Compounds

5-HMF

IUPAC
5-(hydroxymethyl)furan-2-carbaldehyde
Formula
C6H6O3
MW
126.111 g/mol
InChIKey
NOEGNKMFWQHSLB-UHFFFAOYSA-N
SMILES
C1=C(OC(=C1)C=O)CO
PubChem CID
237332

22,992 patents · 1,509 papers · 4,050 patents and 126 papers in the last 3 years.

Top assignees

  1. Archer Daniels Midland Co (443 patents)
  2. Dalian Institute of Chemical Physics of CAS (389 patents)
  3. Furanix Technologies BV (338 patents)

Notable patents

  1. Process for the oxidation of 5-hydroxymethylfurfural (1990)
  2. Process for preparing pure 5-hydroxymethylfurfuraldehyde (1988)
  3. Production of 5-hydroxymethylfurfural (1960)

Notable papers

  1. Metal Chlorides in Ionic Liquid Solvents Convert Sugars to 5-Hydroxymethylfurfural (2007)
  2. Phase Modifiers Promote Efficient Production of Hydroxymethylfurfural from Fructose (2006)
  3. The mechanism for thermal decomposition of cellulose and its main products (2009)

Full landscape: every top assignee, author, patent, paper, and classification.

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Top assignees

AssigneePatents
Archer Daniels Midland Co443
Dalian Institute of Chemical Physics of CAS389
Furanix Technologies BV338
Novozymes Inc327
BASF SE320
IFP Energies Nouvelles IFPEN252
Novozymes AS227
China Petroleum and Chemical Corp217
Shell Internationale Research Maatschappij BV205
Eastman Chemical Co151

Top authors

AuthorAffiliationPapers
Anders WieslanderLund University10
Baochang CaiNanjing University of Chinese Medicine8
Cristina Delgado‐AndradeEstación Experimental del Zaidín8
Bärbel Hahn‐HägerdalLund University7
Ann Van LoeyKU Leuven6
Avelino CormaUniversitat Politècnica de València6
Burçe Ataç MogolHacettepe University6
Vural GökmenHacettepe University6
Andrea B. MaierMedical University of Graz5
Bernhard H. MonienGerman Institute of Human Nutrition5

Top patents

TitleYearAssigneeCitations
Process for the oxidation of 5-hydroxymethylfurfural1990Hoechst AG128
Process for preparing pure 5-hydroxymethylfurfuraldehyde1988SUDDEUTSCHE ZUCKER-AKTIENGESELLSCHAFT101
Production of 5-hydroxymethylfurfural1960Merck and Co Inc90
Process for manufacturing 5-hydroxymethylfurfural1986Roquette Freres SA81
Process for manufacturing 5-hydroxymethylfurfural1982Roquette Freres SA73

Top papers

TitleYearCitationsTopic
Metal Chlorides in Ionic Liquid Solvents Convert Sugars to 5-Hydroxymethylfurfural20071974Ionic liquids properties and applications
Phase Modifiers Promote Efficient Production of Hydroxymethylfurfural from Fructose20061655Supercapacitor Materials and Fabrication
The mechanism for thermal decomposition of cellulose and its main products2009965Thermochemical Biomass Conversion Processes
Ionic Liquid-Mediated Formation of 5-Hydroxymethylfurfural—A Promising Biomass-Derived Building Block2010789Ionic liquids properties and applications
Mechanism of formation of 5-(hydroxymethyl)-2-furaldehyde from d-fructose and sucrose1990764Biofuel production and bioconversion

Patent classifications

CodeAreaPatents
C07DHeterocyclic compounds6,146
Y02EClimate change mitigation: energy4,054
C12PFermentation, enzyme processes4,047
B01JChemical/physical processes (e.g. catalysts)3,390
Y02PClimate change mitigation: production3,077
C07CAcyclic and carbocyclic compounds2,481
C12NMicroorganisms, enzymes2,143
A61KMedicinal preparations1,910
C08GPolymers from non-vinyl bonds (e.g. polyamides, polyesters)1,573
C13K1,532

Research topics

TopicPapers
Catalysis for Biomass Conversion6
Advanced Glycation End Products research5
Biofuel production and bioconversion4
Bee Products Chemical Analysis3
Phytochemicals and Antioxidant Activities2
Anaerobic Digestion and Biogas Production1
Carcinogens and Genotoxicity Assessment1
Fermentation and Sensory Analysis1
Natural Antidiabetic Agents Studies1
Natural Products and Biological Research1

Frequently asked questions

What is the molecular structure and chemical formula of 5-HMF?

5-HMF, also known as 5-(hydroxymethyl)furan-2-carbaldehyde, has the molecular formula C6H6O3 and a molecular weight of 126.111. It is also referred to by several synonyms including Hydroxymethylfurfural and Hydroxymethylfurfuraldehyde.

Which organizations hold the largest patent portfolios for 5-HMF?

The leading assignees in 5-HMF patents are Archer Daniels Midland Co with 443 patents, Dalian Institute of Chemical Physics of CAS with 389 patents, Furanix Technologies BV with 338 patents, Novozymes Inc with 327 patents, and BASF SE with 320 patents.

What are the most significant research topics associated with 5-HMF?

The primary research focus is Catalysis for Biomass Conversion, which accounts for 6 papers. Other major topics include Advanced Glycation End Products research with 5 papers and Biofuel production and bioconversion with 4 papers.

Which patent classes dominate 5-HMF intellectual property?

The most prevalent CPC subclasses for 5-HMF patents are C07D (heterocyclic compounds) with 6146 patents, Y02E (energy generation from renewable sources) with 4054 patents, and C12P (biotechnology processes) with 4047 patents.

What has been the trend in 5-HMF patent and publication activity in recent years?

Patent activity has shown growth, with 1770 patents filed in 2024 compared to 1277 in 2019, and the last three years (2022-2024) averaging approximately 1699 patents annually. Paper publication has been more variable, with 42 papers published in 2024 following a peak of 95 papers in 2022.