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Decursinol Angelate

[(3S)-2,2-dimethyl-8-oxo-3,4-dihydropyrano[3,2-g]chromen-3-yl] (Z)-2-methylbut-2-enoate · also: Acutilobin, Decursinolangelate, Decursinol mebutate, Decursinol angelate (Standard), Decursinol angelate - Bio-X trade mark, ((3S)-2,2-dimethyl-8-oxo-3,4-dihydropyrano(3,2-g)chromen-3-yl) (Z)-2-methylbut-2-enoate

FormulaC19H20O5
Mol. weight328.364
PubChem CID776123
InChIKeyAGABNGOXUSXQDD-XKGFZTIGSA-N
SMILESC/C=C(/C)\C(=O)O[C@H]1CC2=C(C=C3C(=C2)C=CC(=O)O3)OC1(C)C
180Patents
153Research papers
39Patents - last 3 years
17Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Cornell University9
2Combangio Inc2
3Princeton University2

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations120
2A61PTherapeutic activity (drug indications)86
3A23LFoods and beverages (general)44
4A23VFoods, foodstuffs - indexing scheme35
5A61QCosmetics, personal care29
6A01NPreservation of bodies; biocides; pest repellents21
7C07HSugars and derivatives13
8C12NMicroorganisms, enzymes10
9C07KPeptides6
10C07FOrganometallic compounds5

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Blood vessel relaxational agent containing decursin or decursinol angelate for the prevention or treatment of blood vessel disease2004KIM, HYUNG HWAN6
Application of decursinol angelate in preparation of anti-atherosclerosis medicine2018RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE4
COMPOSITIONS FOR URINARY DYSFUNCTION AND EDEMA CONTAINING DECURSIN AND/OR DECURSINOL ANGELATE, OR ANGELICA EXTRACT CONTAINING DECURSIN AND /OR DECURSINOL ANGELATE2005CHOI, PAECK-HI3
BLOOD VESSEL RELAXATIONAL AGENT CONTAINING DECURSIN OR DECURSINOL ANGELATE2005KIM, HYUNG HWAN3
COMPOSITION OF TREATMENT FOR VEGF-INDUCED ANGIOGENESIS-RELATED DISEASES CONTAINING DECURSIN AND DECURSINOL ANGELATE2010KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION1

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Plant chemical constituents analysis1
2Retinal Diseases and Treatments1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Gyu‐Yong SongChungnam National University14
2Junxuan LüTexas Tech University Health Sciences Center13
3Cheng JiangUniversity of Minnesota11
4Li LiTexas Tech University Health Sciences Center10
5Chengguo XingUniversity of Minnesota8
6Jinhui ZhangTexas Tech University Health Sciences Center7
7Eun‐Mi AhnDaegu Haany University6
8Hyo‐Jeong LeeKyung Hee University6
9Jung‐woo ChaeChungnam National University5
10Sung‐Hoon KimKyung Hee University5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Decursinol Angelate?

Decursinol Angelate has the molecular formula C19H20O5 and a molecular weight of 328.364 g/mol. Its IUPAC name is [(3S)-2,2-dimethyl-8-oxo-3,4-dihydropyrano[3,2-g]chromen-3-yl] (Z)-2-methylbut-2-enoate.

What are the leading research institutions publishing on Decursinol Angelate?

The most prolific authors in Decursinol Angelate research are affiliated with Chungnam National University, Texas Tech University Health Sciences Center, and University of Minnesota. The author with the highest publication count is affiliated with Chungnam National University with 14 papers.

What are the main patent classification areas for Decursinol Angelate?

The dominant CPC classifications for Decursinol Angelate patents are A61K (pharmaceutical preparations) with 120 patents, A61P (therapeutic applications) with 86 patents, and A23L (food preservation and flavoring) with 44 patents. These reflect its use in pharmaceutical and food applications.

What therapeutic applications are documented in patents for Decursinol Angelate?

Patent applications document several therapeutic uses: blood vessel relaxation and prevention of blood vessel disease, anti-atherosclerosis effects, treatment of urinary dysfunction and edema, and inhibition of VEGF-induced angiogenesis-related diseases. These applications span cardiovascular, renal, and oncology-related indications.

What is the recent trend in patent and publication activity for Decursinol Angelate?

Patent activity has increased significantly, with 21 patents filed in 2024 compared to 6 in 2016. In the last three years (2023–2025), 44 patents and 17 papers have been generated. This reflects growing commercial and research interest in the compound, particularly in 2024.

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