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(3-hydroxy-4-methoxyphenyl)-(3,4,5-trimethoxyphenyl)methanone

(3-hydroxy-4-methoxyphenyl)-(3,4,5-trimethoxyphenyl)methanone

FormulaC17H18O6
Mol. weight318.325
PubChem CID9948888
InChIKeyHSLFWBPRHXGUAN-UHFFFAOYSA-N
SMILESCOC1=C(C=C(C=C1)C(=O)C2=CC(=C(C(=C2)OC)OC)OC)O
267Patents
33Research papers
64Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Cytomx Therapeutics Inc57
2Council of Scientific and Industrial Research12
3Oncternal Therapeutics Inc10
4University of Tennessee Research Foundation10
5Massachusetts Institute of Technology9
6Memorial Sloan Kettering Cancer Center9
7ETH Zurich8
8Dana Farber Cancer Institute Inc7
9Columbia University6
10AOP Orphan Pharmaceuticals AG4

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)204
2A61KMedicinal preparations197
3C07KPeptides120
4C07DHeterocyclic compounds87
5C07CAcyclic and carbocyclic compounds42
6C07FOrganometallic compounds34
7C07BGeneral methods of organic chemistry19
8G01NInvestigating / analysing materials17
9C12NMicroorganisms, enzymes15
10C12YEnzyme nomenclature (EC numbers)14

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Synthesis and biological activity1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Joëlle DuboisInstitut de Chimie des Substances Naturelles7
2Alina GhinetUniversité de Lille6
3Benoı̂t RigoUniversité de Lille6
4Amaury FarceUniversité de Lille5
5Concepción ÁlvarezUniversidad de Salamanca4
6Elena BîcuAlexandru Ioan Cuza University4
7Ernest HamelNational Institutes of Health4
8Manuel MedardeUniversidad de Salamanca4
9Philippe GautretUniversité de Lille4
10Rafael PeláezUniversidad de Salamanca4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of this compound?

The compound has a molecular formula of C17H18O6 and a molecular weight of 318.325 g/mol.

Which organization holds the most patents related to this compound?

Cytomx Therapeutics Inc holds the most patents related to this compound, with 57 patent records.

What are the primary research areas covered by patents for this compound?

The primary research areas are pharmaceutical and medicinal applications, reflected in the leading CPC subclasses: pharmaceutical preparations and medicinal compounds (A61P with 204 patents and A61K with 197 patents), followed by organic chemistry synthesis methods (C07K with 120 patents and C07D with 87 patents).

What biological activities has this compound been investigated for?

Published research indicates the compound has been evaluated as a tubulin polymerization inhibitor and anticancer agent. Specific studies include synthesis and biological evaluation in phenstatin-based anticancer agents, incorporation into platinum(IV) complexes as microtubule polymerization inhibitors and multidrug resistance reversers, and development as part of hybrid molecules for tubulin polymerization inhibition.

How has patent activity for this compound trended in recent years?

Patent activity has generally increased, with 28 patents filed in 2024 and 23 in 2023, representing peaks in the dataset. Activity peaked again in 2021 with 21 patents. Over the full period from 2016 to 2026, patent counts have fluctuated, with recent years showing higher filing rates compared to 2017-2019, when annual filings ranged from 7 to 20 patents.

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