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1H-imidazol-2-yl (2S)-2-amino-3-(1H-imidazol-5-yl)propanoate

1H-imidazol-2-yl (2S)-2-amino-3-(1H-imidazol-5-yl)propanoate

FormulaC9H11N5O2
Mol. weight221.22
PubChem CID57046064
InChIKeyNQZRBPJAHUOTAF-ZETCQYMHSA-N
SMILESC1=CN=C(N1)OC(=O)[C@H](CC2=CN=CN2)N
379Patents
63Research papers
11Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Government of the United States of America23
2Battelle Memorial Institute Inc17
3Roche Holding AG16
4International Flavors and Fragrances Inc14
5Merck and Co Inc12
6Weizmann Institute of Science10
7Berkshire Hathaway Inc8
8Chinese Academy of Sciences7
9Cellectar Biosciences Inc6
10Takeda Pharmaceutical Co Ltd6

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C07KPeptides154
2A61KMedicinal preparations146
3A61PTherapeutic activity (drug indications)121
4G01NInvestigating / analysing materials90
5C12NMicroorganisms, enzymes74
6C07DHeterocyclic compounds52
7C12QMeasuring/testing involving enzymes41
8C12PFermentation, enzyme processes31
9C07CAcyclic and carbocyclic compounds22
10C12YEnzyme nomenclature (EC numbers)21

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
ALPHA-AMYLASE COMBINATORIAL VARIANTS2014International Flavors and Fragrances Inc222
Synthetic peptides useful as universal carriers for the preparation of immunogenic conjugates and their use in the development of synthetic vaccines1991Eni SpA358
SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE201756
Cell delivery compositions2004Massachusetts Institute of Technology104
HINGE DOMAIN ENGINEERING2009AstraZeneca PLC61

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1F. Ann WalkerUniversity of Arizona3
2Masaru MiyagiCase Western Reserve University2
3Rehab F. AbdelhamidIbaraki University2
4Rimma I. SamoilovaInstitute of Chemical Kinetics and Combustion2
5Graham S. JacksonUniversity College London2
6John CollingeUniversity College London2
7Jonathan P. WalthoUniversity of Sheffield2
8Takamitsu KohzumaIbaraki University2
9M A WellsUniversity of Sheffield2
10Sergei A. DikanovUniversity of Illinois Urbana-Champaign2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition and weight of this compound?

The compound has the molecular formula C9H11N5O2 with a molecular weight of 221.22. Its InChI Key is NQZRBPJAHUOTAF-ZETCQYMHSA-N.

Which organizations hold the most patents involving this compound?

The Government of the United States of America leads with 23 patents, followed by Battelle Memorial Institute Inc with 17 patents, and Roche Holding AG with 16 patents. International Flavors and Fragrances Inc and Merck and Co Inc round out the top five with 14 and 12 patents respectively.

What research topics are most commonly associated with this compound in the academic literature?

Published research on this compound focuses on trace elements in health, enzyme structure and function, and protein structure and dynamics. Notable papers include studies on copper binding in the prion protein and histidine phosphorylation in biological systems, with citations ranging from 83 to 420.

How has patent activity for this compound changed in recent years?

Patent filings peaked in 2018 with 21 patents. Activity has remained relatively steady from 2016 to 2022 (14–21 patents annually), with 11 patents filed in the last 3 years and 9 patents in 2024.

Which patent classification areas dominate the intellectual property landscape for this compound?

Peptide and protein chemistry (C07K) accounts for 154 patents, followed by pharmaceutical preparations (A61K) with 146 patents, and therapeutic applications (A61P) with 121 patents. Analytical methods (G01N) and biotechnology processes (C12N) are also significant with 90 and 74 patents respectively.

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