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4,17 Beta-dihydroxy-4-androstene-3-one

(8R,9S,10R,13S,14S,17S)-4,17-dihydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one · also: 4-Hydroxytestosterone · 4-Hydroxy Testosterone · 4-hydroxy-testosterone · 4,17beta-dihydroxyandrost-4-en-3-one · 4-Androstene-7alpha-17beta-diol-3-one · 4,17beta-Dihydroxy-4-androstene-3-one

FormulaC19H28O3
Mol. weight304.43
PubChem CID160615
InChIKeyBQOIJSIMMIDHMO-FBPKJDBXSA-N
SMILESC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C(C(=O)CC[C@]34C)O
250Patents
38Research papers
8Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Pfizer Inc36
2Imperial Brands PLC16
3Intelligent Bio Solutions Inc10
4Danaher Corp9
5Research Foundation of the State University of New York8
6University of London8
7Harvard University7
8Massachusetts Institute of Technology6
9Bayer AG4
10Medtronic PLC3

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations159
2A61PTherapeutic activity (drug indications)153
3C07J47
4G01NInvestigating / analysing materials40
5C07DHeterocyclic compounds30
6Y02AClimate change adaptation20
7A24F19
8A61MDevices for introducing media into the body19
9B82YNanotechnology15
10A24B13

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
4-hydroxytestosterone and esters thereof1956Pfizer Inc31
USE OF 4-HYDROXYTESTOSTERONE AS ANGIOGENESIS INHIBITOR20220

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20171
20183
20201

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Carolyn M. KlingeUniversity of Louisville3
2Boudewijn BurgeringUniversity Medical Center Utrecht2
3Wilhelm SchänzerGerman Sport University Cologne2
4René H. MedemaUniversity Medical Center Utrecht2
5Eric W.‐F. LamLudwig Cancer Research2
6J. C. MittlerVeterans Biomedical Research Institute2
7Maria Kristina ParrUniversity of Cologne2
8Linda CheungUniversity of Warwick1
9Penn MuluhngwiUniversity of Louisville1
10Stella PelengarisUniversity of Warwick1

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of 4,17 Beta-dihydroxy-4-androstene-3-one?

The compound has a molecular formula of C19H28O3 and a molecular weight of 304.43.

Which organizations hold the most patents related to this compound?

Pfizer Inc holds the most patents with 36, followed by Imperial Brands PLC with 16 patents, and Intelligent Bio Solutions Inc with 10 patents.

What are the main patent classification areas for this compound?

The compound is primarily classified under A61K (159 patents) for pharmaceutical formulations, A61P (153 patents) for therapeutic applications, and C07J (47 patents) for steroid chemistry.

When was the earliest patent for 4-hydroxytestosterone filed, and by whom?

The earliest patent on record is US-2762818-A titled '4-hydroxytestosterone and esters thereof,' filed in 1956 and assigned to Pfizer Inc.

Who are the most prolific authors publishing research on this compound?

Carolyn M. Klinge from University of Louisville is the most prolific author with 3 papers, followed by several authors with 2 papers each including Boudewijn Burgering from University Medical Center Utrecht and Wilhelm Schänzer from German Sport University Cologne.

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