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5-methoxy-2-phenylchromen-4-one

5-methoxy-2-phenylchromen-4-one · also: 5-Methoxyflavone · 5-Methoxy-2-phenyl-chromen-4-one · 5-Methoxy-2-phenyl chromen-4-one · 5-Methoxy-2-phenyl-4-benzopyrone · 5-methoxy-2-phenyl-4h-chromen-4-one · 5-Methoxy-2-phenyl-4H-1-benzopyran-4-one

FormulaC16H12O3
Mol. weight252.269
PubChem CID94525
InChIKeyXRQSPUXANRGDAV-UHFFFAOYSA-N
SMILESCOC1=CC=CC2=C1C(=O)C=C(O2)C3=CC=CC=C3
83Patents
27Research papers
29Patents - last 3 years
1Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Avantium NV8
2Eli Lilly and Co6
3Goodyear Tire and Rubber Co5
4China National Tobacco Corp3
5Disco Corp3
6Chinese Academy of Sciences2
7Kissei Pharmaceutical Co Ltd2
8Suntory Holdings Ltd2
9The University of Texas System2
10Arakawa Chemical Industries Ltd1

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)33
2A61KMedicinal preparations28
3C07DHeterocyclic compounds20
4C08KPolymer compositions (additives)9
5Y02PClimate change mitigation: production9
6C07BGeneral methods of organic chemistry7
7B01JChemical/physical processes (e.g. catalysts)5
8B60C5
9C07CAcyclic and carbocyclic compounds5
10C08LPolymer compositions (blends)5

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Application of 5-methoxyflavone in preparing medicine for treating obesity, hypercholesterolemia and fatty liver20222
Application of 5-methoxyflavone in preparation of medicine for preventing or treating influenza virus infection20220

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20161
20183
20191
20201
20211
20222
20241

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Janez KoncUniversity of Ljubljana2
2Vijaykumar SayeliMamata Medical College2
3Stanislav GobecUniversity of Ljubljana2
4Thomas WalleMedical University of South Carolina2
5S. ViswanathanMeenakshi Academy of Higher Education and Research2
6Binoy Varghese CheriyanVels University2
7Jure StojanUniversity of Ljubljana2
8Jagan NadipellyTexila American University2
9Tea Lanišnik RižnerUniversity of Ljubljana2
10Parimala KathirveluMeenakshi Academy of Higher Education and Research2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of 5-methoxy-2-phenylchromen-4-one?

5-methoxy-2-phenylchromen-4-one has the molecular formula C16H12O3 and a molecular weight of 252.269. It is also known by several alternative names including 5-Methoxyflavone and 5-Methoxy-2-phenyl-4H-1-benzopyran-4-one.

Which organizations hold the most patents for 5-methoxy-2-phenylchromen-4-one?

Avantium NV leads with 8 patents, followed by Eli Lilly and Co with 6 patents and Goodyear Tire and Rubber Co with 5 patents. Other significant patent holders include China National Tobacco Corp and Disco Corp, each with 3 patents.

What is the trend in patent filings for this compound in recent years?

Patent activity has increased significantly, with 3 patents filed in 2017, rising to 8 in 2021, 12 in 2023, and 14 in 2024. There have been 29 patents filed in the last 3 years, showing strong recent interest in this compound.

What biological activities have been studied for 5-methoxy-2-phenylchromen-4-one?

Published research has demonstrated multiple biological activities: one study identified it as a DNA Polymerase-Beta inhibitor with neuroprotective potential against Beta-Amyloid toxicity, another showed AMPKα activation that inhibits NF-κB and P38 MAPK signaling to attenuate influenza A virus-mediated inflammation and lung injury, and additional research examined phytoestrogen properties and anti-inflammatory activity.

What are the primary patent classification areas for this compound?

Patents involving this compound are predominantly classified under A61P (pharmaceutical preparation use, 33 patents) and A61K (organic chemical compounds for medical use, 28 patents). Additional significant classifications include C07D (heterocyclic compounds, 20 patents) and C08K (polymer additives, 9 patents), reflecting applications in pharmaceuticals, materials science, and industrial chemistry.

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