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alpha-Vetivone

(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methylpurin-9-yl)oxolane-3,4-diol

FormulaC11H15N5O4
Mol. weight281.272
PubChem CID27476
InChIKeyGFYLSDSUCHVORB-IOSLPCCCSA-N
SMILESCN1C=NC2=C(C1=N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
4,719Patents
129Research papers
1,233Patents - last 3 years
12Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1ModernaTx Inc374
2Curevac SE249
3GlaxoSmithKline Biologicals SA129
4Pangu Biopharma Ltd123
5aTyr Pharma Inc117
6University of Pennsylvania83
7Moderna Inc79
8Thermo Fisher Scientific Inc72
9Harvard University69
10Dharmacon Inc61

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C12NMicroorganisms, enzymes3,222
2A61KMedicinal preparations3,133
3A61PTherapeutic activity (drug indications)2,655
4C07KPeptides1,500
5C12QMeasuring/testing involving enzymes705
6C12YEnzyme nomenclature (EC numbers)671
7G01NInvestigating / analysing materials596
8C07HSugars and derivatives447
9Y02AClimate change adaptation404
10C12PFermentation, enzyme processes259

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Geography and Environmental Studies1
2RNA and protein synthesis mechanisms1
3RNA modifications and cancer1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Michinao MizugakiTohoku University Hospital10
2Kunihiko ItohTohoku University Hospital9
3Nakao IshidaTohoku University9
4Chengqi YiPeking University5
5Chuan HeUniversity of Chicago5
6Qing DaiUniversity of Chicago5
7Shunji IshiwataTohoku University Hospital5
8Claudia HöbartnerUniversity of Würzburg3
9Dan DominissiniTel Aviv University3
10Eikan MishimaTohoku University3

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

TitleYearCited byTopic
Post-transcriptional gene regulation by mRNA modifications20162551RNA and protein synthesis mechanisms
The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA20161053RNA and protein synthesis mechanisms
Transcriptome-wide mapping reveals reversible and dynamic N1-methyladenosine methylome2016710Cancer-related molecular mechanisms research
The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution2017663Cancer-related molecular mechanisms research
ALKBH1-Mediated tRNA Demethylation Regulates Translation2016592Epigenetics and DNA Methylation

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of alpha-Vetivone?

Alpha-Vetivone has the molecular formula C11H15N5O4 with a molecular weight of 281.272. Its canonical IUPAC name is (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methylpurin-9-yl)oxolane-3,4-diol, and it is identified by the InChI Key GFYLSDSUCHVORB-IOSLPCCCSA-N.

Which organizations hold the most patents related to alpha-Vetivone?

ModernaTx Inc leads with 374 patents, followed by Curevac SE with 249 patents and GlaxoSmithKline Biologicals SA with 129 patents. Other significant patent holders include Pangu Biopharma Ltd, aTyr Pharma Inc, and University of Pennsylvania Penn.

What research areas dominate the patent landscape for alpha-Vetivone?

The most prevalent CPC subclasses are C12N (3,220 patents), A61K (3,133 patents), and A61P (2,654 patents), indicating concentration in biotechnology, pharmaceutical preparations, and medicinal chemistry. Additional significant areas include C07K (protein chemistry) and C12Q (molecular biology techniques).

What are the most cited papers associated with alpha-Vetivone research?

The highest-impact papers include 'Post-transcriptional gene regulation by mRNA modifications' (2,517 citations), 'The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA' (1,036 citations), and 'Transcriptome-wide mapping reveals reversible and dynamic N1-methyladenosine methylome' (702 citations). These works focus on RNA and protein synthesis mechanisms and cancer-related molecular mechanisms.

How has patent activity around alpha-Vetivone evolved in recent years?

Patent filings show significant growth, with 237 patents filed in 2020, increasing to 601 in 2023 and 654 in 2024. The last three years (2023-2025) account for 1,247 of the total 4,719 patents, indicating accelerating development activity in this area.

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