preparation of arbidol and salt thereof and preparation method200615
A kind of preparation method of arbidol HCl201613
Preparation method of arbidol hydrochloride201212
Preparation method and quality control method of arbidol hydrochloride tablet201112
Arbidol dry suspension and preparation method thereof201111

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20167
20176
20185
20197
202063
202139
202210
20236
20249
20251

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Stephen J. PolyakUniversity of Washington10
2Burtseva EiD.I. Ivanovsky Institute of Virology Russian Academy of Medical Sciences9
3Eve‐Isabelle PécheurLyon 1 Université9
4Irina A. LenevaResearch Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences8
5Shuster Am5
6L'vov DkSechenov University4
7Leneva IaFederal State University of Education4
8С. В. БорисевичMinistry of Defence of the Russian Federation4
9Zifeng YangState Key Laboratory of Respiratory Disease4
10Shchelkanov MIuRussian Academy of Sciences4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Arbidol?

Arbidol has the molecular formula C22H26BrClN2O3S and a molecular weight of 513.875 g/mol. The compound is also known as Umifenovir hydrochloride.

How has patent activity around Arbidol changed in recent years?

Patent filings related to Arbidol have increased substantially, rising from 171 patents in 2016 to a peak of 590 in 2023. In the last three years, there were 810 total patents filed. The growth reflects increased research interest, particularly following 2020.

Which organizations are leading patent development for Arbidol?

Emory University leads with 224 patents, followed by Moderna Inc with 95 patents, Gilead Sciences Inc with 92 patents, and Arcus Biosciences Inc with 82 patents. Other significant contributors include Assembly Biosciences Inc, University of California, CSL Ltd, and H Lundbeck AS.

What are the primary research topics associated with Arbidol?

Research focuses on influenza virus and COVID-19 clinical applications. Key papers include work on the cytokine storm in severe influenza, clinical characteristics of COVID-19 pneumonia treated with combined therapies, comparative efficacy studies of Arbidol versus lopinavir/ritonavir, and reviews of Arbidol as a broad-spectrum antiviral agent.

Who are the most prolific authors publishing on Arbidol research?

Leading researchers include Stephen J. Polyak from University of Washington with 10 papers, Burtseva Ei from D.I. Ivanovsky Institute of Virology with 9 papers, and Eve‐Isabelle Pécheur from Lyon 1 Université with 9 papers. Other frequent contributors include Irina A. Leneva, Shuster Am, and researchers from Russian academic institutions.

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