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Androstenedione

(8R,9S,10R,13S,14S)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione · also: Andro · adione · Androtex · Fecundin · Androstendione · 4-Androstenedione

FormulaC19H26O2
Mol. weight286.415
PubChem CID6128
InChIKeyAEMFNILZOJDQLW-QAGGRKNESA-N
SMILESC[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C
19,294Patents
9,005Research papers8,998 indexed in detail
1,554Patents - last 3 years
136Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Novartis AG960
2Pfizer Inc454
3Bayer AG376
4Johnson and Johnson362
5Roche Holding AG327
6Merck and Co Inc257
7Takeda Pharmaceutical Co Ltd240
8Ipsen SA166
9Kymera Therapeutics Inc161
10Cartesian Therapeutics Inc154

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)11,411
2A61KMedicinal preparations10,660
3C07DHeterocyclic compounds4,630
4C07J2,812
5G01NInvestigating / analysing materials2,282
6C12NMicroorganisms, enzymes1,703
7C07KPeptides1,468
8C12PFermentation, enzyme processes1,047
9C12QMeasuring/testing involving enzymes987
10C07CAcyclic and carbocyclic compounds913

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
4-SUBSTITUTED ANDROSTENDIONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION1986Pfizer Inc30
4-amino androstendione derivatives and process for their preparation1988Pfizer Inc29
Method for preparing androstenedione by biodegradation of phytosterol in two-liquid-phase system200918
Extraction of 4-androstenedione from oil phase of fermenting liquid200518
Biofermentation method for androstendione by using resting cell201017

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
201687
201783
201853
201967
202059
202161
202287
202369
202447
202520

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Mitch DowsettRoyal Marsden Hospital66
2Frank Z. StanczykUniversity of Southern California61
3Fernand LabrieUniversité Laval39
4R. J. ScaramuzziCommonwealth Scientific and Industrial Research Organisation33
5L StárkaInstitute of Endocrinology28
6Jan-Ακε GustafssonKarolinska Institutet25
7Mitsuteru NumazawaTohoku Medical and Pharmaceutical University23
8L. J. SpicerOklahoma State University22
9Van Luu‐TheUniversité Laval18
10Per Eystein LønningHaukeland University Hospital18

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of androstenedione?

Androstenedione has the molecular formula C19H26O2 and a molecular weight of 286.415 g/mol.

Which companies hold the largest patent portfolios for androstenedione?

The leading patent assignees for androstenedione are Novartis AG with 960 patents, Pfizer Inc with 454 patents, and Bayer AG with 376 patents.

What are the most-cited research papers on androstenedione and their primary topics?

The highest-cited papers include a 2006 work on prostate cancer treatment with 1,085 citations, a 2002 review on obesity and endometrial cancer risk with 1,042 citations, and a 2005 study on androgen levels in adult females with 1,000 citations. These papers cover topics including prostate cancer research, ovarian function, and hormonal disorders.

Who are the most prolific authors publishing on androstenedione?

The most active researchers include Mitch Dowsett from Royal Marsden Hospital with 66 papers, Frank Z. Stanczyk from University of Southern California with 61 papers, and Fernand Labrie from Université Laval with 39 papers.

What are the dominant patent classifications for androstenedione technology?

The most common patent classifications are A61P (pharmaceutical preparations for specific therapeutic purposes) with 11,411 patents, A61K (preparations for medical purposes) with 10,660 patents, and C07D (heterocyclic compounds) with 4,630 patents.

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