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7-Methylguanosine 5'-triphosphate

[[[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate

FormulaC11H18N5O14P3
Mol. weight537.2073
PubChem CID135659024
InChIKeyDKVRNHPCAOHRSI-KQYNXXCUSA-N
SMILESCN1C=[N+](C2=C1C(=O)NC(=N2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)[O-])O)O
462Patents
63Research papers
53Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1European Molecular Biology Laboratory30
2Sanofi SA25
3Caribou Biosciences Inc24
4Incyte Corp17
5Moderna Inc13
6Nestle SA13
7Roche Holding AG11
8Agency for Science, Technology and Research10
9Beam Therapeutics Inc9
10Cocrystal Pharma Inc9

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations262
2C12NMicroorganisms, enzymes257
3A61PTherapeutic activity (drug indications)242
4C07KPeptides173
5G01NInvestigating / analysing materials67
6C12YEnzyme nomenclature (EC numbers)62
7C07DHeterocyclic compounds56
8Y02AClimate change adaptation56
9C12QMeasuring/testing involving enzymes46
10C12PFermentation, enzyme processes40

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
COMPOSITIONS AND METHODS OF NUCLEIC ACID-TARGETING NUCLEIC ACIDS2014Caribou Biosciences Inc336
Human application of engineered chimeric antigen receptor (CAR) T-cells2017The University of Texas System97
Kits and methods for generating 5′ capped RNA201497
Compositions and methods of nucleic acid-targeting nucleic acids2016Caribou Biosciences Inc74
Intracellular genomic transplant and methods of therapy2019Government of the United States of America35

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20162
20173
20181
20193
20201
20211

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Edward DarżynkiewiczUniversity of Warsaw6
2Jacek JemielityUniversity of Warsaw5
3Robert E. RhoadsNew York University5
4Dixie J. GossHunter College5
5Joanna ZuberekUniversity of Warsaw4
6Ryszard StolarskiUniversity of Warsaw3
7Joanna KowalskaUniversity of Warsaw3
8Janusz StȩpińskiUniversity of Warsaw3
9Michal ShapiraBen-Gurion University of the Negev2
10Nahum SonenbergMcGill University2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of 7-Methylguanosine 5'-triphosphate?

7-Methylguanosine 5'-triphosphate has the molecular formula C11H18N5O14P3 and a molecular weight of 537.2073. Its canonical IUPAC name is [[[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate, with InChI Key DKVRNHPCAOHRSI-KQYNXXCUSA-N.

Which organizations hold the most patents related to this compound?

The leading patent holders are European Molecular Biology Laboratory with 30 patents, Sanofi SA with 25 patents, and Caribou Biosciences Inc with 24 patents. Other significant assignees include Incyte Corp (17 patents), Moderna Inc (13 patents), and Nestle SA (13 patents).

What research areas are most commonly associated with patents on this compound?

Patents covering this compound are predominantly classified under A61K (262 patents), C12N (257 patents), and A61P (242 patents), indicating primary focus on pharmaceutical preparations, biotechnology, and medicinal chemistry applications. Additional significant patent categories include C07K (173 patents) for peptide and protein chemistry and C12Y (62 patents) for enzyme technology.

What is the recent patent activity trend for this compound?

Patent filings peaked in 2021 with 44 patents, followed by 2020 with 38 patents and 2024 with 33 patents. In the last three years (2022–2024), 98 patents were filed. In 2019, 24 patents were filed, showing increasing attention to the compound since that year, with 53 patents filed in the last three years overall.

Which researchers have published the most work on this compound?

Edward Darżynkiewicz from University of Warsaw authored 6 papers on this compound, the most among identified researchers. Jacek Jemielity, also from University of Warsaw, authored 5 papers, as did Robert E. Rhoads from New York University and Dixie J. Goss from Hunter College. Other prolific contributors from University of Warsaw include Joanna Zuberek (4 papers) and Ryszard Stolarski (3 papers).

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