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Andro

(8R,9S,10R,13S,14S)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione · also: adione, A-dione, Androtex, Fecundin, Androstendione, androstenedione

FormulaC19H26O2
Mol. weight286.415
PubChem CID6128
InChIKeyAEMFNILZOJDQLW-QAGGRKNESA-N
SMILESC[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C
19,294Patents
9,005Research papers
1,719Patents - last 3 years
134Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Novartis AG958
2Janssen Pharmaceutica NV345
3Bayer Pharma AG329
4Takeda Pharmaceutical Co Ltd205
5F Hoffmann La Roche AG182
6Pharmacia and Upjohn Co180
7Cartesian Therapeutics Inc136
8Kymera Therapeutics Inc124
9Sterix Ltd122
10Amgen Inc112

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)11,408
2A61KMedicinal preparations10,657
3C07DHeterocyclic compounds4,630
4C07J2,812
5G01NInvestigating / analysing materials2,278
6C12NMicroorganisms, enzymes1,703
7C07KPeptides1,468
8C12PFermentation, enzyme processes1,047
9C12QMeasuring/testing involving enzymes987
10C07CAcyclic and carbocyclic compounds913

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
SELECTIVE MICROBIOLOGICAL PREPARATION OF ANDROST-4-ENE-3,17-DIONE1973GD Searle LLC73
6-substituted androsta-1,4-diene-3,17-diones1989Pfizer Italia SRL71
Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis1980BRODIE, ANGELA M56
Substituted androsta-1,4-diene-3,17-diones1990Pfizer Italia SRL37
Androst-4-ene-3,17-diones and process for their preparation1989Pfizer Italia SRL25

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Hormonal and reproductive studies40
2Ovarian function and disorders27
3Estrogen and related hormone effects22
4Sexual Differentiation and Disorders10
5Reproductive Physiology in Livestock8
6Reproductive Biology and Fertility7
7Hormonal Regulation and Hypertension5
8Cancer Risks and Factors4
9Sexual function and dysfunction studies4
10Sperm and Testicular Function4

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Frank Z. StanczykUniversity of Southern California60
2Mitch DowsettRoyal Marsden Hospital57
3Fernand LabrieUniversité Laval56
4Christopher LongcopeUniversity of Massachusetts Chan Medical School30
5Jan-Ακε GustafssonKarolinska Institutet29
6R. J. ScaramuzziCommonwealth Scientific and Industrial Research Organisation28
7Angela BrodieUniversity of Maryland, Baltimore26
8L StárkaInstitute of Endocrinology26
9Mitsuteru NumazawaTohoku Medical and Pharmaceutical University25
10L. J. SpicerOklahoma State University22

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Andro?

Andro has the molecular formula C19H26O2 with a molecular weight of 286.415. Its canonical chemical name is (8R,9S,10R,13S,14S)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione, and it is also known by several synonyms including androstenedione, A-dione, and Androstendione.

Which organizations hold the most patents related to Andro?

Novartis AG leads with 958 patents, followed by Janssen Pharmaceutica NV with 345 patents, Bayer Pharma AG with 329 patents, Takeda Pharmaceutical Co Ltd with 205 patents, and F Hoffmann La Roche AG with 182 patents.

What research topics are most prominent in the scientific literature on Andro?

The most frequently studied topics are hormonal and reproductive studies with 40 papers, followed by ovarian function and disorders with 27 papers, and estrogen and related hormone effects with 22 papers. Additional research areas include sexual differentiation and disorders, reproductive physiology in livestock, and reproductive biology and fertility.

What are the most-cited publications about Andro and its biological roles?

The highest-cited papers include a 2006 study on increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer (1076 citations), a 2002 synthetic review on obesity, endogenous hormones, and endometrial cancer risk (1041 citations), and a 2005 study on androgen levels in adult females with changes due to age, menopause, and oophorectomy (991 citations).

How has research and patenting activity on Andro changed in recent years?

Patent activity has remained relatively steady, with 866 patents in 2023 and 768 in 2024, compared to 1,719 patents filed in the last three years overall. Scientific publications show similar trends, with 69 papers in 2023 and 45 in 2024, totaling 134 papers in the last three years. The aggregate covers a total of 19,294 patents and 9,005 papers on this compound.

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