9-[(4aR,6R,7R,7aR)-2-hydroxy-7-methoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-8-(4-chlorophenyl)sulfanylpurin-6-amine - patents, research & applications

95Patents

104Research papers

23Patents - last 3 years

1Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#	Assignee	Patents
1	Fujifilm Corp	11
2	University of Texas System	6
3	Institut National de la Sante et de la Recherche Medicale INSERM	4
4	4SC AG	3
5	Johns Hopkins University	3

6	Universitair Medisch Centrum Utrecht	3
7	University of Utah Research Foundation Inc	3
8	Cornell Research Foundation Inc	2
9	Tohoku University NUC	2
10	University of Florida	2

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#	Code	Area	Patents
1	`C12N`	Microorganisms, enzymes	58
2	`A61K`	Medicinal preparations	53
3	`A61P`	Therapeutic activity (drug indications)	48
4	`G01N`	Investigating / analysing materials	34
5	`C12Q`	Measuring/testing involving enzymes	18

6	`A61L`	Sterilising / disinfecting materials	10
7	`C07K`	Peptides	9
8	`C07H`	Sugars and derivatives	6
9	`A23L`	Foods and beverages (general)	5
10	`A23V`	Foods, foodstuffs - indexing scheme	5

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#	Research topic	Papers
1	Acute Kidney Injury Research	1
2	Cardiac electrophysiology and arrhythmias	1
3	Chemotherapy-induced organ toxicity mitigation	1
4	Neuroscience of respiration and sleep	1
5	Olfactory and Sensory Function Studies	1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#	Author	Affiliation	Papers
1	Frank Schwede	Biolog Life Science Institute	9
2	George G. Holz	SUNY Upstate Medical University	8
3	Oleg G. Chepurny	SUNY Upstate Medical University	7
4	Colin A. Leech	SUNY Upstate Medical University	6
5	Hans‐Gottfried Genieser	Biolog Life Science Institute	6

6	Igor Dzhura	SUNY Upstate Medical University	6
7	Johannes L. Bos	University Medical Center Utrecht	6
8	Elvira Dzhura	SUNY Upstate Medical University	5
9	Grant G. Kelley	SUNY Upstate Medical University	4
10	Michael W. Roe	SUNY Upstate Medical University	4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Title	Year	Cited by	Topic
Cyclic AMP Potentiates Vascular Endothelial Cadherin-Mediated Cell-Cell Contact To Enhance Endothelial Barrier Function through an Epac-Rap1 Signaling Pathway	2004	414	Nitric Oxide and Endothelin Effects
Epac-selective cAMP Analog 8-pCPT-2′-O-Me-cAMP as a Stimulus for Ca2+-induced Ca2+ Release and Exocytosis in Pancreatic β-Cells	2003	297	Diabetes Treatment and Management
The cAMP binding protein Epac modulates Ca ²⁺ sparks by a Ca ²⁺ /calmodulin kinase signalling pathway in rat cardiac myocytes	2007	207	Cardiac electrophysiology and arrhythmias
Prostaglandin E₂inhibits collagen expression and proliferation in patient-derived normal lung fibroblasts via E prostanoid 2 receptor and cAMP signaling	2006	173	Pulmonary Hypertension Research and Treatments
Protein Kinase B Is Obligatory for Follicle-Stimulating Hormone-Induced Granulosa Cell Differentiation	2003	169	Protein Kinase Regulation and GTPase Signaling

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of this compound?

The compound has a molecular formula of C17H17ClN5O6PS with a molecular weight of 485.8358 g/mol.

Which organizations hold the most patents related to this compound?

Fujifilm Corp holds the largest patent portfolio with 11 patents, followed by University of Texas System with 6 patents, and Institut National de la Sante et de la Recherche Medicale INSERM with 4 patents.

What are the key research areas covered by publications on this compound?

Research covers multiple areas including Nitric Oxide and Endothelin Effects, Diabetes Treatment and Management, Cardiac electrophysiology and arrhythmias, Pulmonary Hypertension Research and Treatments, and Protein Kinase Regulation and GTPase Signaling.

Who are the most prolific authors publishing on this compound?

Frank Schwede from Biolog Life Science Institute has the most publications with 9 papers, followed by George G. Holz from SUNY Upstate Medical University with 8 papers, and Oleg G. Chepurny from SUNY Upstate Medical University with 7 papers.

What is the primary patent classification focus for this compound?

Patents are predominantly classified under C12N (Biotechnology) with 58 patents, followed by A61K (Pharmaceutical preparations) with 53 patents, and A61P (Specific therapeutic activity of chemical compounds or preparations) with 48 patents.