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5-methoxy-2-phenylchromen-4-one

5-methoxy-2-phenylchromen-4-one · also: 5-Methoxyflavone, Methoxyflavone, 5-(AS), 5-Methoxy-2-phenyl-chromen-4-one, 5-Methoxy-2-phenyl-4-benzopyrone, 5-Methoxy-2-phenyl chromen-4-one, 5-methoxy-2-phenyl-4h-chromen-4-one

FormulaC16H12O3
Mol. weight252.269
PubChem CID94525
InChIKeyXRQSPUXANRGDAV-UHFFFAOYSA-N
SMILESCOC1=CC=CC2=C1C(=O)C=C(O2)C3=CC=CC=C3
83Patents
27Research papers
30Patents - last 3 years
1Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Furanix Technologies BV8
2Eli Lilly and Co6
3Goodyear Tire and Rubber Co5
4Disco Corp3
5China Tobacco Henan Industrial Co Ltd2
6Kissei Pharmaceutical Co Ltd2
7Suntory Holdings Ltd2
8The University of Texas System2
9The University of Texas at Austin2
10Arakawa Chemical Industries Ltd1

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)33
2A61KMedicinal preparations28
3C07DHeterocyclic compounds20
4C08KPolymer compositions (additives)9
5Y02PClimate change mitigation: production9
6C07BGeneral methods of organic chemistry7
7B01JChemical/physical processes (e.g. catalysts)5
8B60C5
9C07CAcyclic and carbocyclic compounds5
10C08LPolymer compositions (blends)5

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Application of 5-methoxyflavone in preparing medicine for treating obesity, hypercholesterolemia and fatty liver2022GUANGXI UNIVERSITY2
Application of 5-methoxyflavone in preparation of medicine for preventing or treating influenza virus infection2022Gaozhou people's hospital0

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Binoy Varghese CheriyanVels University2
2Jagan NadipellyTexila American University2
3Jaikumar ShanmugasundaramMeenakshi Medical College Hospital and Research Institute2
4Janez KoncUniversity of Ljubljana2
5Jure StojanUniversity of Ljubljana2
6Katja KrajncUniversity of Ljubljana2
7Katja KristanUniversity of Ljubljana2
8Parimala KathirveluMeenakshi Academy of Higher Education and Research2
9S. ViswanathanMeenakshi Academy of Higher Education and Research2
10Stanislav GobecUniversity of Ljubljana2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of 5-methoxy-2-phenylchromen-4-one?

5-methoxy-2-phenylchromen-4-one has the molecular formula C16H12O3 and a molecular weight of 252.269. It is also known by several synonyms including 5-methoxyflavone and 5-methoxy-2-phenyl-4H-chromen-4-one.

Which organizations hold the most patents for this compound?

Furanix Technologies BV holds the largest patent portfolio with 8 patents, followed by Eli Lilly and Co with 6 patents and Goodyear Tire and Rubber Co with 5 patents covering this compound.

What bioactive properties have been documented in recent research?

Recent studies demonstrate multiple bioactive properties: 5-methoxyflavone-induced AMPKα activation inhibits NF-κB and P38 MAPK signaling to attenuate influenza A virus-mediated inflammation and lung injury in vitro and in vivo; it has been identified as a novel DNA polymerase-beta inhibitor with neuroprotective activity against beta-amyloid toxicity; and phytoestrogens containing this compound function as inhibitors of fungal 17β-hydroxysteroid dehydrogenase.

What therapeutic applications are covered in recent patent filings?

Recent patent applications describe the use of 5-methoxyflavone in preparing medicines for treating obesity, hypercholesterolemia, and fatty liver disease, as well as for preventing or treating influenza virus infection.

How has patent activity for this compound evolved in recent years?

Patent activity has increased significantly, with 30 patents filed in the last 3 years. The trend shows growth from 1 patent in 2020 to 14 patents in 2024, with 10 patents filed through 2025. The primary patent classification areas are A61P (pharmaceutical preparations) and A61K (pharmaceutical preparations), accounting for 33 and 28 patents respectively.

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