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Adoair

[(6S,8S,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate;2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol · also: Advair, Seroflo, Seretide, Wixela Inhub, Advair Diskus, Seretide Diskus

FormulaC50H68F3NO9S
Mol. weight916.1472
PubChem CID56841124
InChIKeyYYAZJTUGSQOFHG-IAVNQIGZSA-N
SMILESCCC(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H](C3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)SCF.C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O
3,520Patents
481Research papers
239Patents - last 3 years
28Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Galapagos NV119
2AbbVie Inc106
3Chiesi Farmaceutici SpA89
4Gilead Sciences Inc84
5Merck Sharp and Dohme LLC76
6Intellikine LLC56
7Glaxo Group Ltd49
8Amira Pharmaceuticals Inc46
9Aquestive Therapeutics Inc46
10Merck Canada Inc46

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)2,758
2A61KMedicinal preparations2,585
3C07DHeterocyclic compounds1,359
4C07KPeptides690
5A61MDevices for introducing media into the body457
6Y02AClimate change adaptation425
7G01NInvestigating / analysing materials285
8C07FOrganometallic compounds212
9C07BGeneral methods of organic chemistry173
10C12NMicroorganisms, enzymes153

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Asthma and respiratory diseases7
2Chronic Obstructive Pulmonary Disease (COPD) Research4
3Inhalation and Respiratory Drug Delivery1
4Medical Research and Treatments1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Amanda EmmettResearch Triangle Park Foundation11
2Anand A. DalalResearch Triangle Park Foundation11
3Dave SinghUniversity of Manchester11
4Donald BanerjiNovartis (United States)11
5Claus VogelmeierPhilipps University of Marburg10
6Francesco PatalanoNovartis (Switzerland)9
7Jadwiga A. WedzichaImperial College London8
8Brian J. LipworthUniversity of Dundee7
9David A. StempelResearch Triangle Park Foundation7
10David PriceUniversity of Aberdeen6

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Adoair?

Adoair has the molecular formula C50H68F3NO9S with a molecular weight of 916.1472 Da. Its InChI Key is YYAZJTUGSOFHG-IAVNQIGZSA-N. The compound is a combination drug containing fluticasone propionate and salmeterol.

What are the main research topics associated with Adoair in the scientific literature?

The primary research focus is Asthma and respiratory diseases, which accounts for 7 papers in the collection. A secondary focus is Chronic Obstructive Pulmonary Disease (COPD) Research with 4 papers. Additional topics include Inhalation and Respiratory Drug Delivery and Medical Research and Treatments.

Which organizations hold the most patents related to Adoair?

Galapagos NV leads with 119 patents, followed by AbbVie Inc with 106 patents and Chiesi Farmaceutici SpA with 89 patents. Other significant patent holders include Gilead Sciences Inc with 84 patents and Merck Sharp and Dohme LLC with 76 patents.

What is the patent landscape trend for Adoair in recent years?

Total patent coverage stands at 3,520 patents with 239 filed in the last 3 years. Patent filings show a declining trend from 281 patents in 2016 to only 6 patents in 2026. The highest activity was in 2016, with notable decreases observed from 2021 onwards.

Which highly-cited studies have examined Adoair's efficacy?

Key studies include a 2002 paper on Effectiveness of Fluticasone Propionate and Salmeterol Combination Delivered via the Diskus Device in the Treatment of Chronic Obstructive Pulmonary Disease with 507 citations, and a 2012 randomised trial comparing QVA149 with salmeterol–fluticasone in COPD patients with 315 citations. A 2015 study on Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD received 325 citations.

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