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Acutilobin

[(3S)-2,2-dimethyl-8-oxo-3,4-dihydropyrano[3,2-g]chromen-3-yl] (Z)-2-methylbut-2-enoate · also: Decursinolangelate, Decursinol angelate, Decursinol mebutate, Decursinol angelate - Bio-X trade mark

FormulaC19H20O5
Mol. weight328.364
PubChem CID776123
InChIKeyAGABNGOXUSXQDD-XKGFZTIGSA-N
SMILESC/C=C(/C)\C(=O)O[C@H]1CC2=C(C=C3C(=C2)C=CC(=O)O3)OC1(C)C
180Patents
153Research papers
41Patents - last 3 years
17Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Cornell University9
2Combangio Inc2
3Princeton University2

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations120
2A61PTherapeutic activity (drug indications)86
3A23LFoods and beverages (general)44
4A23VFoods, foodstuffs - indexing scheme35
5A61QCosmetics, personal care29
6A01NPreservation of bodies; biocides; pest repellents21
7C07HSugars and derivatives13
8C12NMicroorganisms, enzymes10
9C07KPeptides6
10C07FOrganometallic compounds5

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Blood vessel relaxational agent containing decursin or decursinol angelate for the prevention or treatment of blood vessel disease2004KIM, HYUNG HWAN6
Application of decursinol angelate in preparation of anti-atherosclerosis medicine2018RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE4
COMPOSITIONS FOR URINARY DYSFUNCTION AND EDEMA CONTAINING DECURSIN AND/OR DECURSINOL ANGELATE, OR ANGELICA EXTRACT CONTAINING DECURSIN AND /OR DECURSINOL ANGELATE2005CHOI, PAECK-HI3
BLOOD VESSEL RELAXATIONAL AGENT CONTAINING DECURSIN OR DECURSINOL ANGELATE2005KIM, HYUNG HWAN3
COMPOSITION OF TREATMENT FOR VEGF-INDUCED ANGIOGENESIS-RELATED DISEASES CONTAINING DECURSIN AND DECURSINOL ANGELATE2010KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION1

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Plant chemical constituents analysis1
2Retinal Diseases and Treatments1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Gyu‐Yong SongChungnam National University14
2Junxuan LüUniversity of Minnesota13
3Cheng JiangUniversity of Minnesota11
4Li LiTexas Tech University Health Sciences Center10
5Chengguo XingUniversity of Minnesota8
6Jinhui ZhangTexas Tech University Health Sciences Center7
7Eun‐Mi AhnDaegu Haany University6
8Hyo‐Jeong LeeKyung Hee University6
9Jung‐woo ChaeChungnam National University5
10Sung‐Hoon KimKyung Hee University5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Acutilobin?

Acutilobin has a molecular formula of C19H20O5 and a molecular weight of 328.364 g/mol. It is also known by several synonyms including Decursinolangelate and Decursinol angelate.

Which institutions hold the most patents related to Acutilobin?

Cornell University holds the most patents related to Acutilobin with 9 patents, followed by Combangio Inc and Princeton University, each with 2 patents.

Who are the most prolific researchers publishing on Acutilobin and their affiliations?

The most prolific researchers are Gyu‐Yong Song from Chungnam National University with 14 papers, Junxuan Lü from University of Minnesota with 13 papers, and Cheng Jiang from University of Minnesota with 11 papers.

What are the primary patent classifications for Acutilobin-related intellectual property?

The primary patent classifications are A61K (120 patents) covering medicinal preparations, A61P (86 patents) covering therapeutic applications, and A23L (44 patents) covering food and beverage processing. These classifications suggest use in pharmaceutical, therapeutic, and food applications.

What patent coverage trends exist for Acutilobin over recent years?

Patent activity has increased substantially, with 41 patents filed in the last 3 years. The year-by-year trend shows growth from 6 patents in 2016 to a peak of 21 patents in 2024. Similarly, academic research has maintained moderate activity with 17 papers in the last 3 years, with notable publications in 2024 (8 papers) and 2025 (5 papers).

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