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(3S,5R)-3-(dimethylamino)-1,5-dihydroxyhexan-2-one

(3S,5R)-3-(dimethylamino)-1,5-dihydroxyhexan-2-one

FormulaC8H17NO3
Mol. weight175.228
PubChem CID57091830
InChIKeyHWTLJGBYQAPJOF-RQJHMYQMSA-N
SMILESC[C@H](C[C@@H](C(=O)CO)N(C)C)O
357Patents
55Research papers
0Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Pfizer Inc48
2Bristol Myers Squibb Co47
3Abbott Laboratories24
4Selvita SA21
5Cormedix Inc20
6GSK PLC16
7Merck and Co Inc13
8Leland Stanford Junior University10
9Basilea Pharmaceutica AG7
10Enanta Pharmaceuticals Inc7

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C07HSugars and derivatives236
2A61PTherapeutic activity (drug indications)214
3A61KMedicinal preparations97
4C12NMicroorganisms, enzymes85
5C07DHeterocyclic compounds81
6C12PFermentation, enzyme processes77
7C07KPeptides23
8Y02PClimate change mitigation: production23
9C40B14
10Y02AClimate change adaptation11

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Carbohydrate conjugates as delivery agents for oligonucleotides2012Alnylam Pharmaceuticals Inc515
CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES2009Alnylam Pharmaceuticals Inc428
MODIFIED iRNA AGENTS2012Alnylam Pharmaceuticals Inc207
N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor1984Pfizer Inc242
Erythromycins and process for their preparation200191

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Hung‐wen LiuThe University of Texas at Austin10
2Lishan ZhaoUniversity of Minnesota4
3David H. ShermanUniversity of Michigan3
4Hazel M. HoldenUniversity of Wisconsin–Madison3
5E. Sethe BurgieUniversity of Wisconsin–Madison3
6Giorgio CortiNational Research Council3
7Yeo Joon YoonEwha Womans University Medical Center3
8Svetlana A. BorisovaThe University of Texas at Austin3
9Silvio BicciatoUniversity of Modena and Reggio Emilia3
10Mark W. RuszczyckyThe University of Texas at Austin3

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

Which organizations hold the most patents involving this compound?

The leading patent assignees for this compound are Pfizer Inc with 48 patents, Bristol Myers Squibb Co with 47 patents, and Abbott Laboratories with 24 patents. Other significant assignees include Selvita SA with 21 patents and Cormedix Inc with 20 patents.

What is the molecular composition of this compound?

This compound has the molecular formula C8H17NO3 and a molecular weight of 175.228. Its InChI Key is HWTLJGBYQAPJOF-RQJHMYQMSA-N.

Which academic researchers have published the most work related to this compound?

Hung‐wen Liu from The University of Texas at Austin is the leading author with 10 papers. Other prolific researchers include Lishan Zhao from University of Minnesota with 4 papers, followed by David H. Sherman from University of Michigan, Hazel M. Holden from University of Wisconsin–Madison, and E. Sethe Burgie from University of Wisconsin–Madison, each with 3 papers.

What are the primary research areas covered by patents for this compound?

The most significant CPC patent classifications are C07H (236 patents) covering organic compounds, followed by A61P (214 patents) covering therapeutic uses, and A61K (97 patents) covering medicinal preparations. Biotechnology and enzyme-related patents (C12N and C12P) account for 85 and 77 patents respectively.

What notable patent exists covering macrolide-related chemistry with this compound?

US-4474768-A titled "N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor" was issued in 1984 and assigned to Pfizer Inc. It has received 242 citations. Additionally, US-6271255-B1 titled "Erythromycins and process for their preparation" was issued in 2001 with 91 citations.

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