Book a demo

Chemical intelligence powered by cypris.ai

6-(2,6-dichlorophenyl)-8-methyl-2-(3-methylsulfanylanilino)pyrido[2,3-d]pyrimidin-7-one

6-(2,6-dichlorophenyl)-8-methyl-2-(3-methylsulfanylanilino)pyrido[2,3-d]pyrimidin-7-one

FormulaC21H16Cl2N4OS
Mol. weight443.346
PubChem CID447077
InChIKeyVAARYSWULJUGST-UHFFFAOYSA-N
SMILESCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=CC=C3Cl)Cl)NC4=CC(=CC=C4)SC
198Patents
35Research papers
38Patents - last 3 years
2Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Array Biopharma Inc28
2Schroedinger Inc14
3Deciphera Pharmaceuticals LLC10
4Foundation Medicine Inc9
5Memorial Sloan Kettering Cancer Center8
6Emory University7
7Loxo Oncology Inc6
8Scripps Research Institute5
9Yale University4
10Acerta Pharma BV3

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

Visit Cypris

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)169
2A61KMedicinal preparations142
3C07DHeterocyclic compounds89
4C12QMeasuring/testing involving enzymes42
5C07KPeptides35
6C12NMicroorganisms, enzymes35
7G01NInvestigating / analysing materials28
8C12YEnzyme nomenclature (EC numbers)14
9Y02AClimate change adaptation9
10C07BGeneral methods of organic chemistry8

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Ajit JadhavNational Center for Advancing Translational Sciences4
2Anton SimeonovNational Center for Advancing Translational Sciences4
3Alan J. KrakerWarde Medical Laboratory3
4Bayard D. ClarksonMemorial Sloan Kettering Cancer Center3
5Carleen Klumpp‐ThomasNational Center for Advancing Translational Sciences3
6Kelli M. WilsonNational Center for Advancing Translational Sciences3
7Kyle R. BrimacombeNational Center for Advancing Translational Sciences3
8Matthew D. HallNational Institutes of Health3
9Min ShenNational Institutes of Health3
10A StrifeKettering University2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition and weight of this compound?

This compound has the molecular formula C21H16Cl2N4OS and a molecular weight of 443.346 g/mol. It contains two chlorine atoms, four nitrogen atoms, one sulfur atom, and one oxygen atom within its pyrido[2,3-d]pyrimidine core structure.

Which organizations hold the most patents related to this compound?

Array Biopharma Inc holds the largest patent portfolio with 28 patents, followed by Schroedinger Inc with 14 patents and Deciphera Pharmaceuticals LLC with 10 patents. Other significant patent holders include Foundation Medicine Inc, Memorial Sloan Kettering Cancer Center, and Emory University.

What research areas are most commonly associated with this compound in published literature?

The compound is primarily associated with kinase inhibition research. Key topics include Chronic Lymphocytic Leukemia Research, Protein Kinase Regulation and GTPase Signaling, HER2/EGFR in Cancer Research, and Microtubule and mitosis dynamics. Published work emphasizes its role as a tyrosine kinase inhibitor, particularly targeting c-Src and Bcr-Abl.

How is intellectual property protection structured for this compound across chemical and pharmaceutical domains?

Patent protection spans multiple classification areas. The largest patent coverage is under A61P (medicinal preparations for specific therapies) with 169 patents, followed by A61K (preparations for medical purposes) with 142 patents. Chemical synthesis and characterization are covered under C07D (heterocyclic compounds) with 89 patents, while diagnostic and testing applications appear under C12Q and G01N with 42 and 28 patents respectively.

What is the recent patent activity trend for this compound?

Patent filings have shown significant activity over the past decade, with a notable peak in 2022 with 23 patents filed. The three-year period from 2022-2024 accounts for 59 of the 198 total patents (approximately 30%), indicating sustained research and development interest. Recent years (2024-2025) show 31 patents, demonstrating continued active patent filing.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial