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Adoair

[(6S,8S,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate;2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol · also: Seroflo, Seretide, Wixela Inhub, Seretide Diskus, AirDuo Digihaler, AirDuo RespiClick

FormulaC50H68F3NO9S
Mol. weight916.1472
PubChem CID56841124
InChIKeyYYAZJTUGSQOFHG-IAVNQIGZSA-N
SMILESCCC(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H](C3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)SCF.C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O
3,520Patents
481Research papers
223Patents - last 3 years
28Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Galapagos NV119
2AbbVie Inc106
3Chiesi Farmaceutici SpA89
4Gilead Sciences Inc84
5Merck Sharp & Dohme LLC76
6Intellikine LLC56
7Glaxo Group Ltd49
8Amira Pharmaceuticals Inc46
9Aquestive Therapeutics Inc46
10Merck Canada Inc46

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)2,758
2A61KMedicinal preparations2,585
3C07DHeterocyclic compounds1,359
4C07KPeptides690
5A61MDevices for introducing media into the body457
6Y02AClimate change adaptation425
7G01NInvestigating / analysing materials285
8C07FOrganometallic compounds212
9C07BGeneral methods of organic chemistry173
10C12NMicroorganisms, enzymes153

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Asthma and respiratory diseases9
2Chronic Obstructive Pulmonary Disease (COPD) Research5
3Inhalation and Respiratory Drug Delivery2
4Medical Research and Treatments1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Amanda EmmettResearch Triangle Park Foundation12
2Anand A. DalalResearch Triangle Park Foundation11
3Dave SinghUniversity of Manchester11
4Donald BanerjiNovartis (United States)11
5Claus VogelmeierPhilipps University of Marburg10
6Francesco PatalanoNovartis (Switzerland)9
7Jadwiga A. WedzichaImperial College London8
8Brian J. LipworthNinewells Hospital7
9David A. StempelResearch Triangle Park Foundation7
10David PriceUniversity of Aberdeen6

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition and weight of Adoair?

Adoair has the molecular formula C50H68F3NO9S with a molecular weight of 916.1472. The compound is a combination drug containing two active components: fluticasone propionate and salmeterol.

What are the main patent assignees associated with Adoair-related innovations?

The leading patent assignees in the Adoair landscape include Galapagos NV (119 patents), AbbVie Inc (106 patents), Chiesi Farmaceutici SpA (89 patents), Gilead Sciences Inc (84 patents), and Merck Sharp & Dohme LLC (76 patents).

Which research areas dominate the scientific literature on Adoair?

The primary research focus is Asthma and respiratory diseases, which accounts for 9 papers in the literature. Additional significant topics include Chronic Obstructive Pulmonary Disease (COPD) Research (5 papers) and Inhalation and Respiratory Drug Delivery (2 papers).

What are the most-cited published studies on Adoair or closely related compounds?

Highly-cited papers include 'Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist' (884 citations), 'Indacaterol–Glycopyrronium versus Salmeterol–Fluticasone for COPD' (877 citations), and 'Effectiveness of Fluticasone Propionate and Salmeterol Combination Delivered via the Diskus Device in the Treatment of Chronic Obstructive Pulmonary Disease' (508 citations).

How has patenting activity in the Adoair field trended in recent years?

Patent filings peaked in 2016 with 281 patents and have generally declined since then, with 115 patents filed in 2024. The last three years (2022–2024) averaged 161 patents annually. Paper publications show similar decline, with 38 papers in 2016 and only 14 papers in 2024.

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