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Medazepam

7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepine · also: Nobral · Elbrus · Benaon · Ansius · Resmit · Narsis

FormulaC16H15ClN2
Mol. weight270.76
PubChem CID4041
InChIKeyYLCXGBZIZBEVPZ-UHFFFAOYSA-N
SMILESCN1CCN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3
5,768Patents
172Research papers175 indexed in detail
280Patents - last 3 years
1Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Takeda Pharmaceutical Co Ltd328
2Grünenthal Pharma GmbH and Co KG182
3Teva Pharmaceutical Industries Ltd119
4Lonza Group AG102
5Roche Holding AG82
6Koch Inc75
7Acura Pharmaceuticals Inc56
8Nippon Shinyaku Co Ltd55
9Pfizer Inc48
10C.H. Boehringer Sohn AG and Co KG47

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations3,538
2A61PTherapeutic activity (drug indications)2,791
3C07DHeterocyclic compounds871
4C07KPeptides529
5C12NMicroorganisms, enzymes384
6G01NInvestigating / analysing materials358
7C07CAcyclic and carbocyclic compounds251
8Y02AClimate change adaptation230
9C08LPolymer compositions (blends)219
10A61J152

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
PINAVARIUM BROMURE AND MEDAZEPAM COMBINATION FOR IBS TREATMENT20171
A COMPRESSED SOLID ORAL DOSAGE FORM COMPRISING PINAVERIUM AND MEDAZEPAM20230
FILM COATED TABLET FORMULATIONS CONTAINING BUTYLSCOPOLAMINIUM BROMIDE AND MEDAZEPAM WITH IMPROVED DISSOLVING SPEED20220
MEDAZEPAM AND PROPANTHELINE COMPOSITION1973Roche Holding AG0
PHARMACEUTICAL COMPOSITIONS CONTAINING MEDAZEPAM AND AMITRIPTYLINE19700

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20192
20221
20231

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1S ManmaruTokyo Medical and Dental University5
2Т. А. ВоронинаSemenov Institute of Chemical Physics4
3N Boiadzhieva3
4Christian Stumpf3
5Petkov Vv3
6Sigismund Huck3
7K Náhunek3
8S. Yu. SelivankinaTimiryazev Institute of Plant Physiology2
9С. Б. СереденинSemenov Institute of Chemical Physics2
10G Gogolák2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical structure and molecular composition of Medazepam?

Medazepam has the canonical chemical name 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepine with the molecular formula C16H15ClN2 and a molecular weight of 270.76. Its InChI key is YLCXGBZIZBEVPZ-UHFFFAOYSA-N.

Which pharmaceutical companies have filed the most patents related to Medazepam?

The leading patent assignees for Medazepam-related inventions are Takeda Pharmaceutical Co Ltd with 328 patents, Grünenthal Pharma GmbH and Co KG with 182 patents, and Teva Pharmaceutical Industries Ltd with 119 patents.

What combination formulations involving Medazepam have been patented?

Patent filings document several combination formulations: Medazepam with pinavarium bromide for irritable bowel syndrome treatment, with pinaverium in a compressed solid oral dosage form, with butylscopolaminium bromide in film-coated tablets, with propantheline, and with amitriptyline in pharmaceutical compositions.

How does patent and publication activity for Medazepam vary over time?

Patent activity peaked in 2018 with 394 filings and has generally declined since, with 151 patents filed in 2024. Academic publication activity is minimal, with only 4 papers identified across the database spanning 2002 to 2023, with just 1 paper in the last 3 years.

What are the primary patent classification areas for Medazepam-related inventions?

Medazepam patents are predominantly classified under A61K (pharmaceutical preparations) with 3,538 patents, A61P (therapeutic applications) with 2,791 patents, and C07D (heterocyclic organic compounds) with 871 patents across the covered portfolio.

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