Book a demo

Chemical intelligence powered by cypris.ai

Medazepam

7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepine · also: Nobral, Elbrus, Benaon, Ansius, Resmit, Narsis

FormulaC16H15ClN2
Mol. weight270.76
PubChem CID4041
InChIKeyYLCXGBZIZBEVPZ-UHFFFAOYSA-N
SMILESCN1CCN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3
5,768Patents
172Research papers
299Patents - last 3 years
1Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Takeda Pharmaceutical Co Ltd241
2Grünenthal GmbH182
3Capsugel Belgium NV101
4Auspex Pharmaceuticals Inc82
5Millennium Pharmaceuticals Inc77
6F Hoffmann La Roche AG68
7Acura Pharmaceuticals Inc56
8Nippon Shinyaku Co Ltd51
9Johns Hopkins University40
10Boehringer Ingelheim Pharma GmbH and Co KG39

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

Visit Cypris

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations3,537
2A61PTherapeutic activity (drug indications)2,791
3C07DHeterocyclic compounds871
4C07KPeptides529
5C12NMicroorganisms, enzymes384
6G01NInvestigating / analysing materials358
7C07CAcyclic and carbocyclic compounds251
8Y02AClimate change adaptation230
9C08LPolymer compositions (blends)219
10C09DCoatings, paints, varnishes153

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
PINAVARIUM BROMURE AND MEDAZEPAM COMBINATION FOR IBS TREATMENT2017ABDI IBRAHIM ILAC SANAYI VE TICARET ANONIM SIRKETI1
A COMPRESSED SOLID ORAL DOSAGE FORM COMPRISING PINAVERIUM AND MEDAZEPAM2023ABDI IBRAHIM ILAC SANAYI VE TICARET ANONIM SIRKETI0
FILM COATED TABLET FORMULATIONS CONTAINING BUTYLSCOPOLAMINIUM BROMIDE AND MEDAZEPAM WITH IMPROVED DISSOLVING SPEED2022WORLD MEDICINE ILAC SAN VE TIC A S0
MEDAZEPAM AND PROPANTHELINE COMPOSITION1973F Hoffmann La Roche AG0
PHARMACEUTICAL COMPOSITIONS CONTAINING MEDAZEPAM AND AMITRIPTYLINE1970SPARAMEDICA AG0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Attention Deficit Hyperactivity Disorder1
2Electroconvulsive Therapy Studies1
3Epilepsy research and treatment1
4Foot and Ankle Surgery1
5Hypothalamic control of reproductive hormones1
6Nitric Oxide and Endothelin Effects1

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

See Cypris in action

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1S ManmaruTokyo Medical and Dental University4
2Т. А. ВоронинаSemenov Institute of Chemical Physics4
3Christian Stumpf3
4K Náhunek3
5Malcolm LaderInstitute of Psychiatry and Neurology3
6Petkov Vv3
7A. O. ShepelyakovskayaInstitute of Bioorganic Chemistry2
8Akira HaraGifu Pharmaceutical University2
9Alyson J. BondInstitute of Psychiatry and Neurology2
10Andrejus ŽevžikovasKauno Mišku ir Aplinkos Inžinerijos Kolegija2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Medazepam?

Medazepam has the molecular formula C16H15ClN2 with a molecular weight of 270.76 g/mol. Its canonical chemical name is 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepine, and it is also known by numerous trade names including Nobrial, Elbrus, and Rudotel.

Which pharmaceutical companies hold the most patents related to Medazepam?

The leading patent assignees in the Medazepam field are Takeda Pharmaceutical Co Ltd with 241 patents, Grünenthal GmbH with 182 patents, and Capsugel Belgium NV with 101 patents.

What combination therapies have been patented for Medazepam?

Recent patents describe Medazepam in combination with other active ingredients. A compressed solid oral dosage form combining pinaverium and Medazepam was patented in 2023. Earlier patents from the 1970s describe Medazepam combined with propantheline, and Medazepam with amitriptyline in pharmaceutical compositions.

What is the primary research focus in patents covering Medazepam?

The largest proportion of Medazepam-related patents falls under CPC subclass A61K with 3,537 patents, which covers pharmaceutical formulations and dosage forms. This is followed by A61P with 2,791 patents, which covers pharmaceutical therapeutic applications. Organic chemistry synthesis (C07D) accounts for 871 patents in the field.

Has recent scientific literature studied Medazepam safety during pregnancy?

Yes, a population-based case–control teratologic study published in 2002 examined medazepam treatment during pregnancy alongside other benzodiazepines including nitrazepam, tofisopam, alprazolum, and clonazepam. This study received 96 citations.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial